Search clinical trials for: severe infections

Total 62982 results

Washington University School of Medicine

Not yet recruiting

Propranolol for the Treatment of Kaposi Sarcoma in Adults

Kaposi Sarcoma

United States
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
Hadassah Medical Organization
London North West Healthcare NHS Trust

Not yet recruiting

Severe COVID-19 Infection in Children Presenting to EDs in Israel and England (SPICE)

COVID-19 | Inflammatory Response
University Hospital, Brest

Not yet recruiting

Evolution of the Lymphocyte Phenotype in Patients With Infection in Intensive Care Unit (REAPHEN)

Patients Undergoing Esophagectomy | Patients With Severe Polytrauma | Patients With Severe Neurological Lesion | Patients With Abdominal Infection
MoonLake Immunotherapeutics AG

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
MoonLake Immunotherapeutics AG

Recruiting

Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Novavax

Not yet recruiting

Phase 3 Strain Change Study for SARS-CoV-2 rS Vaccines (COVID-19)

Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Pfizer

Not yet recruiting

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Healthy Participants | Biological Availability
Sanofi
Regeneron Pharmaceuticals

Recruiting

Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France (OPALE)

Chronic Rhinosinusitis With Nasal Polyposis

France, Réunion
Uppsala University Hospital

Not yet recruiting

Mechanisms of Acute Kidney Injury in Severe Infections (PET-AKI)

Sepsis | AKI - Acute Kidney Injury | Positron Emission Tomography (PET)
Qin Ning

Recruiting

A Case-control Study on the Clinical Characteristics of 28-day and 90-day Death From Severe Anthrax

Anthrax

China
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function

Alcoholic Hepatitis

India
Central Hospital, Nancy, France

Not yet recruiting

Multiplex PCR for Severe Respiratory Infections During the COVID-19 Pandemic (VirCoV+)

Viral Pneumonia

France
Shaheed Zulfiqar Ali Bhutto Medical University

Recruiting

Role of Probiotics as Adjunct Therapy Along With Standard Care in Decreasing Hospital Stay and Improving Symptoms in Pediatric Patients Admitted With Severe Pneumonia

Pneumonia | Probiotics

Pakistan
Florida Academic Centers Research and Education...

Not yet recruiting

Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa

Hidradenitis Suppurativa
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Severe Group A Streptococcus Infections in Paris, France, 2018-2023 (IGASI)

Invasive Group A Beta-Haemolytic Streptococcal Disease

France
Capital Medical University

Recruiting

Diagnosis and Treatment Strategy Optimization of Severe Pneumonia Based on Multi-omics Data Integration

Severe Community-acquired Pneumonia

China
EMS

Not yet recruiting

Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. (SIERRA)

Allergic Rhinitis
Zhejiang University
Beijing YouAn Hospital; Beijing Ditan Hospital; Huashan Hospital; Qilu Hospital...

Not yet recruiting

A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With Infection

Liver Failure
Nantes University Hospital

Not yet recruiting

Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype (HAP-DEX)

Hospital Acquired Pneumonia

France
Association Clinique Thérapeutique Infantile du...
Centre National de Référence des staphylocoques; GFRUP (Groupe Francophone... and other collaborators

Recruiting

CommunautAry Pediatric bacteRial Infection in Intensive CarE Unit (CAPRICE)

Severe Infection | Hospitalized Children | Invasive Bacterial Infection

France
Siriraj Hospital

Not yet recruiting

Early Intravenous Hydrocortisone in Sepsis

Shock, Septic | Sepsis Severe

Thailand
Incyte Corporation

Recruiting

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa (STOP-HS LTE)

Hidradenitis Suppurativa (HS)

United States, Austria, Belgium, Canada, Germany, Poland, Spain, Australia, Denmark, France, United Kingdom, Japan, Bulgaria, Netherlands, Czechia, Greece, Italy
Oluwasegun Aremu
Orthopaedic Trauma Association

Not yet recruiting

External Fixator or Antibiotic-coated Plate in Severe Open Long Bone Fractures

Fracture Related Infection

Nigeria
Hospices Civils de Lyon

Recruiting

PHAGEinLYON Clinic Cohort Study: a Descriptive Study of Severe Infections Treated With Phage Therapy at the HCL.

Severe Infection

France
Amsterdam University Medical Centers (UMC), Location...
Amsterdam UMC, location VUmc; Flevoziekenhuis

Recruiting

Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room (BIOSEP)

Infections | Sepsis | Septic Shock | Infection, Bacterial | Sepsis, Severe | Infection Viral | Infections, Respiratory

Netherlands
Central South University

Recruiting

Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model

Severe Infection

China
Centre Hospitalier Universitaire, Amiens
CH Montdidier

Recruiting

Intestinal Microbiota Profiling in Severe Acute Alcoholic Hepatitis Patients (HepatAlc-IM)

Corticosteroids | Intestinal Microbiota | Alcohol | Severe Acute Alcoholic Hepatitis

France
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Role of Extended Low Dose Prednisolone in Achieving Clinical and Biochemical Remission in Steroid Responsive Severe Alcoholic Hepatitis

Severe Alcoholic Hepatitis

India
Artcline GmbH
ZKS Jena

Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up (ReActIF- LTO)

Severe Sepsis

Germany
Guangzhou 8th People's Hospital

Recruiting

Risk Identification Factors for Pulmonary Function Impairment in AIDS Patients Recovered From Severe Pneumonia

Pneumonia | AIDS

China
Sanofi

Recruiting

Proof-of-concept Study Evaluating Subcutaneous Amlitelimab in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis

Chile, Canada, Spain, United States, Australia, Portugal, Hungary, Italy, Germany
First Affiliated Hospital of Zhejiang University

Recruiting

Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter, Cohort Study (MASS)

Severe Pneumonia

China
Institut National de la Santé Et de la Recherche...

Not yet recruiting

Genetic Susceptibility to Severe Infections (PREDISPOSITI)

Infectious Disease
Harvard School of Public Health (HSPH)
Muhimbili University of Health and Allied Sciences

Not yet recruiting

Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania

Neonatal Infection

Tanzania
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Sunnybrook Health Sciences Centre

Not yet recruiting

Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments (PCS-HBOT)

COVID-19 | Fatigue | Fatigue Syndrome, Chronic | Post-COVID-19 Syndrome | Post COVID-19 Condition | Post-COVID Syndrome

Canada
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
Pfizer
Kaiser Permanente

Recruiting

A Study to Learn About ABRYSVO Vaccine in Older Adults to Prevent Severe Respiratory Syncytial Virus (RSV) Infection.

Respiratory Syncytial Viruses

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Role of Vitamin D in Prevention of Dengue Haemorrhagic Fever and Dengue Shock Syndrome

Dengue Fever

Bangladesh
National and Kapodistrian University of Athens

Recruiting

Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma (MepoRiNaPAs)

Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps | Severe Eosinophilic Asthma

Greece
Institute of Tropical Medicine, Belgium
KU Leuven; Leiden University Medical Center; Barcelona Institute for Global Health and other collaborators

Recruiting

Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX (IMMETASEX)

Uncomplicated Malaria | Severe Malaria | Asyptomatic Plasmodium Infection

Mozambique, Belgium, Burkina Faso
Eli Lilly and Company

Recruiting

A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Australia, Canada, Germany, Greece, Poland
Centers for Disease Control and Prevention

Recruiting

Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV (VIRISMAP)

HIV Infections | Monkeypox | AIDS

United States
Longbio Pharma

Recruiting

Efficacy and Safety of LP-003 in Moderate-to-severe Seasonal Allergic Rhinitis Adult

Seasonal Allergic Rhinitis

China
Lemonex

Recruiting

Evaluation of Safety and Immunogenicity of a SARS-CoV-2(Severe Acute Respiratory Syndrome Coronavirus 2) Booster Vaccine (LEM-mR203)

COVID-19 Infection | COVID-19 Vaccine Adverse Reaction

Korea, Republic of
Sanofi
Kymera Therapeutics, Inc.

Recruiting

A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa (ZEN)

Hidradenitis Suppurativa

Spain, United States, Germany, Greece, Poland
Postgraduate Institute of Dental Sciences Rohtak

Not yet recruiting

Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker

Gingivitis | Inflammatory Response | Periodontitis Chronic Generalized Severe

India
Institut National de la Santé Et de la Recherche...

Recruiting

Characterization of Natural Killer Cells in Severe Asthma Patients in Comparison With Control Subjects (NKAS)

Asthma Acute

France
Tongji Hospital

Recruiting

A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome

Severe Fever With Thrombocytopenia Syndrome

China

Search clinical trials for: severe infections

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