Search clinical trials for: severe renal failure

Total 35190 results

Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma (METAKIT)

Multi-organ Failure After Severe Trauma

France
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Centre Hospitalier Universitaire de Nīmes
CHU Arnaud de Villeneuve MONTPELLIER

Recruiting

Tolerability and Safety of CARDIOMEMS™ Intracardiac Continuous Cardiac Hemodynamic Monitoring Device in Patients With Cardio Renal Syndrome With Severe Renal Impairment (CARDIOMEMS)

Heart Failure | Renal Insufficiency

France
Guillermo Galeote; MD, PhD

Recruiting

Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure (CRATER)

Coronary Artery Disease | Chronic Renal Failure

Spain
Odense University Hospital
Novo Nordisk A/S; Department of Nephrology, Odense University Hospital; The A... and other collaborators

Recruiting

Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH)

Kidney Failure, Chronic | Kidney Injury | Risk Reduction | Contrast-induced Nephropathy

Denmark
University Hospital, Strasbourg, France

Recruiting

Patients With Acute Renal Failure During Severe COVID-19 (IR-EST-POSTCOV)

Renal Failure Chronic

France
Children's Hospital Medical Center, Cincinnati
Memorial Sloan Kettering Cancer Center; Fred Hutchinson Cancer Center

Recruiting

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

Fanconi Anemia | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Severe Marrow Failure

United States
University Medical Center Groningen
AstraZeneca; Dutch Kidney Foundation

Enrolling by invitation

The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD

Heart Failure | Death | Kidney Disease, Chronic | Kidney Failure | Renal Transplant Failure

Netherlands, Germany, Australia
Pfizer

Terminated

A Study to Measure the Amount of Study Medicine in Blood in Adult Participants With COVID-19 and Severe Kidney Disease

COVID-19

United States
Cara Therapeutics, Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Hungary, Australia, Germany, Korea, Republic of, Poland, Argentina, Brazil, Bulgaria, Italy, Mexico, Romania, Spain
Peking University People's Hospital

Terminated

SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal Insufficiency

Renal Insufficiency, Chronic | Heart Failure With Reduced Ejection Fraction

China
Vanderbilt University Medical Center

Active, not recruiting

Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure

Renal Failure | Severe Obesity

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Takeda

Completed

A Phase 3, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 3, Multicenter, Open-label, Long-term Study of SYR-472 (25 mg) in Patients With Type 2 Diabetes Mellitus Complicated by Severe Renal Impairment or End-stage Renal Disease

Type 2 Diabetes Mellitus

Japan
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
University of Vermont
Medical University of South Carolina; University of Washington; University of...

Active, not recruiting

Communication During Hospitalization About Resuscitation Trial (CHART)

End Stage Renal Disease | Severe Life-limiting COPD | Severe Life-limiting Heart Failure | Severe Life-limiting Cirrhosis | Severe Life-limiting Malignancy | Severe Functional Impairment

United States
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire

Completed

High Dose Therapy Followed by Autologous Transplantation for Myeloma Patients With Severe Renal Impairment (IRMYG)

Multiple Myeloma | Renal Failure

France, Belgium, Algeria, Lebanon
Takeda

Completed

Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Severe Renal Impairment or End-stage Renal Disease"

Type 2 Diabetes Mellitus

Japan
Rush University Medical Center
John H. Stroger Hospital

Completed

Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging (ASSUAGE-CKD)

Patients With Severe Chronic Kidney Disease Being Evaluated With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson

United States
Centre hospitalier de l'Université de Montréal...
Sunnybrook Health Sciences Centre; University of Alberta; Unity Health Toronto; University of Kentucky and other collaborators

Completed

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury (ECHO-AKI)

Acute Kidney Injury | Ultrasonography | Fluid Overload

Canada, United States
Amgen

Completed

Estimation Study to Assess the Effect of Severe Renal Impairment and End-stage Renal Disease Hemodialysis on the Pharmacokinetics of Evolocumab

Hyperlipidemia | Mixed Dyslipidemia

United States
Patient Care America
Baxter Healthcare Corporation

Active, not recruiting

Impact of IDPN on Nutrition Markers in Patients Receiving ICHD

End-stage Renal Disease | Malnutrition; Protein

United States
Albert Einstein College of Medicine

Withdrawn

Safety and Efficacy of Apixaban in Severe Renal Impairment

Anticoagulant-induced Bleeding | Renal Disease, End Stage

United States
Columbia University
Constant Therapeutics LLC

Completed

TXA127 for the Treatment of Severe COVID-19

COVID-19

United States
Amgen

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Heart Failure

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Agence Sanitaire et Sociale de Nouvelle Calédonie
Institut Pasteur; World Health Organization; Pacific Community; Institut de la...

Suspended

Baromètre Santé Adulte 2021-2022

Diabetes | Renal Failure | Chronic Disease | Hypercholesterolemia | Malaria | SARS-CoV Infection | Dengue Fever | Chikungunya | Zika | Ross River

New Caledonia
Acacia Pharma Ltd

Completed

PK Study of IV and Oral Amisulpride in Subjects With Severe Renal Impairment

Renal Disease, End Stage

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Completed

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Puerto Rico
Imperial College London
National Institute for Health Research, United Kingdom; Imperial College Healthcare...

Withdrawn

MRI Assessment of Myocardial Fibrosis Associated With Monocyte Phenotype in End Stage Renal Failure (CM3)

Myocardial Fibrosis | Heart Failure | End Stage Renal Failure on Dialysis | Chronic Kidney Disease Stage V | Chronic Kidney Disease, Stage IV (Severe)

United Kingdom
SeaStar Medical

Terminated

Efficacy Study of a Selective Cytopheretic Device (SCD) in Patients With Acute Kidney Injury

Acute Kidney Injury

United States
Turku University Hospital
Satakunta Central Hospital

Terminated

Supportive Treatment of Severe Heart Failure by Renal Denervation (Heart-RND)

Heart Failure

Finland
Novartis Pharmaceuticals

Completed

PK of Serelaxin in Severe Renal Impairment and ESRD (CRLX030A2102)

End-Stage Renal Disease | Renal Failure, Chronic

Germany
Centre Hospitalier Universitaire, Amiens

Withdrawn

Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study (METsuiviIRC)

Renal Insufficiency, Chronic

France
Centre Hospitalier le Mans
Le Mans Universite

Withdrawn

Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis. (PIONNIER)

Fatigue | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease stage3 | Chronic Kidney Failure | Chronic Kidney Disease, Stage 4 (Severe)
University of Nottingham
British Heart Foundation

Terminated

PD-HF: A Trial of Peritoneal Dialysis in Patients With Severe Heart Failure and Chronic Kidney Disease (PD-HF)

Heart Failure | Chronic Kidney Disease

United Kingdom
Aristotle University Of Thessaloniki

Unknown

Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices

End Stage Renal Disease | Hypotension During Dialysis | Protein Malnutrition | Arterial Sclerosis

Greece
Ruijin Hospital

Unknown

Study Of Bacterial/Fungal Infections in Hospitalized Patients With Liver Cirrhosis in China (SONIC)

Cirrhosis

China
Centre Hospitalier Universitaire de Nīmes
Technology Transfer Accelerator Offices _ SATT AxLR

Completed

Concordance Between the Foot-to-Apex Systolic Interval and the Auscultatory Method for Measurement of Brachial Systolic Pressure in Patients With Severe Renal Failure (SFATI-IRC)

Renal Insufficiency

France
Cumberland Pharmaceuticals

Completed

A Study to Evaluate the Effect of Renal Function on the Biological Activity of Telavancin

Kidney Diseases | End Stage Renal Disease

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia (Mafia)

Fanconi Anemia | Severe Aplastic Anemia

United States
Alice Ho Miu Ling Nethersole Hospital

Completed

IV Antibiotics With Lavage for Severe PD Peritonitis

Peritonitis | Kidney Failure

Hong Kong
Anemia Working Group Romania

Withdrawn

Intravenous Iron in Patients With Severe Chronic Heart Failure and Chronic Kidney Disease

Anemia | Chronic Kidney Disease | Chronic Heart Failure

Romania
AbbVie

Completed

Ombitasvir/ABT-450/Ritonavir and Dasabuvir With or Without Ribavirin in HCV Genotype 1-Infected Adults With Chronic Kidney Disease

Chronic Hepatitis C | Hepatitis C Virus | Severe Renal Impairment | Compensated Cirrhosis | End-stage Renal Disease
Emory University
Children's Healthcare of Atlanta

Terminated

Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation

Sickle Cell Disease | Fanconi Anemia | Thalassemia | Severe Congenital Neutropenia | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Leukocyte Adhesion Deficiency | Dyskeratosis-congenita | Chediak-Higashi Syndrome | Chronic-granulomatous Disease | Schwachman-Diamond...

United States
Aga Khan University
Boston University; World Health Organization

Completed

Community Case Management of the Severe Pneumonia With Oral Amoxicillin in Children 2-59 Months of Age

Severe Pneumonia

Pakistan
Philips Healthcare

Completed

The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III

Myocardial Infarction | Renal Failure | Cardiac Arrest | Severe Sepsis | Respiration Failure

United Kingdom

Search clinical trials for: severe renal failure

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