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SAS115359: En 6-måneders undersøgelse for at vurdere sikkerheden og fordelene ved inhaleret fluticasonpropionat/salmeterol-kombination sammenlignet med inhaleret fluticasonpropionat ved behandling af unge og voksne (12 år og ældre) med astma. (AUSTRI)

2. august 2018 opdateret af: GlaxoSmithKline

SAS115359, en sikkerheds- og effektivitetsundersøgelse af inhaleret fluticasonpropionat/salmeterol-kombination versus inhaleret fluticasonpropionat til behandling af unge og voksne personer med astma

Formålet med denne undersøgelse er at vurdere, om risikoen for alvorlige astma-relaterede hændelser (astma-relaterede hospitalsindlæggelser, endotracheale intubationer og dødsfald) hos unge og voksne (12 år og ældre), der tager inhaleret fluticasonpropionat/salmeterol-kombination, er samme som dem, der tager inhaleret fluticasonpropionat alene.

ADVAIR™ og FLOVENT™ er varemærker tilhørende GlaxoSmithKline Group of Companies.

Studieoversigt

Status

Afsluttet

Betingelser

Astma

Intervention / Behandling

Detaljeret beskrivelse

Tilmeldingens fremskridt, opdateret årligt: Denne undersøgelse er afsluttet, og den endelige kliniske undersøgelsesrapport blev indsendt til FDA i januar 2016. Dette er den sidste opdatering, da denne undersøgelse er færdig.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

11751

Fase

Fase 4

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Argentina
- - Buenos Aires, Argentina, 1425
    - GSK Investigational Site
  - Buenos Aires, Argentina, 1406
    - GSK Investigational Site
  - Buenos Aires, Argentina, 1602
    - GSK Investigational Site
  - Ciudad Autónoma de Buenos Aires, Argentina, C1121ABE
    - GSK Investigational Site
  - La Plata, Argentina, B1902COS
    - GSK Investigational Site
  - Lanús, Argentina, B1824KAJ
    - GSK Investigational Site
  - Mendoza, Argentina, 5500
    - GSK Investigational Site
  - Rosario, Argentina, S2000BRH
    - GSK Investigational Site
- Buenos Aires
  - Derqui, Pilar, Buenos Aires, Argentina, B1629AHJ
    - GSK Investigational Site
  - Nueve de Julio, Buenos Aires, Argentina, B6500BWQ
    - GSK Investigational Site
  - San Martin, Buenos Aires, Argentina, 1650
    - GSK Investigational Site
- Entre Ríos
  - Concepcion del Uruguay, Entre Ríos, Argentina, 3260
    - GSK Investigational Site
  - Parana, Entre Ríos, Argentina, E3100BHK
    - GSK Investigational Site
- Santa Fe
  - Rosario, Santa Fe, Argentina, S2000JKR
    - GSK Investigational Site
- Tucumán
  - San Miguel de Tucuman, Tucumán, Argentina, 4000
    - GSK Investigational Site
Australien
- - Parkville, Australien, 3052
    - GSK Investigational Site
- New South Wales
  - Broadmeadow, New South Wales, Australien, 2292
    - GSK Investigational Site
  - Randwick, New South Wales, Australien, 2031
    - GSK Investigational Site
  - Westmead, New South Wales, Australien, 2145
    - GSK Investigational Site
- Queensland
  - Auchenflower, Queensland, Australien, 4066
    - GSK Investigational Site
  - Redcliffe, Queensland, Australien, 4020
    - GSK Investigational Site
  - Woolloongabba, Queensland, Australien, 4102
    - GSK Investigational Site
- South Australia
  - Bedford Park, South Australia, Australien, 5042
    - GSK Investigational Site
- Victoria
  - Clayton, Victoria, Australien, 3168
    - GSK Investigational Site
- Western Australia
  - Subiaco, Western Australia, Australien, 6008
    - GSK Investigational Site
Belgien
- - Brussels, Belgien, 1000
    - GSK Investigational Site
  - Bruxelles, Belgien, 1200
    - GSK Investigational Site
  - Bruxelles, Belgien, 1070
    - GSK Investigational Site
  - Hamois (Natoye), Belgien, 5360
    - GSK Investigational Site
  - Jambes, Belgien, 5100
    - GSK Investigational Site
  - Leuven, Belgien, 3000
    - GSK Investigational Site
  - Montigny-Le-Tilleul, Belgien, 6110
    - GSK Investigational Site
Bulgarien
- - Blagoevgrad, Bulgarien, 2700
    - GSK Investigational Site
  - Pazardjik, Bulgarien, 4400
    - GSK Investigational Site
  - Plovdiv, Bulgarien, 4000
    - GSK Investigational Site
  - Sliven, Bulgarien, 8800
    - GSK Investigational Site
  - Sofia, Bulgarien, 1606
    - GSK Investigational Site
  - Sofia, Bulgarien, 1000
    - GSK Investigational Site
  - Sofia, Bulgarien, 1463
    - GSK Investigational Site
  - Troyan, Bulgarien, 5600
    - GSK Investigational Site
  - Varna, Bulgarien, 9000
    - GSK Investigational Site
  - Veliko Tarnovo, Bulgarien, 5000
    - GSK Investigational Site
  - Vidin, Bulgarien, 3700
    - GSK Investigational Site
Canada
- Alberta
  - Edmonton, Alberta, Canada, T5A 4L8
    - GSK Investigational Site
  - Edmonton, Alberta, Canada, T5X 3N5
    - GSK Investigational Site
- British Columbia
  - Surrey, British Columbia, Canada, V4H 2H9
    - GSK Investigational Site
  - Surrey, British Columbia, Canada, V35 2N6
    - GSK Investigational Site
  - Victoria, British Columbia, Canada, V8V3N7
    - GSK Investigational Site
- Ontario
  - Brampton, Ontario, Canada, L6T3J1
    - GSK Investigational Site
  - Fort Erie, Ontario, Canada, L2A 1X3
    - GSK Investigational Site
  - Grimsby, Ontario, Canada, L3M 1P3
    - GSK Investigational Site
  - Kingston, Ontario, Canada, K7L 2V6
    - GSK Investigational Site
  - Mississauga, Ontario, Canada, L4T 4J2
    - GSK Investigational Site
  - Newmarket, Ontario, Canada, L3Y 5G8
    - GSK Investigational Site
  - Oshawa, Ontario, Canada, L1H 7K4
    - GSK Investigational Site
  - Toronto, Ontario, Canada, M5T 3A9
    - GSK Investigational Site
  - Windsor, Ontario, Canada, N8X 2G1
    - GSK Investigational Site
Chile
- - Santiago, Chile, 7560994
    - GSK Investigational Site
  - Valdivia, Chile, 5090146
    - GSK Investigational Site
  - Viña del Mar, Chile, 2570017
    - GSK Investigational Site
  - Viña del Mar, Chile, 2570017.
    - GSK Investigational Site
- Región De La Araucania
  - Temuco, Región De La Araucania, Chile, 4800798
    - GSK Investigational Site
- Valparaíso
  - Valparaiso, Valparaíso, Chile, 2341131
    - GSK Investigational Site
Colombia
- - Bogota, Colombia
    - GSK Investigational Site
  - Bucaramanga, Colombia
    - GSK Investigational Site
Danmark
- - Copenhagen, Danmark, 2400
    - GSK Investigational Site
  - Rosklide, Danmark, DK-4000
    - GSK Investigational Site
Den Russiske Føderation
- - Chelyabinsk, Den Russiske Føderation, 454021
    - GSK Investigational Site
  - Kemerovo, Den Russiske Føderation, 650000
    - GSK Investigational Site
  - Kemerovo, Den Russiske Føderation, 650002
    - GSK Investigational Site
  - Kirov, Den Russiske Føderation, 610027
    - GSK Investigational Site
  - Krasnodar, Den Russiske Føderation, 350063
    - GSK Investigational Site
  - Krasnoyarsk, Den Russiske Føderation, 660022
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 123182
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 125167
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 127018
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 125412
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 117593
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 115432
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 119121
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 125205
    - GSK Investigational Site
  - Moscow, Den Russiske Føderation, 110020
    - GSK Investigational Site
  - Novgorod, Den Russiske Føderation, 173008
    - GSK Investigational Site
  - Novosibirsk, Den Russiske Føderation, 630099
    - GSK Investigational Site
  - Novosibirsk, Den Russiske Føderation, 630087
    - GSK Investigational Site
  - Novosibirsk, Den Russiske Føderation, 630091
    - GSK Investigational Site
  - Novosibirsk, Den Russiske Føderation, 630051
    - GSK Investigational Site
  - Novosibirsk, Den Russiske Føderation, 630089
    - GSK Investigational Site
  - Orenburg, Den Russiske Føderation, 460018
    - GSK Investigational Site
  - Pyatigorsk, Den Russiske Føderation, 357538
    - GSK Investigational Site
  - Rostov-on-Don, Den Russiske Føderation, 344091
    - GSK Investigational Site
  - Ryazan, Den Russiske Føderation, 390026
    - GSK Investigational Site
  - Saint Petersburg, Den Russiske Føderation, 192212
    - GSK Investigational Site
  - Saint Petersburg, Den Russiske Føderation, 196657
    - GSK Investigational Site
  - Saint Petersburg, Den Russiske Føderation, 195067
    - GSK Investigational Site
  - Saint Petersburg, Den Russiske Føderation, 196084
    - GSK Investigational Site
  - Saint-Petersburg, Den Russiske Føderation, 194354
    - GSK Investigational Site
  - Saint-Petersburg, Den Russiske Føderation, 195112
    - GSK Investigational Site
  - Saratov, Den Russiske Føderation, 410018
    - GSK Investigational Site
  - St. Petersburg, Den Russiske Føderation, 197022
    - GSK Investigational Site
  - Tomsk, Den Russiske Føderation, 634063
    - GSK Investigational Site
  - Tomsk, Den Russiske Føderation, 634 050
    - GSK Investigational Site
  - Voronezh, Den Russiske Føderation, 394018
    - GSK Investigational Site
  - Yaroslavl, Den Russiske Føderation, 150003
    - GSK Investigational Site
Det Forenede Kongerige
- - Barry, Det Forenede Kongerige, CF63 4AR
    - GSK Investigational Site
  - Bexhill-on-Sea, Det Forenede Kongerige, TN40 1JJ
    - GSK Investigational Site
  - Chertsey, Surrey, Det Forenede Kongerige, KT16 0PZ
    - GSK Investigational Site
  - Glasgow, Det Forenede Kongerige, G12 0YN
    - GSK Investigational Site
  - Kent, Det Forenede Kongerige, CT5 3QU
    - GSK Investigational Site
  - Leicester, Det Forenede Kongerige, LE2 7LX
    - GSK Investigational Site
  - London, Det Forenede Kongerige, E2 9JX
    - GSK Investigational Site
  - London, Det Forenede Kongerige, E9 6SR
    - GSK Investigational Site
  - Merseyside, Det Forenede Kongerige, CH41 0DD
    - GSK Investigational Site
  - Penzance, Det Forenede Kongerige, TK19 7HX
    - GSK Investigational Site
  - Stoke on Trent, Det Forenede Kongerige, ST4 6QG
    - GSK Investigational Site
- Bedfordshire
  - Bedford, Bedfordshire, Det Forenede Kongerige, MK404AW
    - GSK Investigational Site
- Glamorgan
  - Cardiff, Glamorgan, Det Forenede Kongerige, CF5 4AE
    - GSK Investigational Site
- Greater Manchester
  - Manchester, Greater Manchester, Det Forenede Kongerige, M20 2RN
    - GSK Investigational Site
- Merseyside
  - Liverpool, Merseyside, Det Forenede Kongerige, L7 8XP
    - GSK Investigational Site
- Somerset
  - Bath, Somerset, Det Forenede Kongerige, BA2 1NH
    - GSK Investigational Site
- Sussex East
  - Brighton, Sussex East, Det Forenede Kongerige, BN2 5BE
    - GSK Investigational Site
Filippinerne
- - Dasmariñas, Cavite, Filippinerne, 4114
    - GSK Investigational Site
  - Davao, Filippinerne, 8000
    - GSK Investigational Site
  - Las Pinas, Filippinerne, 1470
    - GSK Investigational Site
  - Los Banos, Filippinerne, 4030
    - GSK Investigational Site
  - Pulilan, Filippinerne, 3005
    - GSK Investigational Site
  - Quezon City, Filippinerne, 1100
    - GSK Investigational Site
Forenede Stater
- Alabama
  - Athens, Alabama, Forenede Stater, 35611
    - GSK Investigational Site
  - Birmingham, Alabama, Forenede Stater, 35209
    - GSK Investigational Site
  - Birmingham, Alabama, Forenede Stater, 35233
    - GSK Investigational Site
  - Birmingham, Alabama, Forenede Stater, 35216
    - GSK Investigational Site
  - Florence, Alabama, Forenede Stater, 35630
    - GSK Investigational Site
  - Mobile, Alabama, Forenede Stater, 36608
    - GSK Investigational Site
  - Montgomery, Alabama, Forenede Stater, 36109
    - GSK Investigational Site
  - Pell City, Alabama, Forenede Stater, 35128
    - GSK Investigational Site
  - Scottsboro, Alabama, Forenede Stater, 35768
    - GSK Investigational Site
  - Toney, Alabama, Forenede Stater, 35773
    - GSK Investigational Site
  - Tuscaloosa, Alabama, Forenede Stater, 35401
    - GSK Investigational Site
- Arizona
  - Chandler, Arizona, Forenede Stater, 85224
    - GSK Investigational Site
  - Flagstaff, Arizona, Forenede Stater, 86001
    - GSK Investigational Site
  - Goodyear, Arizona, Forenede Stater, 85395
    - GSK Investigational Site
  - Green Valley, Arizona, Forenede Stater, 85614
    - GSK Investigational Site
  - Mesa, Arizona, Forenede Stater, 85206
    - GSK Investigational Site
  - Mesa, Arizona, Forenede Stater, 85203
    - GSK Investigational Site
  - Peoria, Arizona, Forenede Stater, 85381
    - GSK Investigational Site
  - Phoenix, Arizona, Forenede Stater, 85050
    - GSK Investigational Site
  - Phoenix, Arizona, Forenede Stater, 85023
    - GSK Investigational Site
  - Phoenix, Arizona, Forenede Stater, 85051
    - GSK Investigational Site
  - Phoenix, Arizona, Forenede Stater, 92120-4915
    - GSK Investigational Site
  - Scottsdale, Arizona, Forenede Stater, 85255
    - GSK Investigational Site
  - Sierra Vista, Arizona, Forenede Stater, 85635
    - GSK Investigational Site
  - Tucson, Arizona, Forenede Stater, 85704
    - GSK Investigational Site
- California
  - Anaheim, California, Forenede Stater, 92801
    - GSK Investigational Site
  - Anaheim, California, Forenede Stater, 92804
    - GSK Investigational Site
  - Bakersfield, California, Forenede Stater, 93301
    - GSK Investigational Site
  - Dinuba, California, Forenede Stater, 93618
    - GSK Investigational Site
  - Fresno, California, Forenede Stater, 93720
    - GSK Investigational Site
  - Granada Hills, California, Forenede Stater, 91344
    - GSK Investigational Site
  - Harbor City, California, Forenede Stater, 90710
    - GSK Investigational Site
  - Huntington Beach, California, Forenede Stater, 92647
    - GSK Investigational Site
  - Huntington Park, California, Forenede Stater, 90255
    - GSK Investigational Site
  - Lomita, California, Forenede Stater, 90717
    - GSK Investigational Site
  - Long Beach, California, Forenede Stater, 90806
    - GSK Investigational Site
  - Long Beach, California, Forenede Stater, 90813
    - GSK Investigational Site
  - Long Beach, California, Forenede Stater, 90807
    - GSK Investigational Site
  - Los Angeles, California, Forenede Stater, 90095
    - GSK Investigational Site
  - Los Angeles, California, Forenede Stater, 90057
    - GSK Investigational Site
  - Napa, California, Forenede Stater, 94558
    - GSK Investigational Site
  - Newport Beach, California, Forenede Stater, 92663
    - GSK Investigational Site
  - Oxnard, California, Forenede Stater, 93030
    - GSK Investigational Site
  - Paramount, California, Forenede Stater, 90723
    - GSK Investigational Site
  - Pismo Beach, California, Forenede Stater, 93449
    - GSK Investigational Site
  - Pomona, California, Forenede Stater, 91767
    - GSK Investigational Site
  - Rolling Hills Estates, California, Forenede Stater, 90274
    - GSK Investigational Site
  - Roseville, California, Forenede Stater, 95678
    - GSK Investigational Site
  - Sacramento, California, Forenede Stater, 95823
    - GSK Investigational Site
  - Sacramento, California, Forenede Stater, 95841
    - GSK Investigational Site
  - San Gabriel, California, Forenede Stater, 91776
    - GSK Investigational Site
  - San Jose, California, Forenede Stater, 95116
    - GSK Investigational Site
  - San Marcos, California, Forenede Stater, 92078-4081
    - GSK Investigational Site
  - San Marino, California, Forenede Stater, 91108
    - GSK Investigational Site
  - San Ramon, California, Forenede Stater, 94583
    - GSK Investigational Site
  - Santa Monica, California, Forenede Stater, 90404
    - GSK Investigational Site
  - Ventura, California, Forenede Stater, 93003
    - GSK Investigational Site
  - Vista, California, Forenede Stater, 92083
    - GSK Investigational Site
  - West Covina, California, Forenede Stater, 91790
    - GSK Investigational Site
  - West Sacramento, California, Forenede Stater, 95691
    - GSK Investigational Site
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80906
    - GSK Investigational Site
  - Colorado Springs, Colorado, Forenede Stater, 80922
    - GSK Investigational Site
  - Colorado Springs, Colorado, Forenede Stater, 80907
    - GSK Investigational Site
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - GSK Investigational Site
  - Denver, Colorado, Forenede Stater, 80206
    - GSK Investigational Site
  - Fort Collins, Colorado, Forenede Stater, 80538
    - GSK Investigational Site
  - Golden, Colorado, Forenede Stater, 80401
    - GSK Investigational Site
  - Thornton, Colorado, Forenede Stater, 80233
    - GSK Investigational Site
  - Wheat Ridge, Colorado, Forenede Stater, 80033
    - GSK Investigational Site
- Connecticut
  - Danbury, Connecticut, Forenede Stater, 06810
    - GSK Investigational Site
  - Milford, Connecticut, Forenede Stater, 06460
    - GSK Investigational Site
  - Waterbury, Connecticut, Forenede Stater, 06708
    - GSK Investigational Site
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20037
    - GSK Investigational Site
- Florida
  - Boynton Beach, Florida, Forenede Stater, 33437
    - GSK Investigational Site
  - Brandon, Florida, Forenede Stater, 33511
    - GSK Investigational Site
  - Clearwater, Florida, Forenede Stater, 33756
    - GSK Investigational Site
  - Clearwater, Florida, Forenede Stater, 33759
    - GSK Investigational Site
  - Cocoa, Florida, Forenede Stater, 32927
    - GSK Investigational Site
  - Coral Gables, Florida, Forenede Stater, 33134
    - GSK Investigational Site
  - Destin, Florida, Forenede Stater, 32541
    - GSK Investigational Site
  - Doral, Florida, Forenede Stater, 33172
    - GSK Investigational Site
  - Doral, Florida, Forenede Stater, 33166
    - GSK Investigational Site
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - GSK Investigational Site
  - Hialeah, Florida, Forenede Stater, 33016
    - GSK Investigational Site
  - Jacksonville, Florida, Forenede Stater, 32205
    - GSK Investigational Site
  - Jupiter, Florida, Forenede Stater, 33458
    - GSK Investigational Site
  - Maitland, Florida, Forenede Stater, 32751
    - GSK Investigational Site
  - Melbourne, Florida, Forenede Stater, 32935
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33125
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33156
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33126
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33175
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33165
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33155
    - GSK Investigational Site
  - Miami, Florida, Forenede Stater, 33015
    - GSK Investigational Site
  - New Port Richey, Florida, Forenede Stater, 34652
    - GSK Investigational Site
  - Orlando, Florida, Forenede Stater, 32806
    - GSK Investigational Site
  - Orlando, Florida, Forenede Stater, 32822
    - GSK Investigational Site
  - Orlando, Florida, Forenede Stater, 32811
    - GSK Investigational Site
  - Pensacola, Florida, Forenede Stater, 32514
    - GSK Investigational Site
  - Pinellas Park, Florida, Forenede Stater, 33781
    - GSK Investigational Site
  - Saint Cloud, Florida, Forenede Stater, 34769
    - GSK Investigational Site
  - Saint Petersburg, Florida, Forenede Stater, 33710
    - GSK Investigational Site
  - Saint Petersburg, Florida, Forenede Stater, 33707
    - GSK Investigational Site
  - Sarasota, Florida, Forenede Stater, 34233
    - GSK Investigational Site
  - Tallahassee, Florida, Forenede Stater, 32308
    - GSK Investigational Site
  - Tampa, Florida, Forenede Stater, 33613
    - GSK Investigational Site
  - Tampa, Florida, Forenede Stater, 33614
    - GSK Investigational Site
  - Tampa, Florida, Forenede Stater, 33606
    - GSK Investigational Site
  - Tampa, Florida, Forenede Stater, 33607
    - GSK Investigational Site
  - Trinity, Florida, Forenede Stater, 34655
    - GSK Investigational Site
  - Vero Beach, Florida, Forenede Stater, 32960
    - GSK Investigational Site
  - Wellington, Florida, Forenede Stater, 33414
    - GSK Investigational Site
  - Zephyrhills, Florida, Forenede Stater, 33540
    - GSK Investigational Site
- Georgia
  - Austell, Georgia, Forenede Stater, 30106
    - GSK Investigational Site
  - Columbus, Georgia, Forenede Stater, 31904
    - GSK Investigational Site
  - Decatur, Georgia, Forenede Stater, 30033
    - GSK Investigational Site
  - Gainesville, Georgia, Forenede Stater, 30501
    - GSK Investigational Site
  - Lawrenceville, Georgia, Forenede Stater, 30045
    - GSK Investigational Site
  - Lilburn, Georgia, Forenede Stater, 30047
    - GSK Investigational Site
  - Rincon, Georgia, Forenede Stater, 31326
    - GSK Investigational Site
  - Stockbridge, Georgia, Forenede Stater, 30281
    - GSK Investigational Site
  - Tucker, Georgia, Forenede Stater, 30084
    - GSK Investigational Site
- Illinois
  - Champaign, Illinois, Forenede Stater, 61820
    - GSK Investigational Site
  - Evergreen Park, Illinois, Forenede Stater, 60805
    - GSK Investigational Site
  - Glen Ellyn, Illinois, Forenede Stater, 60137
    - GSK Investigational Site
  - Glenview, Illinois, Forenede Stater, 60025
    - GSK Investigational Site
  - Normal, Illinois, Forenede Stater, 61761
    - GSK Investigational Site
  - Oak Lawn, Illinois, Forenede Stater, 60453
    - GSK Investigational Site
  - Oak Park, Illinois, Forenede Stater, 60302
    - GSK Investigational Site
  - Shiloh, Illinois, Forenede Stater, 62269
    - GSK Investigational Site
- Indiana
  - Avon, Indiana, Forenede Stater, 46123
    - GSK Investigational Site
  - Brownsburg, Indiana, Forenede Stater, 46112
    - GSK Investigational Site
  - Crown Point, Indiana, Forenede Stater, 46307
    - GSK Investigational Site
  - Franklin, Indiana, Forenede Stater, 46131
    - GSK Investigational Site
  - Greenfield, Indiana, Forenede Stater, 46140
    - GSK Investigational Site
  - Indianapolis, Indiana, Forenede Stater, 46256
    - GSK Investigational Site
  - Indianapolis, Indiana, Forenede Stater, 46208
    - GSK Investigational Site
  - Muncie, Indiana, Forenede Stater, 47304-5547
    - GSK Investigational Site
- Iowa
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - GSK Investigational Site
  - Iowa City, Iowa, Forenede Stater, 52242
    - GSK Investigational Site
  - West Des Moines, Iowa, Forenede Stater, 50265
    - GSK Investigational Site
- Kansas
  - Hutchinson, Kansas, Forenede Stater, 67502
    - GSK Investigational Site
  - Overland Park, Kansas, Forenede Stater, 66210
    - GSK Investigational Site
  - Overland Park, Kansas, Forenede Stater, 66215
    - GSK Investigational Site
- Kentucky
  - Hazard, Kentucky, Forenede Stater, 41701
    - GSK Investigational Site
  - Lexington, Kentucky, Forenede Stater, 40509
    - GSK Investigational Site
  - Lexington, Kentucky, Forenede Stater, 40504
    - GSK Investigational Site
  - Louisville, Kentucky, Forenede Stater, 40207
    - GSK Investigational Site
  - Louisville, Kentucky, Forenede Stater, 40291
    - GSK Investigational Site
- Louisiana
  - Alexandria, Louisiana, Forenede Stater, 71301
    - GSK Investigational Site
  - Covington, Louisiana, Forenede Stater, 70433
    - GSK Investigational Site
- Maine
  - Bangor, Maine, Forenede Stater, 04401
    - GSK Investigational Site
  - Portland, Maine, Forenede Stater, 4101
    - GSK Investigational Site
- Maryland
  - Annapolis, Maryland, Forenede Stater, 21401
    - GSK Investigational Site
  - Baltimore, Maryland, Forenede Stater, 21224
    - GSK Investigational Site
  - Columbia, Maryland, Forenede Stater, 21045
    - GSK Investigational Site
  - Hollywood, Maryland, Forenede Stater, 20636
    - GSK Investigational Site
  - Largo, Maryland, Forenede Stater, 20774
    - GSK Investigational Site
  - Silver Spring, Maryland, Forenede Stater, 20910
    - GSK Investigational Site
  - Towson, Maryland, Forenede Stater, 21204
    - GSK Investigational Site
  - Wheaton, Maryland, Forenede Stater, 20902
    - GSK Investigational Site
- Massachusetts
  - Fall River, Massachusetts, Forenede Stater, 02720
    - GSK Investigational Site
  - Hyannis, Massachusetts, Forenede Stater, 02601
    - GSK Investigational Site
- Michigan
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - GSK Investigational Site
  - Buckley, Michigan, Forenede Stater, 49620
    - GSK Investigational Site
  - Chelsea, Michigan, Forenede Stater, 48118
    - GSK Investigational Site
  - Chesterfield, Michigan, Forenede Stater, 48047
    - GSK Investigational Site
  - Detroit, Michigan, Forenede Stater, 48235
    - GSK Investigational Site
  - Detroit, Michigan, Forenede Stater, 48221
    - GSK Investigational Site
  - Fenton, Michigan, Forenede Stater, 48430
    - GSK Investigational Site
  - Interlochen, Michigan, Forenede Stater, 49643
    - GSK Investigational Site
  - Kalamazoo, Michigan, Forenede Stater, 49009
    - GSK Investigational Site
  - Niles, Michigan, Forenede Stater, 49120
    - GSK Investigational Site
  - Novi, Michigan, Forenede Stater, 48375
    - GSK Investigational Site
  - Stevensville, Michigan, Forenede Stater, 49127
    - GSK Investigational Site
- Minnesota
  - Chaska, Minnesota, Forenede Stater, 55318
    - GSK Investigational Site
  - Minneapolis, Minnesota, Forenede Stater, 55440
    - GSK Investigational Site
- Mississippi
  - Port Gibson, Mississippi, Forenede Stater, 39150
    - GSK Investigational Site
- Missouri
  - Kansas City, Missouri, Forenede Stater, 64114
    - GSK Investigational Site
  - Kansas City, Missouri, Forenede Stater, 64138
    - GSK Investigational Site
- Montana
  - Billings, Montana, Forenede Stater, 59101
    - GSK Investigational Site
  - Great Falls, Montana, Forenede Stater, 59405
    - GSK Investigational Site
- Nebraska
  - Bellevue, Nebraska, Forenede Stater, 68005
    - GSK Investigational Site
  - Lincoln, Nebraska, Forenede Stater, 68516
    - GSK Investigational Site
  - Lincoln, Nebraska, Forenede Stater, 02865
    - GSK Investigational Site
  - Lincoln, Nebraska, Forenede Stater, 68512
    - GSK Investigational Site
  - Omaha, Nebraska, Forenede Stater, 68130
    - GSK Investigational Site
- Nevada
  - Henderson, Nevada, Forenede Stater, 89014
    - GSK Investigational Site
  - Las Vegas, Nevada, Forenede Stater, 89106
    - GSK Investigational Site
  - Las Vegas, Nevada, Forenede Stater, 89107
    - GSK Investigational Site
  - Las Vegas, Nevada, Forenede Stater, 89183
    - GSK Investigational Site
- New Jersey
  - Atco, New Jersey, Forenede Stater, 08004
    - GSK Investigational Site
  - Brick, New Jersey, Forenede Stater, 08724
    - GSK Investigational Site
  - Edison, New Jersey, Forenede Stater, 08817
    - GSK Investigational Site
  - Edison, New Jersey, Forenede Stater, 08820
    - GSK Investigational Site
  - Elizabeth, New Jersey, Forenede Stater, 07202
    - GSK Investigational Site
  - Elizabeth, New Jersey, Forenede Stater, 07201
    - GSK Investigational Site
  - Freehold, New Jersey, Forenede Stater, 07728
    - GSK Investigational Site
  - Lumberton, New Jersey, Forenede Stater, 08048
    - GSK Investigational Site
  - Marlton, New Jersey, Forenede Stater, 08053
    - GSK Investigational Site
  - Ocean City, New Jersey, Forenede Stater, 07712
    - GSK Investigational Site
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - GSK Investigational Site
  - Trenton, New Jersey, Forenede Stater, 08611
    - GSK Investigational Site
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87131
    - GSK Investigational Site
- New York
  - Bronx, New York, Forenede Stater, 10457
    - GSK Investigational Site
  - Brooklyn, New York, Forenede Stater, 11215
    - GSK Investigational Site
  - Corning, New York, Forenede Stater, 14830
    - GSK Investigational Site
  - Endwell, New York, Forenede Stater, 13760
    - GSK Investigational Site
  - New Windsor, New York, Forenede Stater, 12553
    - GSK Investigational Site
  - New York, New York, Forenede Stater, 10017
    - GSK Investigational Site
  - New York, New York, Forenede Stater, 10022 11209
    - GSK Investigational Site
  - Newburgh, New York, Forenede Stater, 12550
    - GSK Investigational Site
  - Utica, New York, Forenede Stater, 13502
    - GSK Investigational Site
  - Westfield, New York, Forenede Stater, 14787
    - GSK Investigational Site
- North Carolina
  - Asheboro, North Carolina, Forenede Stater, 27203
    - GSK Investigational Site
  - Asheville, North Carolina, Forenede Stater, 28803
    - GSK Investigational Site
  - Calabash, North Carolina, Forenede Stater, 28467
    - GSK Investigational Site
  - Cary, North Carolina, Forenede Stater, 27518
    - GSK Investigational Site
  - Charlotte, North Carolina, Forenede Stater, 28207
    - GSK Investigational Site
  - Charlotte, North Carolina, Forenede Stater, 28209
    - GSK Investigational Site
  - Clyde, North Carolina, Forenede Stater, 28721
    - GSK Investigational Site
  - Lexington, North Carolina, Forenede Stater, 27295
    - GSK Investigational Site
  - Morganton, North Carolina, Forenede Stater, 28655
    - GSK Investigational Site
  - Shelby, North Carolina, Forenede Stater, 28152
    - GSK Investigational Site
  - Tabor City, North Carolina, Forenede Stater, 28463
    - GSK Investigational Site
  - Wilmington, North Carolina, Forenede Stater, 28401
    - GSK Investigational Site
- North Dakota
  - Fargo, North Dakota, Forenede Stater, 58103
    - GSK Investigational Site
  - Fargo, North Dakota, Forenede Stater, 58104
    - GSK Investigational Site
- Ohio
  - Centerville, Ohio, Forenede Stater, 45459
    - GSK Investigational Site
  - Cincinnati, Ohio, Forenede Stater, 45231
    - GSK Investigational Site
  - Cincinnati, Ohio, Forenede Stater, 45236
    - GSK Investigational Site
  - Cleveland, Ohio, Forenede Stater, 44130
    - GSK Investigational Site
  - Columbus, Ohio, Forenede Stater, 43215
    - GSK Investigational Site
  - Dayton, Ohio, Forenede Stater, 45406
    - GSK Investigational Site
  - Dayton, Ohio, Forenede Stater, 45459
    - GSK Investigational Site
  - Groveport, Ohio, Forenede Stater, 43125
    - GSK Investigational Site
  - Marion, Ohio, Forenede Stater, 43302
    - GSK Investigational Site
  - Middleburg Heights, Ohio, Forenede Stater, 44130
    - GSK Investigational Site
  - Shaker Heights, Ohio, Forenede Stater, 44120
    - GSK Investigational Site
  - Springfield, Ohio, Forenede Stater, 45504
    - GSK Investigational Site
  - Toledo, Ohio, Forenede Stater, 43606
    - GSK Investigational Site
  - Toledo, Ohio, Forenede Stater, 43617
    - GSK Investigational Site
  - Wheeling, Ohio, Forenede Stater, 26003
    - GSK Investigational Site
  - Youngstown, Ohio, Forenede Stater, 44501-1790
    - GSK Investigational Site
  - Zanesville, Ohio, Forenede Stater, 43701
    - GSK Investigational Site
- Oklahoma
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - GSK Investigational Site
  - Oklahoma City, Oklahoma, Forenede Stater, 73103
    - GSK Investigational Site
  - Oklahoma City, Oklahoma, Forenede Stater, 73112
    - GSK Investigational Site
- Oregon
  - Eugene, Oregon, Forenede Stater, 97401
    - GSK Investigational Site
  - Lake Oswego, Oregon, Forenede Stater, 97035
    - GSK Investigational Site
- Pennsylvania
  - Belle Vernon, Pennsylvania, Forenede Stater, 15012
    - GSK Investigational Site
  - Belle Vernon, Pennsylvania, Forenede Stater, 15025
    - GSK Investigational Site
  - Bensalem, Pennsylvania, Forenede Stater, 19020
    - GSK Investigational Site
  - Carnegie, Pennsylvania, Forenede Stater, 15106
    - GSK Investigational Site
  - Downingtown, Pennsylvania, Forenede Stater, 19335
    - GSK Investigational Site
  - Erie, Pennsylvania, Forenede Stater, 16508
    - GSK Investigational Site
  - Holland, Pennsylvania, Forenede Stater, 18966
    - GSK Investigational Site
  - Huntingdon Valley, Pennsylvania, Forenede Stater, 19006
    - GSK Investigational Site
  - Jenkintown, Pennsylvania, Forenede Stater, 19046
    - GSK Investigational Site
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - GSK Investigational Site
  - Latrobe, Pennsylvania, Forenede Stater, 15650
    - GSK Investigational Site
  - Philadelphia, Pennsylvania, Forenede Stater, 19152
    - GSK Investigational Site
  - Philadelphia, Pennsylvania, Forenede Stater, 19115
    - GSK Investigational Site
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - GSK Investigational Site
  - Pittsburgh, Pennsylvania, Forenede Stater, 15236
    - GSK Investigational Site
  - Pittsburgh, Pennsylvania, Forenede Stater, 15206
    - GSK Investigational Site
  - Scottdale, Pennsylvania, Forenede Stater, 15683
    - GSK Investigational Site
  - Shippensburg, Pennsylvania, Forenede Stater, 17257
    - GSK Investigational Site
  - Uniontown, Pennsylvania, Forenede Stater, 15401
    - GSK Investigational Site
- Rhode Island
  - East Greenwich, Rhode Island, Forenede Stater, 02818
    - GSK Investigational Site
  - Johnston, Rhode Island, Forenede Stater, 02919
    - GSK Investigational Site
  - Warwick, Rhode Island, Forenede Stater, 02888-3221
    - GSK Investigational Site
- South Carolina
  - Columbia, South Carolina, Forenede Stater, 29201
    - GSK Investigational Site
  - Florence, South Carolina, Forenede Stater, 29501
    - GSK Investigational Site
  - Greenville, South Carolina, Forenede Stater, 29615
    - GSK Investigational Site
  - Greenville, South Carolina, Forenede Stater, 29607
    - GSK Investigational Site
  - Greenwood, South Carolina, Forenede Stater, 29646
    - GSK Investigational Site
  - Greer, South Carolina, Forenede Stater, 29651
    - GSK Investigational Site
  - Union, South Carolina, Forenede Stater, 29379
    - GSK Investigational Site
- South Dakota
  - Dakota Dunes, South Dakota, Forenede Stater, 57049
    - GSK Investigational Site
  - Rapid City, South Dakota, Forenede Stater, 57702
    - GSK Investigational Site
  - Sioux Falls, South Dakota, Forenede Stater, 57108
    - GSK Investigational Site
- Tennessee
  - Chattanooga, Tennessee, Forenede Stater, 37421
    - GSK Investigational Site
  - Chattanooga, Tennessee, Forenede Stater, 37404
    - GSK Investigational Site
  - Chattanooga, Tennessee, Forenede Stater, 37411
    - GSK Investigational Site
  - Germantown, Tennessee, Forenede Stater, 38138
    - GSK Investigational Site
  - McKenzie, Tennessee, Forenede Stater, 38201
    - GSK Investigational Site
  - Shelbyville, Tennessee, Forenede Stater, 37160
    - GSK Investigational Site
- Texas
  - Arlington, Texas, Forenede Stater, 76018
    - GSK Investigational Site
  - Austin, Texas, Forenede Stater, 78731
    - GSK Investigational Site
  - Austin, Texas, Forenede Stater, 78758
    - GSK Investigational Site
  - Austin, Texas, Forenede Stater, 78759-8950
    - GSK Investigational Site
  - Corsicana, Texas, Forenede Stater, 75110
    - GSK Investigational Site
  - Dallas, Texas, Forenede Stater, 75246
    - GSK Investigational Site
  - Dallas, Texas, Forenede Stater, 75230
    - GSK Investigational Site
  - Dallas, Texas, Forenede Stater, 75225
    - GSK Investigational Site
  - Dallas, Texas, Forenede Stater, 75254
    - GSK Investigational Site
  - Duncanville, Texas, Forenede Stater, 75116
    - GSK Investigational Site
  - Gun Barrel City, Texas, Forenede Stater, 75156
    - GSK Investigational Site
  - Houston, Texas, Forenede Stater, 77055
    - GSK Investigational Site
  - Houston, Texas, Forenede Stater, 77034
    - GSK Investigational Site
  - Houston, Texas, Forenede Stater, 77043
    - GSK Investigational Site
  - Houston, Texas, Forenede Stater, 77077
    - GSK Investigational Site
  - Houston, Texas, Forenede Stater, 77079
    - GSK Investigational Site
  - Irving, Texas, Forenede Stater, 75061
    - GSK Investigational Site
  - Katy, Texas, Forenede Stater, 77450
    - GSK Investigational Site
  - Kerrville, Texas, Forenede Stater, 78028
    - GSK Investigational Site
  - Killeen, Texas, Forenede Stater, 76542
    - GSK Investigational Site
  - Kingwood, Texas, Forenede Stater, 77339
    - GSK Investigational Site
  - Lewisville, Texas, Forenede Stater, 75067
    - GSK Investigational Site
  - Lufkin, Texas, Forenede Stater, 75904
    - GSK Investigational Site
  - McKinney, Texas, Forenede Stater, 75071
    - GSK Investigational Site
  - Plano, Texas, Forenede Stater, 75075
    - GSK Investigational Site
  - Plano, Texas, Forenede Stater, 75024
    - GSK Investigational Site
  - San Antonio, Texas, Forenede Stater, 78229
    - GSK Investigational Site
  - San Antonio, Texas, Forenede Stater, 78258
    - GSK Investigational Site
  - San Antonio, Texas, Forenede Stater, 78233
    - GSK Investigational Site
  - San Antonio, Texas, Forenede Stater, 78251
    - GSK Investigational Site
  - San Antonio, Texas, Forenede Stater, 78238
    - GSK Investigational Site
  - Sugar Land, Texas, Forenede Stater, 77479
    - GSK Investigational Site
  - Tomball, Texas, Forenede Stater, 77375
    - GSK Investigational Site
  - Tyler, Texas, Forenede Stater, 75708
    - GSK Investigational Site
  - Waco, Texas, Forenede Stater, 76712
    - GSK Investigational Site
  - Waco, Texas, Forenede Stater, 76710
    - GSK Investigational Site
- Utah
  - Bountiful, Utah, Forenede Stater, 84010
    - GSK Investigational Site
  - Clinton, Utah, Forenede Stater, 84015
    - GSK Investigational Site
  - Layton, Utah, Forenede Stater, 84041
    - GSK Investigational Site
  - Midvale, Utah, Forenede Stater, 84047
    - GSK Investigational Site
  - Murray, Utah, Forenede Stater, 84107
    - GSK Investigational Site
  - West Jordan, Utah, Forenede Stater, 84088
    - GSK Investigational Site
- Vermont
  - Falls Church, Vermont, Forenede Stater, 22044
    - GSK Investigational Site
- Virginia
  - Alexandria, Virginia, Forenede Stater, 22304
    - GSK Investigational Site
  - Charlottesville, Virginia, Forenede Stater, 22902
    - GSK Investigational Site
  - Hampton, Virginia, Forenede Stater, 23666
    - GSK Investigational Site
  - Midlothian, Virginia, Forenede Stater, 23114
    - GSK Investigational Site
  - Midlothian, Virginia, Forenede Stater, 23113
    - GSK Investigational Site
  - Norfolk, Virginia, Forenede Stater, 23507
    - GSK Investigational Site
  - Richmond, Virginia, Forenede Stater, 23229
    - GSK Investigational Site
  - Richmond, Virginia, Forenede Stater, 23235
    - GSK Investigational Site
  - Richmond, Virginia, Forenede Stater, 23223
    - GSK Investigational Site
  - Richmond, Virginia, Forenede Stater, 23233
    - GSK Investigational Site
  - Suffolk, Virginia, Forenede Stater, 23435
    - GSK Investigational Site
  - Virginia Beach, Virginia, Forenede Stater, 23454
    - GSK Investigational Site
- Washington
  - Bellingham, Washington, Forenede Stater, 98225
    - GSK Investigational Site
  - Port Orchard, Washington, Forenede Stater, 98366
    - GSK Investigational Site
  - Puyallup, Washington, Forenede Stater, 98371
    - GSK Investigational Site
  - Spokane, Washington, Forenede Stater, 99204
    - GSK Investigational Site
- West Virginia
  - Morgantown, West Virginia, Forenede Stater, 26505
    - GSK Investigational Site
- Wisconsin
  - Madison, Wisconsin, Forenede Stater, 53792-9988
    - GSK Investigational Site
Indonesien
- - Denpasar, Indonesien, 80114
    - GSK Investigational Site
  - Depok Timur, Indonesien, 16411
    - GSK Investigational Site
  - Jakarta, Indonesien, 10430
    - GSK Investigational Site
  - Jakarta, Indonesien, 12430
    - GSK Investigational Site
  - Jakarta, Indonesien, 13230
    - GSK Investigational Site
  - Jakarta, Indonesien, 13630
    - GSK Investigational Site
  - Malang, Indonesien, 65100
    - GSK Investigational Site
  - Medan, Indonesien, 20111
    - GSK Investigational Site
  - Palembang, Indonesien, 30126
    - GSK Investigational Site
  - Semarang, Indonesien, 50242
    - GSK Investigational Site
  - Surakarta, Indonesien, 57126
    - GSK Investigational Site
Italien
- - Brescia, Italien, 25123
    - GSK Investigational Site
  - Messina, Italien, 98123
    - GSK Investigational Site
  - Milano, Italien, 20122
    - GSK Investigational Site
  - Milano, Italien, 20157
    - GSK Investigational Site
  - Milano, Italien, 20142
    - GSK Investigational Site
  - Monza, Italien, 20052
    - GSK Investigational Site
  - Roma, Italien, 00168
    - GSK Investigational Site
  - Sesto San Giovanni, Italien, 20099
    - GSK Investigational Site
- Emilia-Romagna
  - Parma, Emilia-Romagna, Italien, 43125
    - GSK Investigational Site
- Lazio
  - Roma, Lazio, Italien, 00165
    - GSK Investigational Site
  - Roma, Lazio, Italien, 00135
    - GSK Investigational Site
  - Roma, Lazio, Italien, 00157
    - GSK Investigational Site
- Liguria
  - Arenzano, Liguria, Italien, 16011
    - GSK Investigational Site
- Lombardia
  - Bergamo, Lombardia, Italien, 24128
    - GSK Investigational Site
  - Milano, Lombardia, Italien, 20157
    - GSK Investigational Site
  - Milano, Lombardia, Italien, 20162
    - GSK Investigational Site
  - Milano, Lombardia, Italien, 20129
    - GSK Investigational Site
  - Pavia, Lombardia, Italien, 27100
    - GSK Investigational Site
- Sicilia
  - Catania, Sicilia, Italien, 95125
    - GSK Investigational Site
  - Palermo, Sicilia, Italien, 90146
    - GSK Investigational Site
- Toscana
  - Firenze, Toscana, Italien, 50134
    - GSK Investigational Site
Korea, Republikken
- - Bucheon, Korea, Republikken, 420-717
    - GSK Investigational Site
  - Bucheon-si,, Korea, Republikken, 420-767
    - GSK Investigational Site
  - Busan, Korea, Republikken, 602-715
    - GSK Investigational Site
  - Chuncheon, Korea, Republikken, 200-722
    - GSK Investigational Site
  - Gwangju, Korea, Republikken, 501-757
    - GSK Investigational Site
  - Incheon, Korea, Republikken, 403-720
    - GSK Investigational Site
  - Incheon, Korea, Republikken, 402-751
    - GSK Investigational Site
  - Seoul, Korea, Republikken, 137-701
    - GSK Investigational Site
  - Seoul, Korea, Republikken, 110-744
    - GSK Investigational Site
  - Seoul, Korea, Republikken, 136-705
    - GSK Investigational Site
Kroatien
- - Cakovec, Kroatien, 40000
    - GSK Investigational Site
  - Senj, Kroatien, 53270
    - GSK Investigational Site
  - Zadar, Kroatien, 23000
    - GSK Investigational Site
  - Zagreb, Kroatien, 10000
    - GSK Investigational Site
Letland
- - Kuldiga, Letland, LV - 3301
    - GSK Investigational Site
  - Riga, Letland, LV 1003
    - GSK Investigational Site
  - Riga, Letland, LV1038
    - GSK Investigational Site
  - Riga, Letland, LV-1004
    - GSK Investigational Site
  - Tukums, Letland, LV - 3101
    - GSK Investigational Site
Litauen
- - Kaunas, Litauen, LT-50009
    - GSK Investigational Site
  - Kaunas, Litauen, LT-50128
    - GSK Investigational Site
  - Kaunas, Litauen, LT-47144
    - GSK Investigational Site
  - Kaunas, Litauen, LT-49456
    - GSK Investigational Site
  - Klaipeda, Litauen, LT-92288
    - GSK Investigational Site
  - Siauliai, Litauen, LT-76231
    - GSK Investigational Site
  - Utena, Litauen, LT-28151
    - GSK Investigational Site
  - Vilnius, Litauen, LT-08661
    - GSK Investigational Site
  - Vilnius, Litauen, LT-01117
    - GSK Investigational Site
  - Vilnius, Litauen, LT -10207
    - GSK Investigational Site
  - Vilnius, Litauen, LT-04338
    - GSK Investigational Site
  - Vilnius, Litauen, LT-08406
    - GSK Investigational Site
Malaysia
- - Alor Setar, Malaysia, 05460
    - GSK Investigational Site
  - Kota Bharu, Malaysia, 15886
    - GSK Investigational Site
  - Kuala Pilah, Malaysia, 72000
    - GSK Investigational Site
  - Selangor, Malaysia, 68100
    - GSK Investigational Site
  - Sungai Buloh, Malaysia, 47000
    - GSK Investigational Site
Mexico
- - Chihuahua, Mexico, 31020
    - GSK Investigational Site
  - Huixquilucan, Mexico, 52763
    - GSK Investigational Site
  - Monterrey, Mexico, 64710
    - GSK Investigational Site
  - Monterrey, Mexico, 64718
    - GSK Investigational Site
  - Zapopan, Mexico, 45128
    - GSK Investigational Site
- Aguascalientes
  - Aguascalientes, Ags, Aguascalientes, Mexico, 20127
    - GSK Investigational Site
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44280
    - GSK Investigational Site
Peru
- - Lima, Peru, Lima 1
    - GSK Investigational Site
  - Lima, Peru, Lima 18
    - GSK Investigational Site
  - Lima, Peru, L 33
    - GSK Investigational Site
  - San Borja, Lima, Peru, L36
    - GSK Investigational Site
Polen
- - Bielsko-Biala, Polen, 43-300
    - GSK Investigational Site
  - Brzesko, Polen, 32-800
    - GSK Investigational Site
  - Bydgoszcz, Polen, 85-168
    - GSK Investigational Site
  - Bystra, Polen, 43-360
    - GSK Investigational Site
  - Cieszyn, Polen, 43-400
    - GSK Investigational Site
  - Dębica, Polen, 39 - 200
    - GSK Investigational Site
  - Elblag, Polen, 82-300
    - GSK Investigational Site
  - Gdansk, Polen, 84-462
    - GSK Investigational Site
  - Gdanska, Polen, 80-433
    - GSK Investigational Site
  - Glucholazy, Polen, 41-340
    - GSK Investigational Site
  - Jelenia Gora, Polen, 58-500
    - GSK Investigational Site
  - Krakow, Polen, 31-202
    - GSK Investigational Site
  - Libiaz, Polen, 32-590
    - GSK Investigational Site
  - Lodz, Polen, 93-513
    - GSK Investigational Site
  - Lodz, Polen, 90-302
    - GSK Investigational Site
  - Lodz, Polen, 90-430
    - GSK Investigational Site
  - Lodz, Polen, 91-357
    - GSK Investigational Site
  - Lubin, Polen, 59-300
    - GSK Investigational Site
  - Lublin, Polen, 20-093
    - GSK Investigational Site
  - Olsztyn, Polen, 10-357
    - GSK Investigational Site
  - Poznan, Polen, 60-214
    - GSK Investigational Site
  - Radomsko, Polen, 97-500
    - GSK Investigational Site
  - Ruda Slaska, Polen, 41-709
    - GSK Investigational Site
  - Rudka, Polen, 05-320
    - GSK Investigational Site
  - Rzeszow, Polen, 35-241
    - GSK Investigational Site
  - Sandomierz, Polen, 27-600
    - GSK Investigational Site
  - Sopot, Polen, 81-741
    - GSK Investigational Site
  - Szczecin, Polen, 70-111
    - GSK Investigational Site
  - Warszawa, Polen, 01-138
    - GSK Investigational Site
  - Warszawa, Polen, 04-141
    - GSK Investigational Site
  - Warszawa, Polen, 01-157
    - GSK Investigational Site
  - Wodzislaw Slaski, Polen, 44-300
    - GSK Investigational Site
  - Wolomin, Polen, 05-200
    - GSK Investigational Site
  - Wroclaw, Polen, 54-239
    - GSK Investigational Site
  - Wroclaw, Polen, 53-301
    - GSK Investigational Site
  - Zabrze, Polen, 41-800
    - GSK Investigational Site
  - Zabrze, Polen, 41 - 800
    - GSK Investigational Site
  - Zgierz, Polen, 95-100
    - GSK Investigational Site
Rumænien
- - Brasov, Rumænien, 500074
    - GSK Investigational Site
  - Cluj-Napoca, Rumænien, 400371
    - GSK Investigational Site
  - Sibiu, Rumænien, 550166
    - GSK Investigational Site
Serbien
- - Belgrade, Serbien, 11000
    - GSK Investigational Site
  - Belgrade, Serbien, 11080
    - GSK Investigational Site
Slovakiet
- - Kosice, Slovakiet, 040 01
    - GSK Investigational Site
  - Kralovsky Chlmec, Slovakiet, 077 01
    - GSK Investigational Site
  - Levice, Slovakiet, 934 01
    - GSK Investigational Site
  - Martin, Slovakiet, 036 59
    - GSK Investigational Site
  - Sturovo, Slovakiet, 943 11
    - GSK Investigational Site
  - Trnava, Slovakiet, 917 01
    - GSK Investigational Site
Spanien
- - Barcelona, Spanien, 08036
    - GSK Investigational Site
  - Barcelona, Spanien, 08022
    - GSK Investigational Site
  - Barcelona, Spanien, 8036
    - GSK Investigational Site
  - Basurto/Bilbao, Spanien, 48013
    - GSK Investigational Site
  - Burgos, Spanien, 09005
    - GSK Investigational Site
  - Canet De Mar - Barcelona, Spanien, 08360
    - GSK Investigational Site
  - Cádiz, Spanien, 10009
    - GSK Investigational Site
  - Elche, Spanien, 12203
    - GSK Investigational Site
  - Illescas-Toledo, Spanien, 45004
    - GSK Investigational Site
  - La Coruña, Spanien, 15006
    - GSK Investigational Site
  - Lleida, Spanien, 25198
    - GSK Investigational Site
  - Madrid, Spanien, 28041
    - GSK Investigational Site
  - Madrid, Spanien, 28046
    - GSK Investigational Site
  - Madrid, Spanien, 28805
    - GSK Investigational Site
  - Majadahonda (Madrid), Spanien, 28222
    - GSK Investigational Site
  - Mataro, Spanien, 08303
    - GSK Investigational Site
  - Pozuelo De Alarcón/Madrid, Spanien, 28223
    - GSK Investigational Site
  - Sabadell (Barcelona), Spanien, 08208
    - GSK Investigational Site
  - Sagunto/Valencia, Spanien, 46520
    - GSK Investigational Site
  - Sant Boi de Llobregat, Spanien, 08830
    - GSK Investigational Site
  - Santiago de Compostela, Spanien, 15706
    - GSK Investigational Site
  - Tarrasa, Barcelona, Spanien, 08221
    - GSK Investigational Site
  - Torrelavega, Spanien, 39300
    - GSK Investigational Site
  - Valencia, Spanien, 46026
    - GSK Investigational Site
  - Valladolid, Spanien, 47012
    - GSK Investigational Site
  - Vic (Barcelona), Spanien, 08500
    - GSK Investigational Site
Sydafrika
- - Bellville, Sydafrika, 7531
    - GSK Investigational Site
  - Benoni, Sydafrika, 1501
    - GSK Investigational Site
  - Cape Town, Sydafrika, 7500
    - GSK Investigational Site
  - Cape Town, Sydafrika, 7700
    - GSK Investigational Site
  - Cape Town, Sydafrika, 7441
    - GSK Investigational Site
  - Cape Town, Sydafrika, 7570
    - GSK Investigational Site
  - Claremont, Sydafrika, 7708
    - GSK Investigational Site
  - Die Wilgers, Sydafrika, 0184
    - GSK Investigational Site
  - Durban, Sydafrika, 4001
    - GSK Investigational Site
  - Durban, Sydafrika, 4071
    - GSK Investigational Site
  - Gatesville, Sydafrika, 7764
    - GSK Investigational Site
  - Middelburg, Sydafrika, 1050
    - GSK Investigational Site
  - Pretoria, Sydafrika, 0002
    - GSK Investigational Site
  - Pretoria, Sydafrika, 0001
    - GSK Investigational Site
  - Somerset West, Sydafrika, 7130
    - GSK Investigational Site
  - Soweto, Sydafrika, 2013
    - GSK Investigational Site
  - Thabazimbi, Sydafrika
    - GSK Investigational Site
  - Welkom, Sydafrika, 9460
    - GSK Investigational Site
- Eastern Cape
  - Port Elizabeth, Eastern Cape, Sydafrika, 6014
    - GSK Investigational Site
- Gauteng
  - Cape Town, Gauteng, Sydafrika, 7505
    - GSK Investigational Site
  - Eloffsdal, Gauteng, Sydafrika, 0084
    - GSK Investigational Site
  - Krugersdorp, Gauteng, Sydafrika, 1752
    - GSK Investigational Site
  - Pretoria, Gauteng, Sydafrika, 0181
    - GSK Investigational Site
Taiwan
- - Kaohsiung, Taiwan, 833
    - GSK Investigational Site
  - Kaohsiung, Taiwan, 824
    - GSK Investigational Site
  - Keelung, Taiwan, 20401
    - GSK Investigational Site
  - Koahsiung, Taiwan, 81346
    - GSK Investigational Site
  - Putzu, Taiwan, 613
    - GSK Investigational Site
  - Taipei, Taiwan
    - GSK Investigational Site
  - Taipei, Taiwan, 220
    - GSK Investigational Site
  - Taipei, Taiwan, 106
    - GSK Investigational Site
  - Taipei, Taiwan, 115
    - GSK Investigational Site
Tjekkiet
- - Havlickuv brod, Tjekkiet, 580 01
    - GSK Investigational Site
  - Hlucin, Tjekkiet, 748 01
    - GSK Investigational Site
  - Jaromer, Tjekkiet, 551 01
    - GSK Investigational Site
  - Kyjov, Tjekkiet, 697 33
    - GSK Investigational Site
  - Plzen, Tjekkiet, 301 00
    - GSK Investigational Site
  - Plzen, Tjekkiet, 323 00
    - GSK Investigational Site
  - Praha 1, Tjekkiet, 110 00
    - GSK Investigational Site
  - Praha 13, Tjekkiet, 158 00
    - GSK Investigational Site
  - Praha 4, Tjekkiet, 140 00
    - GSK Investigational Site
  - Praha 6, Tjekkiet, 169 00
    - GSK Investigational Site
  - Praha 6, Tjekkiet, 163 00
    - GSK Investigational Site
  - Svitavy, Tjekkiet, 568 25
    - GSK Investigational Site
  - Tremosna, Tjekkiet, 330 11
    - GSK Investigational Site
Tyskland
- - Berlin, Tyskland, 13086
    - GSK Investigational Site
  - Berlin, Tyskland, 13353
    - GSK Investigational Site
  - Berlin, Tyskland, 13187
    - GSK Investigational Site
  - Berlin, Tyskland, 14050
    - GSK Investigational Site
  - Berlin, Tyskland, 10629
    - GSK Investigational Site
  - Berlin, Tyskland, 10787
    - GSK Investigational Site
  - Berlin, Tyskland, 12157
    - GSK Investigational Site
  - Berlin, Tyskland, 13156
    - GSK Investigational Site
  - Berlin, Tyskland, 12099
    - GSK Investigational Site
  - Berlin, Tyskland, 12165
    - GSK Investigational Site
  - Hamburg, Tyskland, 22143
    - GSK Investigational Site
  - Hamburg, Tyskland, 22335
    - GSK Investigational Site
  - Hamburg, Tyskland, 20354
    - GSK Investigational Site
  - Hamburg, Tyskland, 22767
    - GSK Investigational Site
- Baden-Wuerttemberg
  - Bruchsal, Baden-Wuerttemberg, Tyskland, 76646
    - GSK Investigational Site
  - Deggingen, Baden-Wuerttemberg, Tyskland, 73326
    - GSK Investigational Site
  - Mannheim, Baden-Wuerttemberg, Tyskland, 68161
    - GSK Investigational Site
  - Mannheim, Baden-Wuerttemberg, Tyskland, 68167
    - GSK Investigational Site
- Bayern
  - Aschaffenburg, Bayern, Tyskland, 63739
    - GSK Investigational Site
  - Augsburg, Bayern, Tyskland, 86150
    - GSK Investigational Site
  - Augsburg, Bayern, Tyskland, 86156
    - GSK Investigational Site
  - Bad Woerrishofen, Bayern, Tyskland, 86825
    - GSK Investigational Site
  - Feldkirchen, Bayern, Tyskland, 83620
    - GSK Investigational Site
  - Fuerth, Bayern, Tyskland, 90762
    - GSK Investigational Site
  - Gars Am Inn, Bayern, Tyskland, 83536
    - GSK Investigational Site
  - Georgensgmuend, Bayern, Tyskland, 91166
    - GSK Investigational Site
  - Grossheirath, Bayern, Tyskland, 96269
    - GSK Investigational Site
  - Hoechstadt, Bayern, Tyskland, 91315
    - GSK Investigational Site
  - Muenchen, Bayern, Tyskland, 80335
    - GSK Investigational Site
  - Muenchen, Bayern, Tyskland, 80337
    - GSK Investigational Site
  - Neuoetting, Bayern, Tyskland, 84524
    - GSK Investigational Site
  - Vilshofen, Bayern, Tyskland, 94474
    - GSK Investigational Site
  - Weissenhorn, Bayern, Tyskland, 89264
    - GSK Investigational Site
- Brandenburg
  - Potsdam, Brandenburg, Tyskland, 14478
    - GSK Investigational Site
  - Potsdam, Brandenburg, Tyskland, 14467
    - GSK Investigational Site
  - Rathenow, Brandenburg, Tyskland, 14712
    - GSK Investigational Site
- Hessen
  - Bad Arolsen, Hessen, Tyskland, 34454
    - GSK Investigational Site
  - Bensheim, Hessen, Tyskland, 64625
    - GSK Investigational Site
  - Frankenberg, Hessen, Tyskland, 35066
    - GSK Investigational Site
  - Frankfurt, Hessen, Tyskland, 60318
    - GSK Investigational Site
  - Frankfurt/Main, Hessen, Tyskland, 60320
    - GSK Investigational Site
  - Lahnau, Hessen, Tyskland, 35633
    - GSK Investigational Site
  - Offenbach, Hessen, Tyskland, 63071
    - GSK Investigational Site
  - Rodgau, Hessen, Tyskland, 63110
    - GSK Investigational Site
  - Ruesselsheim, Hessen, Tyskland, 65428
    - GSK Investigational Site
  - Schwalmstadt, Hessen, Tyskland, 34613
    - GSK Investigational Site
- Niedersachsen
  - Bad Pyrmont, Niedersachsen, Tyskland, 31812
    - GSK Investigational Site
  - Goettingen, Niedersachsen, Tyskland, 37081
    - GSK Investigational Site
  - Wolfsburg, Niedersachsen, Tyskland, 38448
    - GSK Investigational Site
- Nordrhein-Westfalen
  - Bad Lippspringe, Nordrhein-Westfalen, Tyskland, 33175
    - GSK Investigational Site
  - Beckum, Nordrhein-Westfalen, Tyskland, 59269
    - GSK Investigational Site
  - Bergisch Gladbach, Nordrhein-Westfalen, Tyskland, 51429
    - GSK Investigational Site
  - Bochum, Nordrhein-Westfalen, Tyskland, 44791
    - GSK Investigational Site
  - Bonn, Nordrhein-Westfalen, Tyskland, 53119
    - GSK Investigational Site
  - Bonn, Nordrhein-Westfalen, Tyskland, 53123
    - GSK Investigational Site
  - Detmold, Nordrhein-Westfalen, Tyskland, 32756
    - GSK Investigational Site
  - Engelskirchen, Nordrhein-Westfalen, Tyskland, 51766
    - GSK Investigational Site
  - Essen, Nordrhein-Westfalen, Tyskland, 45359
    - GSK Investigational Site
  - Essen, Nordrhein-Westfalen, Tyskland, 45136
    - GSK Investigational Site
  - Hagen, Nordrhein-Westfalen, Tyskland, 58089
    - GSK Investigational Site
  - Herne, Nordrhein-Westfalen, Tyskland, 44629
    - GSK Investigational Site
  - Kleve-Materborn, Nordrhein-Westfalen, Tyskland, 47533
    - GSK Investigational Site
  - Krefeld, Nordrhein-Westfalen, Tyskland, 47798
    - GSK Investigational Site
  - Muenster, Nordrhein-Westfalen, Tyskland, 48149
    - GSK Investigational Site
  - Neuss, Nordrhein-Westfalen, Tyskland, 41469
    - GSK Investigational Site
  - Ratingen, Nordrhein-Westfalen, Tyskland, 40878
    - GSK Investigational Site
  - Solingen, Nordrhein-Westfalen, Tyskland, 42651
    - GSK Investigational Site
  - Telgte, Nordrhein-Westfalen, Tyskland, 48291
    - GSK Investigational Site
  - Witten, Nordrhein-Westfalen, Tyskland, 58452
    - GSK Investigational Site
  - Wuppertal, Nordrhein-Westfalen, Tyskland, 42117
    - GSK Investigational Site
- Rheinland-Pfalz
  - Koblenz, Rheinland-Pfalz, Tyskland, 56068
    - GSK Investigational Site
  - Raubach, Rheinland-Pfalz, Tyskland, 56316
    - GSK Investigational Site
  - Rhaunen, Rheinland-Pfalz, Tyskland, 55624
    - GSK Investigational Site
- Saarland
  - Dillingen, Saarland, Tyskland, 66763
    - GSK Investigational Site
  - Saarbruecken, Saarland, Tyskland, 66111
    - GSK Investigational Site
- Sachsen
  - Auerbach, Sachsen, Tyskland, 08209
    - GSK Investigational Site
  - Boehlen, Sachsen, Tyskland, 04564
    - GSK Investigational Site
  - Delitzsch, Sachsen, Tyskland, 04509
    - GSK Investigational Site
  - Leipzig, Sachsen, Tyskland, 04357
    - GSK Investigational Site
  - Meissen, Sachsen, Tyskland, 1662
    - GSK Investigational Site
- Sachsen-Anhalt
  - Teuchern, Sachsen-Anhalt, Tyskland, 6682
    - GSK Investigational Site
  - Zerbst, Sachsen-Anhalt, Tyskland, 39261
    - GSK Investigational Site
- Schleswig-Holstein
  - Klappholz, Schleswig-Holstein, Tyskland, 24860
    - GSK Investigational Site
  - Reinfeld, Schleswig-Holstein, Tyskland, 23858
    - GSK Investigational Site
Ukraine
- - Cherkassy, Ukraine, 18009
    - GSK Investigational Site
  - Dnipropetrovsk, Ukraine, 49027
    - GSK Investigational Site
  - Dnipropetrovsk, Ukraine, 49101
    - GSK Investigational Site
  - Donetsk, Ukraine, 83059
    - GSK Investigational Site
  - Ivano-Frankivsk, Ukraine, 76008
    - GSK Investigational Site
  - Kharkiv, Ukraine, 61039
    - GSK Investigational Site
  - Kharkiv, Ukraine, 61002
    - GSK Investigational Site
  - Kharkiv, Ukraine, 61103
    - GSK Investigational Site
  - Kharkiv, Ukraine, 61157
    - GSK Investigational Site
  - Kharkiv, Ukraine, 61050
    - GSK Investigational Site
  - Kiev, Ukraine, 03680
    - GSK Investigational Site
  - Kryvyi Rih, Ukraine, 50082
    - GSK Investigational Site
  - Kyiv, Ukraine
    - GSK Investigational Site
  - Kyiv, Ukraine, 04201
    - GSK Investigational Site
  - Lviv, Ukraine, 79059
    - GSK Investigational Site
  - Odesa, Ukraine, 65117
    - GSK Investigational Site
  - Odesa, Ukraine, 65010
    - GSK Investigational Site
  - Odesa, Ukraine, 85038
    - GSK Investigational Site
  - Poltava, Ukraine, 36011
    - GSK Investigational Site
  - Simferopol, Ukraine, 95006
    - GSK Investigational Site
  - Sumy, Ukraine, 40022
    - GSK Investigational Site
  - Sumy, Ukraine, 40030
    - GSK Investigational Site
  - Sumy, Ukraine, 40031
    - GSK Investigational Site
  - Ternopil, Ukraine, 46000
    - GSK Investigational Site
  - Vinnytsia, Ukraine, 21018
    - GSK Investigational Site
  - Zaporizhzhia, Ukraine, 69600
    - GSK Investigational Site
  - Zaporizhzhya, Ukraine, 69001
    - GSK Investigational Site
  - Zhytomyr, Ukraine, 10002
    - GSK Investigational Site
Ungarn
- - Baja, Ungarn, 6500
    - GSK Investigational Site
  - Balassagyarmat, Ungarn, 2660
    - GSK Investigational Site
  - Budapest, Ungarn, 1089
    - GSK Investigational Site
  - Budapest, Ungarn, 1101
    - GSK Investigational Site
  - Budapest, Ungarn, 1117
    - GSK Investigational Site
  - Budapest, Ungarn, 1195
    - GSK Investigational Site
  - Budapest, Ungarn, 1221
    - GSK Investigational Site
  - Debrecen, Ungarn, 4026
    - GSK Investigational Site
  - Kaposvár, Ungarn, 7400
    - GSK Investigational Site
  - Komló, Ungarn, 7300
    - GSK Investigational Site
  - Mosonmagyaróvár, Ungarn, 9200
    - GSK Investigational Site
  - Nagykanizsa, Ungarn, 08800
    - GSK Investigational Site
  - Rackeve, Ungarn, 2300
    - GSK Investigational Site
  - Siófok, Ungarn, 8600
    - GSK Investigational Site
  - Szolnok, Ungarn, 5000
    - GSK Investigational Site
Østrig
- - Feldkirch, Østrig, 6800
    - GSK Investigational Site
  - Salzburg, Østrig, A-5020
    - GSK Investigational Site
  - Vienna, Østrig, A-1030
    - GSK Investigational Site
  - Wels, Østrig, 4600
    - GSK Investigational Site
  - Wien, Østrig, 1230
    - GSK Investigational Site

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

12 år og ældre (Barn, Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inklusionskriterier:

Afgivet samtykke til at deltage i undersøgelsen
Mand eller kvinde, 12 år og ældre
Klinisk diagnosticering af astma i mindst 1 år forud for randomiseringen
Klinik PEF på mere end eller lig med 50 % af den forventede normalværdi
Forsøgspersonen skal anvende en af de behandlinger for astma, der er anført i protokollen
Forsøgspersonen skal kunne udfylde astmakontrolspørgeskemaet, daglige spørgsmål om astma og bruge en DISKUS-inhalator
Forsøgsperson skal have mindst 1 astmaforværring i anamnesen, inklusive en af følgende i året før randomisering:
kræver behandling med systemiske kortikosteroider
en astma-relateret indlæggelse

Ekskluderingskriterier:

Anamnese med livstruende astma defineret for denne protokol som astmaepisode, der krævede intubation og/eller var forbundet med hyperkapnø, der krævede ikke-invasiv ventilatorstøtte
Samtidig luftvejssygdom bortset fra astma
Aktuelt bevis på, eller nogensinde blevet fortalt af en læge, at de har kronisk bronkitis, emfysem eller kronisk obstruktiv lungesygdom.
Træningsinduceret astma (som den eneste astma-relaterede diagnose), der ikke kræver daglig astmakontrolmedicin
Tilstedeværelse af en bakteriel eller viral luftvejsinfektion, der ikke er løst ved randomisering
En astmaforværring, der kræver systemiske kortikosteroider inden for 4 uger efter randomisering eller mere end 4 separate eksacerbationer i de 12 måneder forud for randomisering
Mere end 2 indlæggelser for behandling af astma i de 12 måneder forud for randomisering
Forsøgspersonen må ikke opfylde kriterierne for ustabil astmas sværhedsgrad som anført i protokollen
Potente cytokrom P450 3A4 (CYP3A4) hæmmere inden for de sidste 4 uger (f.eks. ritonavir, ketoconazol, itraconzol)
Graviditet, amning eller planlagt graviditet under undersøgelsen
Et Child in Care (CiC) er et barn, der er blevet sat under kontrol eller beskyttelse af en agentur, organisation, institution eller enhed af domstolene, regeringen eller et regeringsorgan, der handler i overensstemmelse med beføjelser, som er tildelt dem ved lov eller regulering.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Tredobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: ADVAIR 100/50mcg eksperimentelt lægemiddel	Medicin: ADVAIR 100/50mcg fluticasonpropionat/salmeterol kombination (100/50 mcg) to gange dagligt (AM og PM) i 6 måneder Andre navne: FSC 100/50
Eksperimentel: ADVAIR 250/50mcg eksperimentelt lægemiddel	Medicin: ADVAIR 250/50mcg fluticasonpropionat/salmeterol kombination (250/50 mcg) to gange dagligt (AM og PM) i 6 måneder Andre navne: FSC 250/50
Eksperimentel: ADVAIR 500/50mcg eksperimentelt lægemiddel	Medicin: ADVAIR 500/50mcg fluticasonpropionat/salmeterol kombination (500/50 mcg) to gange dagligt (AM og PM) i 6 måneder Andre navne: FSC 500/50
Aktiv komparator: FLOVENT 100mcg aktiv komparator	Medicin: FLOVENT 100mcg fluticasonpropionat (100) to gange dagligt (AM og PM) i 6 måneder Andre navne: FP 100
Aktiv komparator: FLOVENT 250mcg aktiv komparator	Medicin: FLOVENT 250mcg fluticasonpropionat (250mcg) to gange dagligt (AM og PM) i 6 måneder Andre navne: FP 250
Aktiv komparator: FLOVENT 500mcg aktiv komparator	Medicin: FLOVENT 500mcg fluticasonpropionat (500 mcg) to gange dagligt (AM og PM) i 6 måneder Andre navne: FP 500

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Antal deltagere, der oplever en hændelse i det sammensatte sikkerhedsendepunkt af alvorlige astmaudfald (astma-relateret hospitalsindlæggelse, astma-relateret endotracheal intubation eller astma-relateret død) Tidsramme: Fra dag 1 op til 26 uger	Sammensat endepunkt blev defineret som klinisk relevant endepunkt, der er konstrueret ud fra kombinationer af andre klinisk relevante endepunkter af alvorlige astmaudfald (dvs. astma-relateret hospitalsindlæggelse, astma-relateret endotracheal intubation eller astma-relateret død). Hospitalsindlæggelse blev defineret som et døgnophold eller et ≥24-timers ophold i et observationsområde på en akutmodtagelse eller anden tilsvarende facilitet. Sandsynligheden for at have hændelse blev opsummeret med Kaplan-Meier estimater. Hazard ratio, konfidensinterval og p-værdi er fra en stratificeret Cox proportional hazard model, der bruger randomiseringsstratum som stratificeringsfaktor. De 95 % CI, der er angivet i tabellen, er faktisk de 95.	Fra dag 1 op til 26 uger
Antal deltagere, der oplever mindst én astmaforværring Tidsramme: Fra dag 1 op til 26 uger	En astmaforværring er defineret som en forværring af astma, der kræver brug af systemiske kortikosteroider (tabletter, suspension eller injektion) i mindst tre dage eller et hospitalsindlæggelse eller akutmodtagelsesbesøg på grund af astma, der krævede systemiske kortikosteroider.	Fra dag 1 op til 26 uger

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Antal deltagere, der oplever mindst én astma-relateret hospitalsindlæggelse, endotracheal intubation og død Tidsramme: Fra dag 1 op til 26 uger	Hospitalsindlæggelse blev defineret som et døgnophold eller et ≥24-timers ophold i et observationsområde på en akutmodtagelse eller anden tilsvarende facilitet.	Fra dag 1 op til 26 uger
Antal deltagere, der trækker sig tilbage fra undersøgelsesbehandling på grund af astmaforværring Tidsramme: Fra dag 1 op til 26 uger	En astmaforværring er defineret som en forværring af astma, der kræver brug af systemiske kortikosteroider (tabletter, suspension eller injektion) i mindst tre dage eller et hospitalsindlæggelse eller akutmodtagelsesbesøg på grund af astma, der krævede systemiske kortikosteroider.	Fra dag 1 op til 26 uger
Gennemsnitlig redningsmedicin (Albuterol/Salbutamol) Bruges som sug pr. 24 timer Tidsramme: Fra dag 1 op til 26 uger	Redningsmedicin inkluderet albuterol/salbutamol brugt til at behandle akut astma blev rapporteret som sug pr. 24 timer over en periode på 6 måneder.	Fra dag 1 op til 26 uger

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

GlaxoSmithKline

Samarbejdspartnere

Parexel

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Hjælpsomme links

Researchers can use this site to request access to anonymised patient level data and/or supporting documents from clinical studies to conduct further research.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

18. november 2011

Primær færdiggørelse (Faktiske)

23. juni 2015

Studieafslutning (Faktiske)

23. juni 2015

Datoer for studieregistrering

Først indsendt

17. november 2011

Først indsendt, der opfyldte QC-kriterier

17. november 2011

Først opslået (Skøn)

21. november 2011

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

6. august 2018

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

2. august 2018

Sidst verificeret

1. august 2018

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

115359

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Data på patientniveau for denne undersøgelse vil blive gjort tilgængelige via www.clinicalstudydatarequest.com efter tidslinjerne og processen beskrevet på dette websted.

Studiedata/dokumenter

Studieprotokol
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register
Klinisk undersøgelsesrapport
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register
Datasætspecifikation
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register
Annoteret sagsbetænkningsformular
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register
Statistisk analyseplan
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register
Formular til informeret samtykke
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register
Individuelt deltagerdatasæt
Informations-id: 115359

Oplysningskommentarer: For yderligere information om denne undersøgelse henvises til GSK Clinical Study Register

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med ADVAIR 100/50mcg

GlaxoSmithKline
Parexel

Afsluttet

6-måneders sikkerheds- og fordelsundersøgelse af ADVAIR hos børn 4-11 år (VESTRI)

Astma

Forenede Stater, Australien, Spanien, Taiwan, Bulgarien, Den Russiske Føderation, Ukraine, Argentina, Tyskland, Peru, Polen, Sydafrika, Thailand, Korea, Republikken, Østrig, Belgien, Ungarn, Italien, Slovakiet, Malaysia, Tjekkiet, ... og mere
Eurofarma Laboratorios S.A.

Trukket tilbage

Klinisk undersøgelse, ikke-mindreværd mellem Noex® 50µg versus Busonid® 50µg i behandling af allergisk rhinitis (RINEX50)

Rhinitis, Allergisk, Flerårig

Brasilien
GlaxoSmithKline

Afsluttet

GSK BHR-undersøgelse (søn - Anden undersøgelse)

Astma

Forenede Stater, Bulgarien, Puerto Rico, Brasilien
Milton S. Hershey Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Afsluttet

Bedste afroamerikanske svar på astmamedicin (BARD)

Astma

Forenede Stater
GlaxoSmithKline

Afsluttet

En undersøgelse for at vurdere effektivitet og sikkerhed af forskellige doser af GW642444 hos personer med kronisk obstruktiv lungesygdom (KOL)

Lungesygdom, kronisk obstruktiv

Forenede Stater, Argentina, Estland, Canada, Chile, Tyskland, Peru, Filippinerne, Mexico, Korea, Republikken, Danmark, Den Russiske Føderation, Polen, Slovakiet
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Afsluttet

En bioækvivalensundersøgelse mellem Fluticasone Salmeterol Xinafoate vs. ADVAIR DISKUS® hos raske frivillige (BREATH-PK500)

Bioækvivalens

Grækenland
OrthoTrophix, Inc

Afsluttet

En undersøgelse, der evaluerer sikkerheden og effektiviteten af intraartikulære injektioner af TPX-100 hos personer med let til moderat patello-femoral slidgigt, der involverer begge knæ

Knæ slidgigt

Forenede Stater
Wageningen University
Friesland Campina

Ukendt

Postprandiale virkninger af mælkefedt (POEMI)

Ernæring | Metabolisme | Genomik | Postprandial metabolisme

Holland
University of Oxford
European and Developing Countries Clinical Trials Partnership (EDCTP); Institut...

Afsluttet

Sikkerhed, immunogenicitet og effektivitet af R21 Matrix-M hos 5-17 måneder gamle børn i Nanoro, Burkina Faso

Malaria, Falciparum

Burkina Faso
Sumitomo Pharma America, Inc.
BehaVR LLC

Afsluttet

En randomiseret, kontrolleret undersøgelse af to hjemme-selv-guidede virtual reality-interventioner for voksne med social angst. (BVR-100-102)

Social angstlidelse (SAD)

Forenede Stater

SAS115359: En 6-måneders undersøgelse for at vurdere sikkerheden og fordelene ved inhaleret fluticasonpropionat/salmeterol-kombination sammenlignet med inhaleret fluticasonpropionat ved behandling af unge og voksne (12 år og ældre) med astma. (AUSTRI)

SAS115359, en sikkerheds- og effektivitetsundersøgelse af inhaleret fluticasonpropionat/salmeterol-kombination versus inhaleret fluticasonpropionat til behandling af unge og voksne personer med astma

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Publikationer og nyttige links

Generelle publikationer

Hjælpsomme links

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Skøn)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Studiedata/dokumenter

Kliniske forsøg med ADVAIR 100/50mcg

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Georgia

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer