Search clinical trials for: prostaglandin F2α antagonist

Total 33788 results

ObsEva SA
Iqvia Pty Ltd; Cytel Inc.; Scope International AG; PhinC Development

Active, not recruiting

PoC Study of OBE022 in Threatened Preterm Labour (PROLONG)

Preterm Labor

Spain, Russian Federation, Vietnam, Czechia, Finland, Israel
An-Najah National University

Recruiting

Continuing or Discontinuing ACE/ARBs in Patients With Chronic Kidney Disease Undergoing Coronary Angiography

Chronic Kidney Diseases | Ischemic Heart Disease | Contrast-induced Nephropathy

Palestinian Territory, occupied
Klinički Bolnički Centar Zagreb
University of Zagreb

Recruiting

Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD

Ocular Hypertension | Primary Open-angle Glaucoma

Croatia
Tempest Therapeutics

Active, not recruiting

Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

Colorectal Cancer | Solid Tumor | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Endometrial Cancer | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Solid Tumors With PIK3Ca Mutation

United States
Eda Cetin Ozdemir

Completed

Exploring 8-iso Prostaglandin F2α and Adenosine Deaminase Levels in Periodontal Health and Disease

Periodontal Diseases

Turkey
Cairo University

Completed

Letrozole in Induction of Abortion of Anembryonic Pregnancy

Anembryonic Pregnancy

Egypt
Rottapharm Biotech
Agenus Inc.

Active, not recruiting

A Phase Ib/IIa Study of CR6086 in Combination With Balstilimab in pMMR-MSS Metastatic Colorectal Cancer Patients

Solid Tumor | Metastatic Microsatellite-stable Colorectal Cancer | Mismatch Repair Protein Proficient | Refractory Metastatic Colorectal Cancer

Italy
Brigham and Women's Hospital

Active, not recruiting

Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial

Postpartum Hemorrhage | Uterine Atony

United States
University of Illinois at Chicago

Withdrawn

Evaluation of 20% Betulinic Acid Ointment for Treatment of Dysplastic Nevi (Moderate to Severe Dysplasia)

Dysplastic Nevus Syndrome

United States
Imperial College London
Medical Research Council; Atopix Therapeutics, Ltd.

Completed

Effect of OC459 on the Response to Rhinovirus Challenge in Asthma

Picornaviridae Infections | Asthma | Common Cold | Rhinovirus

United Kingdom
Assiut University

Unknown

Effect Of Topical Prostaglandin F2α Analogs,Fractional CO2 Laser, Excimer Laser Or Their Combination In Treatment Of Vitiligo

Vitiligo | Excimer Laser | Fractional CO2 Laser
St. Antonius Hospital

Completed

Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation (POPular-TAVI)

Myocardial Infarction | Stroke | Bleeding | Aortic Valve Disease

Netherlands, Belgium, Czechia, Luxembourg
NeuroTau, Inc.
The Cleveland Clinic

Unknown

Evaluation of Tolfenamic Acid in Individuals With PSP at 12-Weeks

Progressive Supranuclear Palsy

United States
Samsung Medical Center
Samsung Biomedical Research Institute

Completed

Urinary Nerve Growth Factor (NGF), Prostaglandin E2 (PGE2)and Adenosine Triphosphate (ATP): Potential Biomarkers in Overactive Bladder Patients

Overactive Bladder

Korea, Republic of
Eli Lilly and Company

Completed

A Study of LY3031207 in Healthy Subjects

Healthy Volunteers

United States
Eli Lilly and Company

Terminated

A Multiple-dose Study of LY3031207 in Healthy Participants

Healthy Volunteers

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase Ⅱa Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy Adult With Influenza Fever

Influenza
Merck Sharp & Dohme LLC

Completed

Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

Ocular Hypertension | Glaucoma
Stanford University

Withdrawn

The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.

Ocular Hypertension | Glaucoma | Thyroid Eye Disease

United States
University of Essex

Completed

Ischemia Reperfusion: Prostaglandins and Antioxidants

Ischemic Reperfusion Injury

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153)

Ocular Hypertension | Glaucoma
Alcon Research

Completed

Efficacy and Safety of Adding Azarga to Prostaglandin Monotherapy

Glaucoma

Germany
Monica Levy Andersen

Completed

Mother-caregivers of Children With Duchenne Muscular Dystrophy (DMDK)

Other Diseases or Conditions

Brazil
Postgraduate Institute of Medical Education and...

Completed

Comparison of Topical Latanoprost vs Topical Corticosteroid in Treatment of Localized Alopecia Areata (COLA)

Alopecia Areata

India
Orlando Health, Inc.

Withdrawn

Tolfenamic Acid, Gemcitabine and Radiation for Locally Advanced or Metastatic Pancreatic Cancer Requiring Radiation

Pancreatic Cancer

United States
Ophthalmic Consultants Centres, Canada
Alcon Research

Completed

A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma (DVX)

Ocular Hypertension | Open-Angle Glaucoma

Canada
University of Campinas, Brazil

Unknown

The Influence of Glycaemia and Insulinemia on Vasomotor Endothelial Function After Myocardial Infarction (INGLIVEF)

Myocardial Infarction

Brazil
Alcon Research

Completed

Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy

Ocular Hypertension | Glaucoma
Indiana University

Completed

Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data

Glaucoma

United States
University of Campinas, Brazil

Completed

Blood-aqueous Barrier Changes After the Use of Timolol and Prostaglandin Analogues Fixed Combination in Pseudophakic Patients With POAG

Uveitis, Anterior | Cystoid Macular Edema

Brazil
Alcon Research

Withdrawn

Assessing the Efficacy of DuoTrav as a Replacement Therapy in Glaucoma Patients in Russia

Ocular Hypertension | Glaucoma
Samuel Lunenfeld Research Institute, Mount Sinai...
University of Toronto; Canadian Anesthesiologists' Society

Completed

In Vitro Myometrial Contractions in Laboring and Non-laboring Women

Postpartum Hemorrhage

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer

Prostate Cancer

United States
Biosense Webster, Inc.

Completed

A Comparison of Antiarrhythmic Drug Therapy and Radio Frequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation

Paroxysmal Atrial Fibrillation

United States, France, Switzerland
Danish Headache Center

Completed

Prostaglandin F2alpha in a Human Headache Model

Headache

Denmark
Danish Headache Center

Completed

EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache Model

Headache, Migraine

Denmark
University of Southern California

Terminated

The Effect of Mifepristone on the Expression of Cervical Prostaglandin EP3 Receptors (EP3)

Pregnancy | Cervical Prostaglandin EP3 Receptors

United States
Singapore Eye Research Institute

Unknown

Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma

Glaucoma

Singapore
University of Magdeburg
Sanofi

Unknown

Irbesartan and Adhesion Molecules in AF (CREATIVE-AF)

Persistent Atrial Fibrillation

Germany
Allergan

Completed

Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Canada
Bp Consulting, Inc
Allergan

Completed

Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Canada
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Dose Optimization of Caffeine for HIE

Hypoxic-Ischemic Encephalopathy

United States
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.

Breast Cancer Subjects

China
Fudan University

Recruiting

Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancer

Advanced Breast Cancer | HR+/HER2- Breast Cancer

China
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal
University of Milan
Kolfarma s.r.l. - Italy; Fondazione Telethon

Recruiting

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD) (NUTRIENT)

CDKL5

Italy
Shanghai Zhongshan Hospital

Recruiting

Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery

Growth Hormone Treatment

China
AstraZeneca

Not yet recruiting

Volrustomig Priming Regimens Exploratory Phase II Platform Study (eVOLVE-01)

Non-small Cell Lung Cancer
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China
Mongi Slim Hospital

Recruiting

Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia (OPDPH)

Post-Dural Puncture Headache

Tunisia

Search clinical trials for: prostaglandin F2α antagonist

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