Search clinical trials for: randomized, double blinded and controlled trial

Total 475998 results

University of Aarhus
Aarhus University Hospital; University of Copenhagen; Gødstrup Hospital; Statens... and other collaborators

Not yet recruiting

The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial (BEGIN)

Healthy | Healthy Nutrition
Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
Sichuan Cancer Hospital and Research Institute
Sichuan Province, Department of Science and Technology

Not yet recruiting

3D-printed Reconstruction Automated Matching System Predicts Size of Double-lumen Tube: a Prospective Double-blinded Randomized Controlled Trial

Lung Diseases | Lung Cancer | Tracheal Intubation Morbidity | Throat Injury | Bronchus; Injury
Eva Pharma
MARC-CRO

Recruiting

Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)

Polyneuropathy, Diabetic

Egypt
Assiut University

Not yet recruiting

Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine

Inguinal Hernia
Novartis Pharmaceuticals

Recruiting

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Chronic Spontaneous Urticaria

United States, Singapore, Spain, Germany, Turkey, Italy, Hong Kong, China, Argentina, Malaysia, Thailand, Poland, Japan, Netherlands, South Africa, Chile, Canada
Xeolas Pharmaceuticals Limited

Recruiting

A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction (XEOLAS)

Bone Loss, Alveolar

Spain
Fondation Lenval

Recruiting

EMDR Therapy in Young Children, a Double-blinded Randomized Controlled Trial (EMDRJEER)

Anxiety Disorders | Stress, Psychological | Trauma, Psychological

France
Oslo Metropolitan University
University of Oslo; Det Glutenfrie Verksted

Recruiting

Glutenfree, Gut Microbiota and Metabolic Regulation (GRAIN)

Celiac Disease

Norway
Istituto Ortopedico Rizzoli

Recruiting

Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis

Knee Osteoarthritis

Italy
William Beaumont Army Medical Center

Recruiting

A Prospective Randomized Double Blinded Controlled Trial of Non-Operative Management of TFCC Injuries (TFCC)

Wrist Injuries | PRP

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

Zika Virus Infection

United States
Odense University Hospital

Active, not recruiting

The DANish COronary DEcalcification (DANCODE) Trial (DANCODE)

Coronary Artery Disease

Denmark
Rigshospitalet, Denmark

Terminated

A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial

Hypogonadotropic Hypogonadism | Hypogonadism | Hypogonadism, Male

Denmark
Woolcock Institute of Medical Research
University of Sydney

Completed

Cannabinol Use in Patients With Insomnia Disorder (CUPID)

Insomnia Disorder

Australia
International AIDS Vaccine Initiative
Massachusetts General Hospital; GlaxoSmithKline; Fred Hutchinson Cancer Research... and other collaborators

Completed

A Randomized, Double-blinded, Placebo-controlled, Dose-escalation Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV Envelope Protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in Healthy, HIV-1 Uninfected Adults

HIV Infections

United States, Kenya
Yu Qin

Active, not recruiting

An Investigator Initiated, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Safety, Immunogenicity and Efficacy of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) in Adults Aged 18 Years and Older

Prevention of COVID-19 Caused by SARS-CoV-2

China
NovaCell Technology Inc.

Completed

A Single-center, Randomized, Double-blinded, Placebo-controlled, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of NCP112

Atopic Dermatitis

Korea, Republic of
Globe Biotech Limited

Completed

A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002

Natural Blood and Blood Product Toxicity

Bangladesh
prof. dr. Jan Deprest

Completed

Use of Fractional CO2 Laser for the Treatment of Vulvovaginal Atrophy: a Double-blinded Randomized Placebo-controlled Clinical Trial. (CO2VVA)

Vulvovaginal Atrophy

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized, Placebo-Controlled, Double-Blinded Phase I Safety and Immunogenicity Trial of Recombinant Envelope Protein, HIV-1 SF-2 rgp120 (BIOCINE), Combined With MF59 in HIV-1 Uninfected Adult Volunteers

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase I Trial to Evaluate the Safety and Immunogenicity of Live Recombinant Canarypox ALVAC-HIV vCP205 Combined With GM-CSF in Healthy, HIV-1 Uninfected Volunteers

HIV Infections

United States
University of Oslo
Oslo University Hospital

Enrolling by invitation

Health Effects of Cetoleic Acid (A Randomized Double Blinded Controlled Trial)

Healthy Diet

Norway
Gachon University Gil Oriental Medical Hospital
Kyung Hee University Hospital at Gangdong; Kyunghee University Medical Center; Sangji University Oriental Medical Hospital and other collaborators

Completed

Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial

Cold Hypersensitivity

Korea, Republic of
Gachon University Gil Oriental Medical Hospital
DongGuk University; Sangji University Oriental Medical Hospital, Korea

Completed

A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -

Obesity | Metabolic Syndrome

Korea, Republic of
Novo Nordisk A/S

Completed

A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs (DUAL™ II Japan)

Diabetes Mellitus, Type 2 | Diabetes

Japan
University of Texas Southwestern Medical Center
Department of Urology

Completed

Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome

Constipation
BioGaia AB

Completed

Double-blinded, Randomized, Placebo-controlled Study Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection

Recurrent Urinary Tract Infection in Adult Women

Sweden
Chinese University of Hong Kong
National University Hospital, Singapore; Singapore General Hospital; Changi General... and other collaborators

Completed

Partially Covered Versus Uncovered Pyloro-duodenal Stents for Unresectable Malignant Gastric Outlet Obstruction. A Double Blinded Randomised Controlled Trial.

Unresectable Malignant Gastric Outlet Obstruction

China
Tel-Aviv Sourasky Medical Center

Unknown

The Effect of Low-Dose vs High-Dose Epidural Fentanyl on Gastric Emptying - A Prospective Double-Blinded Randomized Controlled Trial

Aspiration | Effects of; Anesthesia, Spinal and Epidural, in Pregnancy

Israel
Evofem Inc.
Clinical Research Management, Inc.

Completed

Phase 2B/3 Double-blinded Placebo-controlled

Chlamydia Trachomatis Infection

United States
Louisiana State University Health Sciences Center...
LSUHSC-NO

Unknown

A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis (NO-HERNIA)

Incisional Hernia

United States
Hong Kong Baptist University
Queen Elizabeth Hospital, Hong Kong; Prince of Wales Hospital, Shatin, Hong...

Completed

A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation

Functional Constipation | Gastrointestinal Disorders

China
Tasly Biopharmaceuticals Co., Ltd.

Completed

Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial (PROUD)

Acute Ischaemic Stroke

China
Shanghai University of Traditional Chinese Medicine

Unknown

The Efficacy and Safety of Zhigancao Tang Granule for HFpEF of Qi-Yin Dificiency (HFpEF)

Heart Failure With Preserved Ejection Fraction

China
Rush University Medical Center
People's Liberation Army General Hospital

Completed

The Role of Gas Flow in Transnasal Pulmonary Aerosol Delivery: A Double-blinded, Randomized Controlled Trial

COPD Asthma

China
National Institute of Diabetes and Digestive and...

Completed

A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy

Biliary Atresia

United States
Oslo University Hospital
Sykehuset Ostfold; Betanien Hospital

Terminated

Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial

Stress Fracture Foot | Stress Fracture Ankle

Norway
Mayo Clinic

Completed

Changes in Intestinal Permeability 4 Hours After Gluten Challenge

Duodenal Diseases | Celiac Disease | Gluten Sensitivity | Gluten Enteropathy | Immune System and Related Disorders | Wheat Hypersensitivity

United States
Guang'anmen Hospital of China Academy of Chinese...

Completed

Topical Tripterygium Wilfordii Gel for Moderate Activity Rheumatoid Arthritis

Arthritis, Rheumatoid

China
Kristina Tedroff
Karolinska University Hospital; Danderyd Hospital

Terminated

Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial (BATCP)

Pain | Cerebral Palsy, Spastic

Sweden
University of North Carolina, Chapel Hill

Terminated

Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears

Rotator Cuff Tear

United States
Merck Sharp & Dohme LLC

Completed

A Placebo-Controlled, Double-Blinded, Randomized Trial of Remicade in Korean Patients With Rheumatoid Arthritis Despite Methotrexate (Study P04280)(COMPLETED)

Arthritis, Rheumatoid
University Hospital of North Norway

Completed

Fecal Microbial Transplantation in Treatment of Irritable Bowel Syndrome; a Double Blinded Placebo Controlled Trial. (REFIT)

Irritable Bowel Syndrome

Norway
University of Aarhus
Albert Einstein College of Medicine; Pfizer; GCP-unit at Aarhus University Hospital... and other collaborators

Completed

Pregablin for Anxiety-comorbidity in Patients With Schizophrenia (PACS)

Schizophrenia | Anxiety-comorbidity to Schizophrenia

Denmark
General Hospital of Ningxia Medical University

Completed

The Effects of Different Doses of Dexmedetomidine on Propofol Requirement for Loss of Consciousness Undergoing Bispectral Index: a Double-blinded, Placebo-controlled Trial

Loss of Consciousness
Bundang CHA Hospital

Unknown

Clinical Trial to Evaluate the Potential Efficacy and Safety of Human Umbilical Cord Blood and Plasma

Aging

Korea, Republic of
Portuguese Oncology Institute, Coimbra

Completed

Simethicone and N-acetylcysteine in Upper Endoscopy - Prospective Double-blinded Randomized Controlled Trial

Gastric Mucosal Lesion

Portugal
Medical University of Vienna

Completed

A Prospective Randomized Double-Blinded Placebo Controlled, Explorative Phase I Trial to Investigate the Safety and Tolerability of Two Different Doses of Topically Administered APOSEC™ in Healthy Male Subjects With Artificial Dermal Wounds

Healthy | Artificial Dermal Wound

Austria
Asian Institute of Gastroenterology, India

Completed

Efficacy of Enteral Glutamine Supplementation in Patients With Predicted Severe Acute Pancreatitis- A Double-Blinded Randomized Controlled Trial

Acute Pancreatitis

India

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