Search clinical trials for: sustained drug delivery implant

Total 265922 results

Glenn Jaffe
Bausch & Lomb Incorporated

Completed

A Study of a Sustained Release Fluocinolone Implant for Treatment of Central Retinal Vein Occlusion

Central Retinal Vein Occlusion

United States
Glenn Jaffe
Bausch & Lomb Incorporated

Completed

Fluocinolone Acetonide Implant for Retinal Vein Occlusion (RVO)

Retinal Vein Occlusion

United States
National Eye Institute (NEI)

Completed

Ganciclovir Implant Study for Cytomegalovirus Retinitis

HIV Infections | Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
Cancer Research Antwerp
Bayer; Veracyte, Inc.

Recruiting

Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers (THUNDER)

Prostate Cancer

Belgium
ZetrOZ, Inc.

Not yet recruiting

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

Arthritis | Osteo Arthritis Knee

United States
Hassan II University

Not yet recruiting

Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE) (INPEACE)

Cesarean Section Complications | Hypotension

Morocco
Drug Delivery Company, LLC DBA Akyso Pharmaceuticals
National Institute on Drug Abuse (NIDA); Laboratory Corporation of America; Cognitive...

Not yet recruiting

A Phase 1, Placebo-controlled, Single-Ascending-Dose, Study of BIOPIN 6 in Healthy Adults

Opioid Use Disorder
Spirair, Inc

Recruiting

Open-Label Study to Evaluate the Safety and Effectiveness of the Spirair Implant

Nasal Airway Obstruction | Nasal Septal Deviation

United States
Sociedad Espanola del Dolor

Recruiting

Effectiveness and Safety of Implantable Intrathecal Systems for Refractory Pain in Spain (INTRATHECAL-RENASED)

Refractory Pain

Spain
ZetrOZ, Inc.

Recruiting

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

Bone Fracture | Fresh Fracture

United States
Luye Pharma Group Ltd.

Not yet recruiting

Pharmacokinetics Pharmacodynamics and Safety of LY01022 in Patients With Prostate Cancer Compared With Zoladex® 10.8mg

Prostate Cancer

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Metastatic Sarcoma | Resectable Sarcoma | Recurrent Sarcoma

United States
London School of Hygiene and Tropical Medicine
Medical Research Council; Chiang Mai University

Not yet recruiting

Diabetes Self Management Education Programme in Thailand (DSMET)

Diabetes Mellitus, Type 2
Hoffmann-La Roche

Recruiting

Extension Study for the Port Delivery System With Ranibizumab (Portal) (Portal)

Neovascular Age-Related Macular Degeneration

Belgium, United States, United Kingdom, Italy, Argentina, Spain, Israel, Australia, Austria, Brazil, Germany, Switzerland, Taiwan, France
InCor Heart Institute
Ministry of Health, Brazil; Abbott Medical Devices

Recruiting

Amiodarone Against ICD Therapy in Chagas Cardiomyopathy for Primary Prevention of Death (CHAGASICS)

Chagas Cardiomyopathy | Non-sustained Ventricular Tachycardia | At Least 10 Points in Rassi Risk Score for Death

Brazil
NVT GmbH

Active, not recruiting

Investigation of the ALLEGRA THV System With a New Delivery System in Patients With Aortic Stenosis or Failed Surgical Bioprosthesis (EMPIRE)

Transcatheter Aortic Valve Implantation

Germany, Spain
Hoffmann-La Roche

Active, not recruiting

This Study Will Evaluate the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Participants With Diabetic Macular Edema Compared With Intravitreal Ranibizumab (Pagoda)

Diabetic Macular Edema

United States
AbbVie

Available

Expanded Access to Bimatoprost (Durysta)

Open-angle Glaucoma
Cerebral Therapeutics LLC

Terminated

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

Refractory Epilepsy

Israel, Australia
ZetrOZ, Inc.

Completed

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

Arthritis | Osteo Arthritis Knee

United States
Abbott Medical Devices

Active, not recruiting

Portico NG Approval Study

Symptomatic Severe Aortic Stenosis

United States, Australia, Denmark, Italy, United Kingdom
Oxular Limited

Active, not recruiting

Suprachoroidal Sustained-Release OXU-001 Compared to Intravitreal Ozurdex® in the Treatment of Diabetic Macular Edema (OXEYE)

Diabetic Macular Edema

United States, Puerto Rico
Medtronic Cardiac Rhythm and Heart Failure
United Therapeutics

Active, not recruiting

DelIVery for Pulmonary Arterial Hypertension (PAH) & Continued Support Study (DelIVery)

Pulmonary Arterial Hypertension

United States
Hoffmann-La Roche

Active, not recruiting

A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm (PAVILION)

Diabetic Retinopathy

United States, Puerto Rico
Alessa Therapeutics Inc.

Completed

A Study to Establish the Feasibility of Biolen for the Local Delivery of Bicalutamide in Patients With Prostate Cancer (Biolen-PC)

Lower Urinary Tract Symptoms | Prostate Adenocarcinoma

United States, Australia, New Zealand
ZetrOZ, Inc.

Completed

Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis (SAM)

Arthritis | Osteo Arthritis Knee

United States
Luye Pharma Group Ltd.

Completed

Efficacy and Safety of LY01005 in Patients With Breast Cancer Compared to ZOLADEX®

Breast Cancer

China
Luye Pharma Group Ltd.

Completed

Pharmacokinetics, Pharmacodynamics and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX®

Prostate Cancer

China
iSTAR Medical
International Drug Development Institute

Active, not recruiting

MINIject (MINI SO627) in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool

Glaucoma, Open-Angle Glaucoma Eye

India, Panama
iSTAR Medical

Completed

MINIject in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool

Glaucoma, Open-Angle | Glaucoma Eye

Panama, Colombia, India
Ripple Therapeutics Pty Ltd
Novotech (Australia) Pty Limited

Active, not recruiting

Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy

Diabetic Macular Oedema | Retinal Vein Occlusion With Macular Oedema

Australia, New Zealand, Hong Kong, Canada
Hoffmann-La Roche

Completed

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration (Archway)

Neovascular Age-Related Macular Degeneration

United States
Stanford University

Completed

Labor and Delivery Implant Insertion: A Randomized Controlled Trial (LADII)

Postpartum Contraception | Family Planning

United States
GOG Foundation
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride, Cisplatin, and Paclitaxel or Carboplatin and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer AJCC v7 | Stage IIIC Uterine Corpus Cancer AJCC v7 | Stage IVA Uterine Corpus Cancer AJCC v7 | Stage IVB Uterine Corpus Cancer AJCC v7

United States, Canada, Japan
Luye Pharma Group Ltd.

Completed

Efficacy and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX®

Prostate Cancer

China
Moens Maarten

Completed

Intrathecal Pump Refills at Home

Telemedicine | Intrathecal Drug Delivery | Implantable Pump

Belgium
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Home-based Delivery of the Contraceptive Implant in Postpartum Guatemalan Women

Postpartum

United States, Guatemala
Medtronic Cardiac Rhythm and Heart Failure
United Therapeutics

Withdrawn

Implantable System for Remodulin Post-Approval Study (ISR PAS)

Pulmonary Arterial Hypertension
Genentech, Inc.

Completed

Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration (LADDER)

Macular Degeneration

United States
Renishaw
Herantis Pharma Plc.

Active, not recruiting

Long-Term Follow-up Safety After DDS Implantation With/Without CDNF Infusions

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neuro-Degenerative Disease

Finland, Sweden
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney Function

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional... and other conditions

United States
Lahey Clinic

Terminated

Safety and Effectiveness of Ozurdex Steroid Implants for DME After Vitrectomy Surgery

Diabetic Macular Edema

United States
National Cancer Institute (NCI)

Terminated

Oblimersen Plus Doxorubicin and Docetaxel in Treating Patients With Metastatic or Locally Advanced Breast Cancer

Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer

United States
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL

Cataract

United States
Central Institute of Mental Health, Mannheim
University of Cologne

Completed

Cannabidiol as a Different Type of an Antipsychotic: Drug Delivery and Interaction Study (CBD-IS)

Schizophrenia

Germany
Universidad de Murcia

Completed

Implant Healing Abutment and Chlorhexidine (CHX-HA)

Periimplantitis

Spain
Medallion Therapeutics, Inc.

Completed

The Clinical Evaluation of Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic Pain

Chronic Pain | Cancers

United States
Medgenics Medical Israel Ltd.

Terminated

Safety and Biological Activity of InfraDure Biopump Secreting Sustained Interferon in HCV Patients

Hepatitis C
University Hospital, Clermont-Ferrand
Centre Leon Berard; Centre Jean Perrin; University Hospital, Grenoble; Hôpital... and other collaborators

Unknown

Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci (Etha-LOCK)

Catheter Related Blood Stream Infections | Intravenous Drug Delivery Systems | Lock Solution | Central Venous Catheter Infection | Coagulase-negative Staphylococci Infection

France
University Hospital, Toulouse

Completed

Comparison Between 25 µg Vaginal Misoprostol vs Slow Release Pessary PGE2 (CYTOPRO)

Delivery Uterine

France

Search clinical trials for: sustained drug delivery implant

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