Search clinical trials for: safety, tolerability and pharmacokinetics.

Total 473061 results

Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study With Repeated Doses of Stalevo

Pharmacokinetics

Finland
Pfizer

Completed

Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer

Neurogenic Detrusor Overactivity

Belgium
IRCCS Policlinico S. Matteo

Unknown

Improving Immunosuppressive Therapy in Heart Transplantation

Immunosuppression | Rejection Heart Transplant

Italy
University Hospital, Clermont-Ferrand

Unknown

Intra-monocyte Imiglucerase Kinetics in Gaucher Disease (CIMI)

Gaucher Disease

France
Wockhardt

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Oral WCK 2349

Pharmacokinetics
Philip Morris Products S.A.

Completed

Product Use and Adaptation, Safety and Tolerability of P3P in Adult Healthy Smokers Switching to it

Pharmacokinetics

Russian Federation
Mycenax Biotech Inc.

Completed

Phase I, Pharmacokinetic, Safety and Tolerability Study in Healthy Volunteers

Pharmacokinetics

Australia
University of Sao Paulo

Completed

Pharmacokinetic Profile of the Calcium-salt and Free Acid Forms of β-hydroxy-β-methylbutyrate in Humans

Healthy

Brazil
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

To Assess Pharmacokinetics, Safety and Tolerability of TEV-48125 in Japanese and Caucasian Healthy Subjects After a Single Subcutaneous (SC) Administration of TEV-48125

Pharmacokinetics

United States
Eagle Pharmaceuticals, Inc.

Completed

Study to Evaluate the Safety, Tolerability, and PK of Fulvestrant After IM Administration

Pharmacokinetics

United States
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics and Pharmacodynamics, Safety and Tolerability of P3P

Pharmacokinetics

Switzerland
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of AZD8566.

Pharmacokinetics

United Kingdom
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Methotrexate | Pharmacokinetics of 7-hydroxymethotrexate

United States
Astellas Pharma Inc

Completed

A Study to Assess the Effect of ASP1941 and Mitiglinide on Their Plasma Concentration

Healthy | Pharmacokinetics of ASP1941 | Pharmacokinetics of Mitiglinide

Japan
Merckle GmbH

Completed

PK, PD, Safety and Tolerability of Lipegfilgrastim in Healthy Japanese and Caucasian Participants

Pharmacokinetics | Pharmacodynamics

United Kingdom
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001)

Cancer | Pharmacokinetics

Belgium
Repros Therapeutics Inc.

Completed

A Dose Escalating Study to Determine the Tolerability and PK of a Single Dose of Androxal

Pharmacokinetics | Tolerability

United States
Usona Institute

Completed

Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers

Pharmacokinetics | Tolerability | Safety

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Methadone

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Methadone

United States
Astellas Pharma Inc
Basilea Pharmaceutica

Completed

Drug Interaction Study of Isavuconazole and Midazolam

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Midazolam

United States
RH Nanopharmaceuticals
Center for Bioequivalence Studies and Clinical Research

Completed

Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers

Pharmacokinetics | Tolerability | Safety

Pakistan
Daiichi Sankyo, Inc.

Completed

Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants.

Pharmacokinetics | Tolerability | Safety

United Kingdom
Rock Creek Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Modified and Immediate Release Anatabine Citrate Formulations

Pharmacokinetics of Anatabine

United Kingdom
Astellas Pharma Inc

Completed

To Evaluate the Blood and Urine Concentration and the Safety and Tolerability of Increasing Repeated Doses of Mirabegron (YM178) OCAS in Healthy Young and Elderly Males and Healthy Young and Elderly Females

Healthy Subjects | Pharmacokinetics

Netherlands
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Digoxin

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Digoxin

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and a Single Dose of Bupropion

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Bupropion

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Sirolimus

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Assess the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Mycophenolate Mofetil in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Plasma Mycophenolic Acid (MPA) | Pharmacokinetics of Plasma Phenolic Glucuronide of MPA (MPAG)

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of the Effect of Ketoconazole at Steady State on the Pharmacokinetics of a Single Dose of Isavuconazole in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Ketoconazole

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Dextromethorphan

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug-drug Interaction Study Between Lopinavir/Ritonavir and Isavuconazole

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Lopinavir/Ritonavir

United States
Janssen-Cilag International NV

Completed

A Single Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-42165279 in Healthy Male Participants

Healthy Volunteers | Pharmacokinetics

Belgium
Sun Yat-sen University

Completed

Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor

Pharmacokinetics | Tolerability | Endostatin

China
Pfizer

Completed

Open-Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Tamoxifen When Coadministered To Healthy Post-Menopausal Female Subjects

Pharmacokinetics

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Atorvastatin

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Atorvastatin

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine

Healthy Subjects | Pharmacokinetics of Caffeine | Pharmacokinetics of Repaglinide

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Metformin

United States
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

A Study to Assess the Safety and Pharmacokinetics of Isavuconazole in Healthy Chinese Volunteers

Healthy Volunteers | Pharmacokinetics of BAL4815 | Pharmacokinetics of BAL8728

China
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Prednisone in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Prednisolone

United States
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Tacrolimus

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Tacrolimus

United States
AstraZeneca

Completed

A Study to Assess the Pharmacokinetics and Safety of Single Doses of Anifrolumab in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Safety

United States
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
AstraZeneca

Withdrawn

Phase I, Single Centre, Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043 (AZD3043)

Pharmacokinetics | Sedation | Tolerability | Safety
Astellas Pharma Inc

Completed

A Study to Evaluate Safety of Multiple Dose of ASP0456 in Healthy Subjects

Healthy | Pharmacokinetics of ASP0456

Japan
Astellas Pharma Inc

Completed

A Safety and Pharmacokinetics Study of ASP0456 in Healthy Subjects

Healthy | Pharmacokinetics of ASP0456

Japan
Bambino Gesù Hospital and Research Institute

Completed

Vancomycin and Cefoxitin During Pediatric Cardiopulmonary Bypass (VANCOCEF)

Congenital Heart Disease

Italy
Grünenthal GmbH

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GRT9906 Prolonged Release Tablets After Dose Escalation in Healthy Subjects

Pharmacokinetics

Germany
AstraZeneca

Completed

Single + Multiple Ascending Dose and Food Effect Study of AZD7986 in Healthy Volunteers, PK, PD and Safety Study

Safety, Pharmacokinetics, Pharmacodynamics, Food Effect

United Kingdom
Astellas Pharma Europe B.V.

Withdrawn

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP3700 in Healthy Subjects

Healthy Volunteers | Pharmacokinetics of ASP3700

Search clinical trials for: safety, tolerability and pharmacokinetics.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Africa

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations