Search clinical trials for: potentially malignant or suspicious lesions

Total 208242 results

National Cancer Institute (NCI)

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Malignant Pleural Mesotheliomas NOS | Esophageal Cancers NOS | Lung Cancer NOS | Thoracic Cancers | Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura

United States
Ain Shams University

Recruiting

Effectiveness of Topical Magnetite Zinc Oxide Composite Nanoparticles in the Management of Oral Potentially Malignant Lesions

Oral Potentially Malignant Lesions

Egypt
Cairo University

Not yet recruiting

Diagnostic Accuracy of Mobile Phone Imaging Compared to Conventional Clinical Examination for Oral Cancer Screening

Oral Cancer | Premalignant Lesion
University of Santiago de Compostela

Recruiting

Role of the Dentist in the Control of the Alcoholic Habit in Patients With Potentially Malignant Oral Lesions (ALCODENT)

Alcohol Drinking | Oral Potentially Malignant Disorders

Spain
Fayoum University
Cairo University

Completed

Cathelicidin LL-37 Relation to Potentially Malignant Lesions

Oral Potentially Malignant Lesions

Egypt
Cairo University
Olfat Shaker

Completed

Evaluation of the Levels of Salivary Paxillin Oral Premalignant and Malignant Lesions

Comparison of Salivary Paxillin Levels in OPMLs and OSCC to Healthy Subjects

Egypt
Fayoum University

Completed

Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant Lesions

Oral Cancer | Oral Premalignant Lesions as Leukoplakia and Lichen Planus

Egypt
Fayoum University

Completed

Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions

Leukoplakia, Oral | Oral Lichen Planus | Potentially Malignant Lesions

Egypt
All India Institute of Medical Sciences, New Delhi

Completed

Photographic Evidence of Oral Precancerous Lesions in Current Tobacco and Areca Nut Users Improves Their Quit Rates

Precancerous Conditions

India
Cairo University

Completed

Clinical and Immunohisochemical Evaluation of Chemopreventive Effect of Thymoquinone on Oral Potentially Malignant Lesions.

Premalignant Lesion

Egypt
Centre Leon Berard

Terminated

A Clinical and Biological Umbrella Protocol for Smoker or Non-smoker Patients With OPML or HNSCC (UMBRELLA)

Head and Neck Squamous Cell Carcinoma (HNSCC) | Premalignant Lesion

France
Cairo University

Unknown

Sensitivity and Specificity of Serum and Salivary CYFRA21-1 in the Detection of Malignant Transformation in Oral Potentially Malignant Mucosal Lesions (Diagnostic Accuracy Study) (CYFRA21-1)

Oral Cancer | Oral Potentially Malignant Lesions

Egypt
University of Zagreb
Croatian Science Foundation

Unknown

Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients (OCSALTM)

Precancerous Lesions | Oral Cavity Squamous Cell Carcinoma | Saliva Altered
Cairo University

Unknown

Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

Oral Cancer

Egypt
Ain Shams University

Unknown

Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions

Oral Cancer

Egypt
University of Palermo

Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography (SYMILIS OCT)

Oral Disease | Oral Cancer | Actinic Keratoses | Oral Leukoplakia | Oral Squamous Cell Carcinoma | Oral Lichen Planus | Graft-versus-host-disease | Proliferative Verrucous Leukoplakia | Actinic Cheilitis | Oral Potentially Malignant Disorder | Oral Erythroplakia | Oral Lichenoid Lesion

Italy
Tseung Kwan O Hospital, Hong Kong

Not yet recruiting

A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy

Benign Thyroid Nodule | Suspicious Malignant Thyroid Nodule
Proteocyte Diagnostics Inc.
The University of Texas Health Science Center, Houston; University of Alabama... and other collaborators

Recruiting

Evaluation of Oral Potentially Malignant Disorders (OPMDs) With STRATICYTE™

Mouth Diseases

United States
National Cancer Institute (NCI)

Recruiting

Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia

Fanconi Anemia | Inherited Bone Marrow Failure Syndrome

United States
Universidad Rey Juan Carlos

Recruiting

Predictive Value of GOCCLES® Device for Early Diagnosis of Oral Potentially Malignant Disorders

Oral Cancer | Oral Potentially Malignant Disorders

Spain
Tanta University

Recruiting

Extended Endoscopic Approaches to Non-malignant Maxillary Sinus Lesions Comparative

Maxillary Sinus Disease | Approach-Approach Conflict

Egypt
Dana-Farber Cancer Institute

Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung Cancer | Cirrhosis | Barrett Esophagus | Hematologic Malignancy | Non-Alcoholic Fatty Liver Disease | Cancer Risk | Vulvar Intraepithelial Neoplasia | Childhood Cancer Survivors | Lung; Node | Non Alcoholic Steatohepatitis | Osteochondroma | Cancer Predisposition Syndrome | Hereditary Cancer Prediction | Adult... and other conditions

United States
Dalarna County Council, Sweden
Uppsala University

Recruiting

Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD) (PMOD)

Mouth Neoplasms

Sweden
Cairo University

Recruiting

Exfoliated Cytology in Detection of Oral Premalignant and Malignant Lesions

Diagnoses Disease | Oral Cancer

Egypt
University of Milan

Recruiting

Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach

Leukoplakia, Oral

Italy
Nicole Baca

Recruiting

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence

Neurofibromatosis Type 1

United States
Proteocyte Diagnostics Inc.

Recruiting

Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment

Oral Neoplasm

Canada
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); University of Miami; University of Florida

Recruiting

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Pancreatic Cancer | Pancreatic Cyst

United States
Toray Industries, Inc

Recruiting

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Solid Tumor | Cholangiocarcinoma | Bladder Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer | Palpable Subcutaneous Malignant Lesions

United States, France
Mayo Clinic

Recruiting

Robotic Surgery in the Seated Position for Benign and Malignant Lesions of the Head and Neck

Head and Neck Cancer | Oropharyngeal Neoplasms

United States
University of Pittsburgh
National Institutes of Health (NIH)

Recruiting

Detection of Genetic Markers of Lung Cancer

Lung Cancer

United States
National Cancer Institute (NCI)

Recruiting

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

HIV | Kaposi's Sarcoma | Primary Effusion Lymphoma | Lymphomas | Multicentric Castleman's Disease

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Ipatasertib as Potentially Targeted Treatment in Cancers With AKT Genetic Changes (MATCH - Subprotocol Z1K)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing LOXO-101 as Potentially Targeted Treatment in Cancers With NTRK Genetic Changes (MATCH - Subprotocol Z1E)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2 Genetic Changes (MATCH - Subprotocol M)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Palbociclib (PD-0332991) as Potentially Targeting Treatment in Cancers With CDK4 or CDK6 Amplification (MATCH - Subprotocol Z1C)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Expression (MATCH - Subprotocol Z1H)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Withdrawn

Testing Nivolumab and BMS-986016 (Relatlimab) as Potentially Targeting Treatment in Cancers That Are LAG-3+ and Have Mismatch Repair Deficiency (MATCH - Subprotocol Z1M)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma
National Cancer Institute (NCI)

Active, not recruiting

Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With mTOR Genetic Changes (MATCH - Subprotocol L)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma | Hematopoietic and Lymphatic System Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Mutations or Fusions (MATCH - Subprotocol K2)

Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Amplifications (MATCH-Subprotocol K1)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders

Dysplasia | Premalignant Lesion | Lip and Oral Cavity Carcinoma | Oral Disorder

United States
Tensive SRL
Advice Pharma Group srl

Active, not recruiting

REGENERA Implant in Localized Non-malignant Breast Lesions Treated by Excision or Lumpectomy - Long-term Follow-up

Breast Diseases

Italy
M.D. Anderson Cancer Center

Withdrawn

Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study

Lung Non-Small Cell Carcinoma | Stage I Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Lung

United States
State University of New York - Upstate Medical...

Completed

Evaluate the Use of the Magnetic Resonance Spectroscopy in Determining if the Breast Tumor is Benign or Malignant

Breast Tumors

United States
Ankara Etlik City Hospital

Completed

Risk-adapted Strategy Including Magnetic Resonance Imaging and Prostate-specific Antigen Density in Blood for Biopsy Decision in Patients With Lesions Suspicious for Prostate Cancer

Prostate Cancer | Prostate Adenocarcinoma

Turkey

Search clinical trials for: potentially malignant or suspicious lesions

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