Internet-based Cognitive Behavioural Therapy for Cardiac Patients
1. oktober 2019 opdateret af: Martha Mackay, University of British Columbia
A Single-Centre, Open-Label Trial of Therapist-Assisted Internet-Based Cognitive Behaviour Therapy for Cardiac Patients With Depression
Our overall objective is to evaluate the efficacy of therapist-assisted, internet-based cognitive-behavioural therapy (iCBT) for depressed cardiac patients with respect to clinical outcomes, and the feasibility of the program.
Our primary outcome will be depression severity; secondary outcomes will be hospitalization for a cardiac cause, recurrent myocardial infarction or revascularization.
The study will inform a proposal to incorporate iCBT into the resources routinely available to cardiac patients following hospitalization for a cardiac event.
Studieoversigt
Status
Ukendt
Betingelser
Intervention / Behandling
Detaljeret beskrivelse
We are planning we are planning a single-arm, open label trial to evaluate the feasibility, acceptability and efficacy of iCBT among persistently depressed cardiac patients.
Cardiac patients will be recruited from inpatient units in a university-affiliated hospital and screened for depression at 4 and possibly 8 or 12 weeks following discharge.
Eligible patients will be enrolled in the iCBT program.Data regarding the primary outcome, improvement in depression severity, will be collected at completion of the intervention and at 8 weeks after completion.
In addition to depression severity data, we will also obtain other data related to clinical feasibility, such as treatment adherence and the acceptability of the intervention to patients.
Self-reported rates of hospital readmission or emergency visits for a cardiac cause will also be tracked.
Undersøgelsestype
Interventionel
Tilmelding (Forventet)
80
Fase
- Ikke anvendelig
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
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British Columbia
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Vancouver, British Columbia, Canada, V6Z1Y6
- Rekruttering
- St. Paul's Hospital, Providence Health Care
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Kontakt:
- Martha Mackay, PhD
- Telefonnummer: 63127 6046822344
- E-mail: mmackay@providencehealth.bc.ca
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-
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
19 år og ældre (Voksen, Ældre voksen)
Tager imod sunde frivillige
Ingen
Køn, der er berettiget til at studere
Alle
Beskrivelse
Inclusion Criteria:
- admitted to one of study units with any cardiac diagnosis OR cardiac procedure on this admission
- able to speak and read English
- able to provide informed consent and participate in therapy
- access to and ability to use a computer with internet access.
Between 4 and 12 weeks after discharge, consenting participants will be required to meet a further inclusion criterion of:
• current depressive symptoms of at least mild severity on 2 successive assessments, 4 weeks apart or a single assessment of mild symptoms at 12 weeks post-discharge.
Exclusion Criteria:
Applied at screening (and criteria 1 and 2 reapplied before enrolment):
- active suicidal ideation (since this requires immediate referral for intense psychiatric care)
- previous suicide attempt
- currently undergoing psychotherapy for depression
- receiving antidepressant medication that has been initiated or adjusted within previous 3 months
- concurrent psychiatric disorder, other than anxiety;
- self-reported substance misuse within past 6 months
- concurrent terminal illness
- clinical status interfering with ability to independently engage in iCBT.
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: N/A
- Interventionel model: Enkelt gruppeopgave
- Maskning: Ingen (Åben etiket)
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
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Eksperimentel: treatment
all participants will be assigned to the treatment, consisting of therapist-assisted iCBT.
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Designed for general clinical use (but not specifically cardiac patients), it consists of 5 online modules outlining cognitive-behavioural skills for depression, completed over 7-8 weeks.
The participants will be guided step-wise through the modules by the therapist.
Participants can work more or less at their own pace, but are expected to proceed to the next module within 1-2 weeks.
Because the content is identical for each participant, fidelity to the web-based component of the intervention is ensured.
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Depression Severity
Tidsramme: baseline, completion of treatment (average of 12 weeks), study completion (treatment completion + 8 weeks)
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change in severity of depression as measured by Patient Health Questionnaire-9
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baseline, completion of treatment (average of 12 weeks), study completion (treatment completion + 8 weeks)
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Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
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major adverse cardiac events
Tidsramme: completion of treatment, average of 8 weeks
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death, myocardial infarction, revascularization, hospitalization for a cardiac cause
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completion of treatment, average of 8 weeks
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Treatment Satisfaction Questionnaire
Tidsramme: completion of treatment, average of 8 weeks
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participants' satisfaction with treatment
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completion of treatment, average of 8 weeks
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Web-Based Program Usability Questionnaire
Tidsramme: completion of treatment, average of 8 weeks
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participants' experience with using the web-based program
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completion of treatment, average of 8 weeks
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Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Sponsor
Efterforskere
- Ledende efterforsker: Martha H Mackay, PhD, University of British Columbia
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Faktiske)
26. august 2019
Primær færdiggørelse (Forventet)
1. juni 2020
Studieafslutning (Forventet)
1. december 2020
Datoer for studieregistrering
Først indsendt
7. august 2019
Først indsendt, der opfyldte QC-kriterier
9. august 2019
Først opslået (Faktiske)
12. august 2019
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
3. oktober 2019
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
1. oktober 2019
Sidst verificeret
1. oktober 2019
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- H19-01695
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
JA
IPD-planbeskrivelse
We would share all of our de-identified, individual-level data with any credentialed researcher.
IPD-deling Understøttende informationstype
- STUDY_PROTOCOL
- SAP
- ICF
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