Search clinical trials for: urate oxidase

Total 303 results

The Affiliated Hospital of Qingdao University

Recruiting

Tolerance, Pharmacokinetics / Pharmacodynamics (PK / PD) and Immunogenicity of Pegylated Uric Acid Oxidase for Injection in Healthy Adults and Hyperuricemia Volunteers

Hyperuricemia

China
M.D. Anderson Cancer Center

Recruiting

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Tumor Lysis Syndrome

United States
Shenyang Sunshine Pharmaceutical Co., LTD.

Recruiting

A Study to Determine the Safety, Tolerability, PK and Preliminary PD of SSS11 in Chinese Healthy Adult Volunteers

Gout

China
Allena Pharmaceuticals

Terminated

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease

Chronic Kidney Diseases | Hyperuricemia | Gout

United States
Allena Pharmaceuticals

Completed

An Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)

Chronic Kidney Diseases | Hyperuricemia | Gout

United States
Allena Pharmaceuticals
BDD Pharma Ltd

Completed

Scintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tablets

Hyperuricemia | Gout

United Kingdom
Allena Pharmaceuticals

Completed

ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers (SAD)

Hyperuricemia

United States
Allena Pharmaceuticals

Completed

Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase) (MAD)

Hyperuricemia | Gout

United States
M.D. Anderson Cancer Center
Sanofi

Completed

Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2

Lymphoma | Leukemia

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies

Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Burkitt Lymphoma | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Babylon University
Ministry of Health, Iraq

Completed

Effect of Oral Zinc Sulfate Supplementation on Enzymes of Urate Pathway

Infertility Unexplained

Iraq
John Sundy
Savient Pharmaceuticals

Completed

Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout

Gout

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Childhood Burkitt Lymphoma | Untreated Childhood Acute Lymphoblastic Leukemia | Stage I Childhood Large Cell Lymphoma | Stage I Childhood Small Noncleaved Cell Lymphoma | Stage II Childhood Large Cell Lymphoma | Stage II Childhood Small Noncleaved Cell Lymphoma and other conditions

United States
University of Florida

Completed

Lowering Serum Uric Acid to Prevent Acute Kidney Injury (RasbAKI)

Hyperuricemia

United States
Sanofi

Completed

Rasburicase for Hyperuricemia

Nutritional and Metabolic Diseases

Japan
Sanofi

Completed

Fasturtec TLS Treatment / Prophylysis

Tumor Lysis Syndrome

United States
TC Erciyes University

Not yet recruiting

The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction

Middle Ear Disease
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Tegoprazan Dual Therapy and Furazolidone-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication: A Prospective, Multicenter, Open-label, Randomized Controlled Clinical Study

Helicobacter Pylori Infection | Tegoprazan | Furazolidone
Hospital Universitari Vall d'Hebron Research Institute
DR Healthcare

Recruiting

Diamine Oxidase and Adverse Pregnancy Outcomes

Pregnancy Complications

Spain
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.

Gout Arthritis

China
Insel Gruppe AG, University Hospital Bern
Psychiatric University Hospital, Zurich

Recruiting

Molecular Imaging Study of Harmine/DMT: a Basic Research Approach (HaD-PET)

Neuropharmacological Investigation of Ayahuasca Constituents DMT and Harmine

Switzerland
Xijing Hospital of Digestive Diseases

Recruiting

Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication

the Eradication Rates of Helicobacter Pylori

China
Yongquan Shi

Recruiting

Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis Dyspepsia Helicobacter Pylori Infection Gastric Cancer Peptic Ulcer

China
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Dietary Supplementation of Diamine Oxidase to Improve Symptoms in Patients With IBS

Irritable Bowel Syndrome (IBS)

China
IRCCS Azienda Ospedaliero-Universitaria di Bologna
University of Bologna

Not yet recruiting

Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy (EDIPE)

Preeclampsia | Hypertensive Disorder of Pregnancy

Italy
Anna Stanhewicz, PhD

Recruiting

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

Oxidative Stress | Gestational Diabetes | Vascular Endothelial Function

United States
VA Office of Research and Development

Recruiting

Allopurinol Improves Heart Function in African Americans With Resistant Hypertension (RESIST)

Resistant Hypertension | Heart Failure Preserved Ejection Fraction

United States
Sultan Qaboos University

Not yet recruiting

Efficacy of Hydroxyzine for Patients With Panic Disorder

Panic Disorder
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy of Therapy Based on Fecal Molecular Antimicrobial Susceptibility Tests for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Shanton Pharma Co., Ltd.

Recruiting

Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.

Gout

United States, Puerto Rico
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Anhui Medical University; Beijing Tiantan... and other collaborators

Not yet recruiting

Efficacy and Safety of Rasagiline in Prodromal Parkinson's Disease

Parkinson Disease | Synucleinopathies | REM Sleep Behavior Disorder
LG Chem

Recruiting

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients (EURELIA2)

Hyperuricemia | Gout | Gout Flare | Tophi

United States
LG Chem

Recruiting

Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients (EURELIA1)

Hyperuricemia | Gout | Gout Flare | Tophi

United States
Liaocheng People's Hospital

Recruiting

Susceptibility-Guided Sequential Therapy for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
University Hospital, Strasbourg, France

Recruiting

Tolerance and Potential Synergistic Effect of the Combination of Intranasal Esketamine and Non-selective (MAOI) (ESKETAM)

Depression Anxiety Disorder

France
Chang Gung Memorial Hospital

Recruiting

Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty

Arthropathy of Knee Joint | Total Blood Loss

Taiwan
Lille Catholic University
Auckland University

Recruiting

Imagery as Biomarker of Gout (TIGER)

Hyperuricemia

France
The Third Xiangya Hospital of Central South University

Recruiting

Efficacy and Safety Study of Egg Yolk Antibody in Adjuvant Treatment of Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Xijing Hospital of Digestive Diseases

Recruiting

Vonoprazan Hp Dual or Triple Eradication Regimes

Helicobacter Pylori

China
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD (HCY)

Autosomal Dominant Polycystic Kidney Disease

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease | Infection

United States
Shanghai Zhongshan Hospital

Recruiting

Eradication Efficacy and Safety of Two Rescue Treatments for Helicobacter Pylori Infection

H. Pylori Infection

China
Shandong University

Recruiting

Helicobacter Pylori Rescue Treatment in Patients Allergic to Penicillin

Helicobacter Pylori Infection

China
Xiuli Zuo

Not yet recruiting

Efficacy and Safety of 14-day Concomitant Therapy for Difficult-to-Treat Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
wang xiaoyan

Recruiting

Differences in the Eradication of Helicobacter Pylori by Different Therapies

Helicobacter Pylori Infection

China
Shandong University

Not yet recruiting

Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy and Safety of Vonoprazan as First-line Treatment for Helicobacter Pylori Eradication

Helicobacter Pylori Infection

China
Massachusetts General Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout (TRUST)

Gout

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantation (Ana4CKD)

Chronic Kidney Disease | Gout | Renal Transplantation

France

Search clinical trials for: urate oxidase

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