Search clinical trials for: tacrolimus toxicity

Total 2847 results

University Health Network, Toronto
Paladin Labs Inc.

Not yet recruiting

Conversion of Maintenance Prograf to Envarsus in Liver Transplant Recipients

Liver Transplant Rejection | Immune System Suppression
Heleen Grootjans
Chiesi Farmaceutici S.p.A.

Recruiting

Trial Comparing Immediate Versus Extended Release Tacrolimus; Reducing Calcineurin Inhibitor Related Toxicity in Lung Transplantation Patients (REVOLUTION)

Lung Transplant; Complications

Netherlands
National Science Centre, Poland
Medical University of Warsaw

Recruiting

The New LC-MS/MS Method for Determination of Unbound Tacrolimus in Plasma (FreeTAC)

Kidney Transplant Rejection | Liver Transplant; Complications | Immunosuppression | Metabolism Medication Toxicity | Genetic Predisposition | Kidney Transplant; Complications | Liver Transplant Rejection

Poland
Sidney Kimmel Cancer Center at Thomas Jefferson...

Recruiting

A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing Toxicity

Hematopoietic and Lymphoid Cell Neoplasm

United States
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
Philipps University Marburg Medical Center

Active, not recruiting

Viral Load Guided Immunosuppression After Lung Transplantation (VIGILung)

Transplantation Lung

Austria, Germany
M.D. Anderson Cancer Center

Withdrawn

Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders

Stem Cell Transplantation

United States
University of Pittsburgh

Terminated

Pharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus Toxicity (Sirolimus)

Hypertension
M.D. Anderson Cancer Center
Sanofi

Completed

Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Leukemia | Transplantation Infection | Disorder Related to Bone Marrow Transplantation

United States
UDA Centro Nacional Hepato-Bilio-Pancreático
University Hospital, Limoges; Universidad de la Republica; INSERM UMR-S850, Limoges... and other collaborators

Terminated

Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients (3PIGREF)

End Stage Liver Disease | Diabetes | Toxicity | Rejection | Infection | Malignancy

Uruguay
Nationwide Children's Hospital

Terminated

A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell Disease

Sickle Cell Disease

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Massachusetts General Hospital; Brigham and...

Completed

Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma

Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
Janssen R&D Ireland

Completed

A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation

Hepatitis C, Chronic

Spain, Germany, Poland
Montefiore Medical Center

Terminated

Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity

Chronic Allograft Injury | Calcineurin Inhibitor Toxicity

United States
Emory University

Terminated

Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patients

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Myelofibrosis | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Acute Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Small Lymphocytic Lymphoma | Graft Versus Host Disease | Chronic Myelogenous Leukemia,...

United States
Stanford University

Completed

A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host Disease

Graft vs Host Disease

United States
Seoul National University Hospital

Completed

Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Disease

Graft vs Host Disease

Korea, Republic of
Thomas Jefferson University
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver Transplantation

Neurotoxicity | Renal Toxicity | Side Effects of Calcineurin Inhibitors | Hepatic Fibrosis on Biopsy | Post Transplant Diabetes

United States
Russian Academy of Medical Sciences
Russian Scientific Center of Surgery

Completed

Study Cyclosporine (CsA) Versus Tacrolimus (Tacro) After Campath Induction in Kidney Transplantation (RSCS-Campath)

Acute Graft Rejection | Chronic Allograft Nephropathy | Polyomavirus-related Transplant Nephropathy

Russian Federation
National Institute of Allergy and Infectious Diseases...
Cooperative Clinical Trials in Pediatric Transplantation

Terminated

Steroid Withdrawal in Pediatric Kidney Transplant Recipients

End-Stage Renal Disease

United States, Mexico
Nationwide Children's Hospital

Withdrawn

Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refractory High-Risk NBL.

Neuroblastoma

United States
Charite University, Berlin, Germany

Terminated

Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol (PROSKIN)

Kidney Transplantation | Skin Cancer

Germany
Irmandade Santa Casa de Misericórdia de Porto Alegre
Novartis

Completed

Effect of Switching to Certican® in Viremia of Hepatitis C Virus in Adult Renal Allograft Recipients (CONCERVIC)

Hepatitis C | Renal Allograft

Brazil
University of Oslo School of Pharmacy

Completed

Interaction Between Rimonabant and Cyclosporine and Tacrolimus (RIMONA-PILOT)

Renal Transplantation

Norway
Astellas Pharma Inc

Completed

Comparative Study of Modified Release (MR) Tacrolimus/Mycophenolate Mofetil (MMF) in de Novo Kidney Transplant Recipients

Kidney Transplantation

United States, Canada, Brazil
Shanghai University of Traditional Chinese Medicine

Unknown

Study on Single-nucleotide-polymorphism in Idiopathic Membranous Nephropathy

Idiopathic Membranous Nephropathy

China
Pirogov Russian National Research Medical University
Russian Academy of Medical Sciences

Unknown

Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection

End-Stage Renal Disease | Kidney Failure

Russian Federation
Samsung Medical Center

Completed

Randomized Trial of Cyclosporine and Tacrolimus Therapy With Steroid Withdrawal in Living-Donor Renal Transplantation

Kidney Transplantation | Living Donors

Korea, Republic of
Hoffmann-La Roche

Completed

Liver Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Sirolimus in Recipients of a Liver Transplant

Liver Transplantation

United States, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Conversion to Sirolimus vs. Continued Use of Calcineurin Inhibitors in Kidney Transplant Recipients

Renal Transplantation
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults

Hepatitis C

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloproliferative Disorders

Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases

United States
Pfizer

Completed

A Phase I Open-Label Study of the Effects of Tacrolimus and Cyclosporine on CP-690,555 in Healthy Volunteers

Healthy Volunteers

Singapore
Noordwest Ziekenhuisgroep
Borstkanker Onderzoek Groep; Comprehensive Cancer Centre The Netherlands; Dutch... and other collaborators

Not yet recruiting

Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects (eChemoCoach)

Breast Cancer | eHealth | Self Management | Symptom Monitoring
Odense University Hospital

Recruiting

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Quality of Life | Pleural Carcinomatosis | Chemotherapy Effect | Pleural Neoplasms | Chemotherapeutic Toxicity | Malignant Pleural Effusion | Pleural Cavity Effusion

Denmark
Nantes University Hospital

Not yet recruiting

Evaluation of a Range of Dermo-cosmetic Products to Treat Skin and Nail Toxicity Linked to Bispecific Anti-GPRC5D Bispecific Antibodies in Multiple Myeloma Patients". Myeloma". Descriptive Pilot Study (DELICATESSE)

Myeloma Multiple
Institut de cancérologie Strasbourg Europe
Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Recruiting

Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer (TNBC-RT2023)

Triple-negative Breast Cancer

France
Royal Marsden NHS Foundation Trust

Not yet recruiting

LATe TreatmENT Related Toxicity in Melanoma (LATENT) (LATENT)

Melanoma

United Kingdom
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
National Cancer Institute (NCI)

Not yet recruiting

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Carcinoma, Neuroendocrine | Tumor, Neuroendocrine | Tumors, Neuroendocrine | Neuroendocrine; Carcinoma | Small Cell; Receptors

United States
Air Force Military Medical University, China
First Affiliated Hospital Xi'an Jiaotong University; Shaanxi Provincial People... and other collaborators

Not yet recruiting

Efficacy and Safety of Tacrolimus in Combination With Ripertamab in the Initial Treatment of Patients With MCD

Minimal Change Disease
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium (RIVA-AP)

Anticholinergic Toxicity

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy (EROS3)

Locally Advanced Cervical Carcinoma
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
Eyestem Research Pvt. Ltd.

Not yet recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease
First Affiliated Hospital of Chengdu Medical College

Recruiting

Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis

Esophageal Cancer | Esophagitis | Radiation Toxicity

China
Universitair Ziekenhuis Brussel
University Ghent; Vrije Universiteit Brussel

Not yet recruiting

Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition. (PABTOX)

Breast Cancer | Body Weight | Chemotherapeutic Toxicity | Physical Inactivity | Chemotherapeutic Agent Toxicity | Paclitaxel Adverse Reaction

Belgium
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Assiut University

Not yet recruiting

Livertoxcicity in Acute Leukemia Patients During Chemotherapy Treatment

Liver Toxicity, Chemically-Induced
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine for Antimuscarinic Delirium (RIVA-AM)

Anticholinergic Toxicity

United States

Search clinical trials for: tacrolimus toxicity

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