Telehealth-Based Exercise Program to Treat Fatigue in MS (MS-FIT)

Active Comparator: Brief telephone-based counseling

Telephone based counseling and instructional video

Käyttäytyminen: Brief telephone-based counseling

Brief telephone-based counseling using Motivational Interviewing and physical activity goal setting and problem solving

Placebo Comparator: Education Counseling

Mailed Physical Activity information and instructional video only

Muut: Education counseling

Mailed informational video of exercise programs

Fatigue

Modified Fatigue Inventory Scale (MFIS) at baseline, 3-month, 6-month MFIS consisted of 21 items, ranging from 0 (never) to 4 (almost always). The total score was 0 to 84.

Depression

Depression Module of the Patient Health Questionnaire (PHQ-9). 9-item self-report instrument designed to identify depressive symptoms consistent with criteria for major depressive episode in the Diagnostic and Statistical Manual for Mental Disorders, 4th Edition. Each item is rated over the last 2 weeks: 0 (not at all), 1 (several days), 2 (more than half the days), or 3 (nearly every day).

Total Score for 9 items = 27.

Physical Activity (Behavioral Target)

First item of the Godin Leisure-Time Exercise Questionnaire (GLTEQ). GLTEQ asks participants to indicated the number of days per week they engaged in strenuous (e.g., running), moderate (e.g., easy bicycling), and mild (e.g., easy walking) exercise activities for periods of 15 min or more. Total weekly frequency is then calculated using an algorithm that multiplies the frequency of activities by 9 (strenuous), 5 (moderate), or 3 (mild) metabolic equivalents and sums each to produce a total level of physical activity in MET/min per week.