Search clinical trials for: urokinase-type plasminogen activator

Total 614 results

Martin-Luther-Universität Halle-Wittenberg
German Breast Group

Unknown

6xFU/Epirubicin/Cyclophosphamide (FEC) Compared to 3xFEC-3xDocetaxel in High-risk Node-negative Breast Cancer Patients (NNBC3-Europe)

Breast Cancer

Germany
Dartmouth-Hitchcock Medical Center

Terminated

Phase I Study of Aprotinin in Advanced Breast Cancer

Metastatic Breast Cancer

United States
Karamanoğlu Mehmetbey University

Not yet recruiting

Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease

Periodontitis | Periodontal Diseases
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Kafrelsheikh University

Recruiting

Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction

Ischemic Stroke | Alteplase Adverse Reaction

Egypt
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China
The Second Hospital of Hebei Medical University

Recruiting

Treatment of Acute Ischemic Stroke With Rt-PA Combined With Edaravone Dexborneol (TASPE)

Acute Ischemic Stroke

China
Chinese University of Hong Kong
Queen Mary Hospital, Hong Kong; Princess Margaret Hospital, Canada; Tuen Mun... and other collaborators

Not yet recruiting

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC (DOAC-IVT)

CVA (Cerebrovascular Accident)

Hong Kong
The University of Texas Health Science Center,...
Baszucki Brain Research Fund

Recruiting

A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression

Bipolar Depression

United States
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
The First Affiliated Hospital of Zhengzhou University
Techpool Bio-Pharma Co., Ltd.

Recruiting

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Acute Ischemic Stroke

China
Kristina Svennerholm
Karolinska University Hospital; Sunderby Hospital; University Hospital, Linkoeping and other collaborators

Recruiting

Mechanical Thrombectomy With the FlowTriever Device in Acute Pulmonary Embolism - a Retrospective Analysis

Pulmonary Embolism

Sweden
M.D. Anderson Cancer Center

Recruiting

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

ALteplase in Patients With LOW NIHSS and Specified Disabling Deficits (ALLOW)

Thrombosis

China
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai Fifth People's Hospital; Shanghai Deji... and other collaborators

Recruiting

Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China (TTT-AIS CHINA)

Ischemic Stroke

China
Shionogi

Recruiting

A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke (REvive)

Acute Ischemic Stroke

Japan, Israel, United States, Australia, Hong Kong
ASST Fatebenefratelli Sacco
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; Careggi Hospital; University Hospital Tuebingen and other collaborators

Not yet recruiting

Clinical Phenotypes in Pericarditis: IL-1RA Antibodies and suPAR Levels (PERIPLO)

Pericarditis

Germany, Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Aspirin Combined With Clopidogrel Versus Intravenous Alteplase for Acute Minor Stroke (AGREE)

Ischemic Stroke

China
National University of Malaysia

Recruiting

Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic (PENTAD-FT)

Pleural Infection

Malaysia
Xuanwu Hospital, Beijing

Recruiting

Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)

Acute Ischemic Stroke | Arterial Thrombosis | Posterior Circulation Brain Infarction

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenzhen Hospital of Southern Medical University

Recruiting

Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy (PEARL)

Stroke, Acute Ischemic

China
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomédica; Instituto de Salud Carlos III

Not yet recruiting

CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2). (CHOICE2)

Stroke, Acute | Stroke, Acute Ischemic

Spain
Chinese University of Hong Kong

Not yet recruiting

Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE)

Pleural Infection

Hong Kong
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）

Acute Ischemic Stroke

China
Tianjin Huanhu Hospital

Recruiting

MR Imaging Selection for Endovascular Treatment in Acute Ischemic Stroke at 6 to 24 Hours (MIELS)

Endovascular Thrombectomy

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Application of tPA in Suprachoroidal and Subretinal Hemorrhage

Ocular Trauma

China
Xinqiao Hospital of Chongqing
Zhejiang University

Recruiting

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke (ADJUVANT)

Stroke, Acute Ischemic

China
Centre Hospitalier Sud Francilien

Recruiting

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes (DISTAL-IVT)

Acute Distal Vessel Occlusion Stroke

France
Sichuan Academy of Medical Sciences
Sichuan Provincial People's Hospital

Recruiting

Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke (BEST-BAO)

Thrombosis | Acute Ischemic Stroke | Basilar Artery Occlusion | Endovascular Treatment | Alteplase

China
Beijing Tiantan Hospital

Recruiting

Intra-arterial Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for Acute Large Vascular Occlusion After Successful Mechanical Thrombectomy Recanalization (ANGEL-TNK)

Ischemic Stroke, Acute

China
AO GENERIUM

Recruiting

Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction

ST Elevation Myocardial Infarction

Russian Federation
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
Ege University

Recruiting

Reduced Dose Thrombolytic in Intermediate/High Risk Pulmonary Thromboembolism

Pulmonary Embolism

Turkey
Hamilton Health Sciences Corporation

Recruiting

Use of Tissue Plasminogen Activator in the Clearance of Chronic Subdural Hematomas

Hematoma, Subdural | Fibrinolytic; Hemorrhage

Canada
Second Affiliated Hospital, School of Medicine,...

Recruiting

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Stroke, Acute Ischemic

China
Larissa University Hospital

Recruiting

The Role of Ischemia Modified Albumin in Patients With COVID-19

COVID-19

Greece
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
Saglik Bilimleri Universitesi

Recruiting

PAI-1 Levels and Predicting Covid-19 Patients' Prognosis

Covid-19 Positivity Confirmed With PCR Positivity in the Nasopharyngeal Swab | Symptomatic Covid -19 Positive Patients Who Require Hospitalization | Patients Who Did Not Vaccinate Against Covid-19 | Patients Among 20 to 90 Years of Age | Healthy Control Patients of the Same Age

Turkey
Assiut University

Not yet recruiting

The Prevalence and Associated Factors of Early Deterioration After Successful Recanalization in Acute Ischemic Stroke

Acute Stroke
University Hospital Tuebingen

Recruiting

Early Reperfusion Therapy With Intravenous Alteplase for Recovery of VISION in Acute Central Retinal Artery Occlusion (REVISION)

Central Retinal Artery Occlusion

Germany
Second Affiliated Hospital, School of Medicine,...
Shaoxing People's Hospital; Huizhou Municipal Central Hospital; The Second Affiliated... and other collaborators

Recruiting

24 Hours Treatment With Alteplase in Patients With Ischemic Stroke

Stroke

China
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom
Yonsei University

Recruiting

Prognostic Value of Soluble Urokinase-type Plasminogen Activator Receptor in Valvular Heart Disease

Severe Aortic Stenosis or Severe Aortic Regurgitation

Korea, Republic of
University of Melbourne
Professor Mark Parsons

Recruiting

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)

Ischemic Stroke

Australia
Assistance Publique - Hôpitaux de Paris
Canadian Institutes of Health Research (CIHR); Boehringer Ingelheim; Johannes... and other collaborators

Recruiting

Pulmonary Embolism International THrOmbolysis Study-3 (PEITHO-3)

Pulmonary Embolism

Netherlands, Spain, Belgium, Slovenia, France, Portugal, Austria, Canada, Poland, Switzerland, Germany, Italy, Romania, Serbia
University College, London

Recruiting

Nebulised Rt-PA for ARDS Due to COVID-19 (PACA)

COVID

United Kingdom
Assiut University

Not yet recruiting

Plasma Soluble Urokinase Plasminogen Activator Receptor and Behçet's Disease .

Behçet Disease
University of Aarhus

Recruiting

Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism (BETULA)

Pulmonary Embolism

Denmark
Radboud University Medical Center
UMC Utrecht; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Rare Bleeding Disorders in the Netherlands (RBIN)

Rare Bleeding Disorders

Netherlands
Population Health Research Institute
Heart and Stroke Foundation of Canada

Recruiting

Adjunctive, Low-dose tPA in Primary PCI for STEMI (STRIVE)

Myocardial Infarction | Percutaneous Coronary Intervention

Canada

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