A Comprehensive Care Programme for Patients With Chronic Obstructive Pulmonary Disease
Aperçu de l'étude
Statut
Les conditions
Intervention / Traitement
Description détaillée
Design: A randomised controlled trial of patients discharged from hospital after an episode of acute exacerbation of COPD. Patients will be randomised to the intervention arm or usual care group.
Setting: Tertiary University affiliated Hospital.
Interventions:
The Intervention group will receive a comprehensive programme which involves inputs from doctors, respiratory nurses and physiotherapists, providing an individualized care plan for each subject. The components in the programme will include optimization of medications, specialist physician follow up, nursing support in education, and physiotherapist support for pulmonary rehabilitation. Patients in the intervention group will also receive monthly telephone calls by a respiratory nurse for a period of 1 year to assess their conditions and answer their queries. Patients will also be followed up in the respiratory clinic by respiratory specialist once every 3 months for 1 year.
The control group will be managed as the usual care. The discharging physician will determine the patients' medication and follow up as in normal practice.
All patients will be asked to return for assessments (spirometry, 6 minute walk test, questionnaires on the severity of dyspnoea and quality of life) at baseline and 12 months
Main outcome measures: The primary endpoint is the hospital readmission rate and the secondary endpoints are the quality of life, mortality, lung function and exercise capacity of the patients.
Type d'étude
Inscription (Réel)
Phase
- N'est pas applicable
Contacts et emplacements
Lieux d'étude
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Hong Kong, Hong Kong
- The Chinese University of Hong Kong
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Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
Accepte les volontaires sains
Sexes éligibles pour l'étude
La description
Inclusion Criteria:
- Patients who are admitted to the Prince of Wales Hospital with AECOPD will be screened for this study.
- Patients with age over 40 years
Exclusion Criteria:
- Patients with asthma
- Patients unable to provide informed consent
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
- Objectif principal: Traitement
- Répartition: Randomisé
- Modèle interventionnel: Affectation parallèle
- Masquage: Seul
Armes et Interventions
Groupe de participants / Bras |
Intervention / Traitement |
|---|---|
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Comparateur actif: comprehensive care programme
Comprehensive care involving multidisciplinary input.
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Intervention group:
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Aucune intervention: Control group
Control arm with usual care
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Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
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Hospital Readmission
Délai: 12 months
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To investigate the effectiveness of a comprehensive care programme in reducing hospital admission in COPD patients who have been discharged from hospital for an episode of AECOPD.
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12 months
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Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
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Quality of Life
Délai: 12 months
|
Measured by change in St. George Respiratory Questionnaire (SGRQ) total score from baseline to 12 month.
SGRQ total score ranged from 0-100.
The change was calculated by the 12 month SGRQ total score minus the baseline value.
Negative values indicated improvement in quality of life.
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12 months
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Mortality
Délai: 12 months
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From contacting the patient/their family and hospital record retrieval.
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12 months
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Lung Function
Délai: 12 months
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Measurement of change of spirometry (FEV1 % predicted) from baseline to 12 month.
The range is from 0% to 100%.
The change was calculated by 12 month value minus the baseline value.
Positive value indicated improvement in lung function.
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12 months
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Exercise Capacity
Délai: 12 month
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Exercise capacity was measured by change in 6 minutes walk test distance from baseline to 12 month.
6 minute walk test is the distance that the patient can walk over 6 minutes and it can range to 0 meters to few hundred meters.
This was calculated by the 12 month 6 minutes walk test distance minus that of the baseline.
Positive values indicated improvement in exercise capacity.
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12 month
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Collaborateurs et enquêteurs
Parrainer
Les enquêteurs
- Directeur d'études: David S Hui, MD, Chinese University of Hong Kong
Publications et liens utiles
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude
Achèvement primaire (Réel)
Achèvement de l'étude (Réel)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Estimation)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- Resp/Ko/2010/001
Plan pour les données individuelles des participants (IPD)
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