Evidence-based recommendations for the management of anterior cruciate ligament (ACL) rupture

Stephanie R Filbay, Hege Grindem, Stephanie R Filbay, Hege Grindem

Abstract

Anterior cruciate ligament (ACL) rupture occurs most commonly in young and active individuals and can have negative long-term physical and psychological impacts. The diagnosis is made with a combination of patient's history, clinical examination, and, if appropriate, magnetic resonance imaging. The objectives of management are to restore knee function, address psychological barriers to activity participation, prevent further injury and osteoarthritis, and optimize long-term quality of life. The three main treatment options for ACL rupture are (1) rehabilitation as first-line treatment (followed by ACL reconstruction (ACLR) in patients, who develop functional instability), (2) ACLR and post-operative rehabilitation as the first-line treatment, and (3) pre-operative rehabilitation followed by ACLR and post-operative rehabilitation. We provide practical recommendations for informing and discussing management options with patients, and describe patient-related factors associated with a worse ACL-rupture outcome. Finally, we define evidence-based rehabilitation and present phase-specific rehabilitation recommendations and criteria to inform return to sport decisions.

Keywords: Anterior cruciate ligament reconstruction; Clinical recommendations; Evidence-based practice; Knee osteoarthritis; Patient-centered care; Quality of life; Rehabilitation; Return to sport.

Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

References

    1. Griffin L.Y., Albohm M.J., Arendt E.A., Bahr R., Beynnon B.D., DeMaio M. Understanding and preventing noncontact anterior cruciate ligament injuries: a review of the Hunt Valley II meeting, January 2005. Am J Sports Med. 2006;34(9):1512–1532.
    1. Logerstedt D.S., Snyder-Mackler L., Ritter R.C., Axe M.J., Godges J.J. Knee stability and movement coordination impairments: knee ligament sprain. J Orthop Sports Phys Ther. 2010;40(4):A1–A37.
    1. Benjaminse A., Gokeler A., van der Schans C.P. Clinical diagnosis of an anterior cruciate ligament rupture: a meta-analysis. J Orthop Sports Phys Ther. 2006;36(5):267–288.
    1. Frobell R.B., Lohmander L.S., Roos H.P. Acute rotational trauma to the knee: poor agreement between clinical assessment and magnetic resonance imaging findings. Scand J Med Sci Sports. 2007;17(2):109–114.
    1. Van Dyck P., Vanhoenacker F.M., Lambrecht V., Wouters K., Gielen J.L., Dossche L. Prospective comparison of 1.5 and 3.0-T MRI for evaluating the knee menisci and ACL. J Bone Joint Surg Am. 2013;95(10):916–924.
    1. Bachmann L.M., Haberzeth S., Steurer J., ter Riet G. The accuracy of the Ottawa knee rule to rule out knee fractures: a systematic review. Ann Intern Med. 2004;140(2):121–124.
    1. Abbasi D., May M.M., Wall E.J., Chan G., Parikh S.N. MRI findings in adolescent patients with acute traumatic knee hemarthrosis. J Pediatr Orthop. 2012;32(8):760–764.
    1. Stiell I.G., Greenberg G.H., Wells G.A., McKnight R.D., Cwinn A.A., Cacciotti T. Derivation of a decision rule for the use of radiography in acute knee injuries. Ann Emerg Med. 1995;26(4):405–413.
    1. Filbay S.R., Culvenor A.G., Ackerman I.N., Russell T.G., CK M. Quality of life in anterior cruciate ligament-deficient individuals: a systematic review and meta-analysis. Br J Sports Med. 2015;49(16):1033–1041.
    1. Filbay S.R., Ackerman I.N., Russell T.G., Macri E.M., Crossley K.M. Health-related quality of life after anterior cruciate ligament reconstruction: a systematic review. Am J Sports Med. 2014;42(5):1247–1255.
    1. Øiestad B.E., Engebretsen L., Storheim K., Risberg M.A. Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med. 2009;37(7):1434–1443.
    1. Ardern C.L., Taylor N., Feller J., Webster K. A systematic review of the psychological factors associated with returning to sport following injury. Br J Sports Med. 2012 Nov;47(17):1120–1126. Epub 2012 Oct 13.
    1. Ardern C.L., Taylor N.F., Feller J.A., Webster K.E. Fifty-five per cent return to competitive sport following anterior cruciate ligament reconstruction surgery: an updated systematic review and meta-analysis including aspects of physical functioning and contextual factors. Br J Sports Med. 2014;48(21):1543–1552.
    1. Kvist J., Ek A., Sporrstedt K., Good L. Fear of re-injury: a hindrance for returning to sports after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2005;13(5):393–397.
    1. Webster K.E., Feller J.A. Exploring the high reinjury rate in younger patients undergoing anterior cruciate ligament reconstruction. Am J Sports Med. 2016;44(11):2827–2832.
    1. Gifstad T., Drogset J.O., Viset A., Grøntvedt T., Hortemo G.S. Inferior results after revision ACL reconstructions: a comparison with primary ACL reconstructions. Knee Surg Sports Traumatol Arthrosc. 2012:1–8.
    1. Lind M., Menhert F., Pedersen A.B. Incidence and outcome after revision anterior cruciate ligament reconstruction: results from the Danish registry for knee ligament reconstructions. Am J Sports Med. 2012;40(7):1551–1557.
    1. Filbay S.R., Ackerman I.N., Russell T.G., Crossley K.M. Return to sport matters—longer-term quality of life after ACL reconstruction in people with knee difficulties. Scand J Med Sci Sports. 2017;27(5):514–524.
    1. Filbay S.R., Crossley K.M., Ackerman I.N. Activity preferences, lifestyle modifications and re-injury fears influence longer-term quality of life in people with knee symptoms following anterior cruciate ligament reconstruction: a qualitative study. J Physiother. 2016 Apr;62(2):103–110. Epub 2016 Mar 16.
    1. Lentz T.A., Zeppieri G., Jr., Tillman S.M., Indelicato P.A., Moser M.W., George S.Z. Return to preinjury sports participation following anterior cruciate ligament reconstruction: contributions of demographic, knee impairment, and self-report measures. J Orthop Sports Phys Ther. 2012;42(11):893–901.
    1. Grindem H., Snyder-Mackler L., Moksnes H., Engebretsen L., Risberg M.A. Simple decision rules can reduce reinjury risk by 84% after ACL reconstruction: the Delaware-Oslo ACL cohort study. Br J Sports Med. 2016;50(13):804–808.
    1. Kyritsis P., Bahr R., Landreau P., Miladi R., Witvrouw E. Likelihood of ACL graft rupture: not meeting six clinical discharge criteria before return to sport is associated with a four times greater risk of rupture. Br J Sports Med. 2016;50(15):946–951.
    1. Sugimoto D., Myer G.D., Foss K.D., Hewett T.E. Dosage effects of neuromuscular training intervention to reduce anterior cruciate ligament injuries in female athletes: meta- and sub-group analyses. Sports Med. 2014;44(4):551–562.
    1. Øiestad B.E., Juhl C.B., Eitzen I., Thorlund J.B. Knee extensor muscle weakness is a risk factor for development of knee osteoarthritis. A systematic review and meta-analysis. Osteoarthr Cartil. 2015;23(2):171–177.
    1. Risberg M.A., Grindem H., Oiestad B.E. We need to implement current evidence in early rehabilitation programs to improve long-term outcome after anterior cruciate ligament injury. J Orthop Sports Phys Ther. 2016;46(9):710–713.
    1. Toomey C.M., Whittaker J.L., Nettel-Aguirre A., Reimer R.A., Woodhouse L.J., Ghali B. Higher fat mass is associated with a history of knee injury in youth sport. J Orthop Sports Phys Ther. 2017;47(2):80–87.
    1. Bieler T., Sobol N.A., Andersen L.L., Kiel P., Lofholm P., Aagaard P. The effects of high-intensity versus low-intensity resistance training on leg extensor power and recovery of knee function after ACL-reconstruction. Biomed Res Int. 2014;2014:278512.
    1. Filbay S.R., Ackerman I.N., Dhupelia S., Arden N.K., Crossley K.M. Quality of life in symptomatic individuals after anterior cruciate ligament reconstruction, with and without radiographic knee osteoarthritis. J Orthop Sports Phys Ther. 2018;48(5):398–408.
    1. Chalmers P.N., Mall N.A., Moric M., Sherman S.L., Paletta G.P., Cole B.J. Does ACL reconstruction alter natural history? A systematic literature review of long-term outcomes. J Bone Joint Surg Am. 2014;96A(4):292–300.
    1. Smith T.O., Postle K., Penny F., McNamara I., Mann C.J.V. Is reconstruction the best management strategy for anterior cruciate ligament rupture? A systematic review and meta-analysis comparing anterior cruciate ligament reconstruction versus non-operative treatment. Knee. 2014;21(2):462–470.
    1. Delincé P., Ghafil D. Anterior cruciate ligament tears: conservative or surgical treatment? A critical review of the literature. Knee Surg Sports Traumatol Arthrosc. 2012;20(1):48–61.
    1. Harris K.P., Driban J.B., Sitler M.R., Cattano N.M., Balasubramanian E., Hootman J.M. Tibiofemoral osteoarthritis after surgical or nonsurgical treatment of anterior cruciate ligament rupture: a systematic review. J Athl Train. 2015 Jun;52(6):507–517. Epub 2015 Jun 26.
    1. Muaidi Q.I., Nicholson L.L., Refshauge K.M., Herbert R.D., Maher C.G. Prognosis of conservatively managed anterior cruciate ligament injury: a systematic review. Sports Med. 2007;37(8):703–716.
    1. Kay J., Memon M., Sa D., Simunovic N., Musahl V., Fu F.H. A historical analysis of randomized controlled trials in anterior cruciate ligament surgery. J Bone Joint Surg Am. 2017;99(24):2062–2068.
    1. Frobell R.B., Roos E.M., Roos H.P., Ranstam J., Lohmander L.S. A randomized trial of treatment for acute anterior cruciate ligament tears. N Engl J Med. 2010;363(4):331–342.
    1. Frobell R.B., Roos H.P., Roos E.M., Roemer F.W., Ranstam J., Lohmander L.S. Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial. BMJ. 2013;346(jan 24 1):f232.
    1. Wellsandt E., Failla M.J., Axe M.J., Snyder-Mackler L. Does anterior cruciate ligament reconstruction improve functional and radiographic outcomes over nonoperative management 5 Years after injury? Am J Sports Med. 2018 Jul;46(9):2103–2112. Epub 2018 Jun 21.
    1. Kovalak E., Atay T., Çetin C., Atay İ.M., Serbest M.O. Is ACL reconstruction a prerequisite for the patients having recreational sporting activities? Acta Orthop Traumatol Turc. 2018;52(1):37–43.
    1. van Yperen D.T., Reijman M., van Es E.M., Bierma-Zeinstra S.M.A., Meuffels D.E. Twenty-year follow-up study comparing operative versus nonoperative treatment of anterior cruciate ligament ruptures in high-level athletes. Am J Sports Med. 2018;46(5):1129–1136.
    1. Johnson D.H., Maffulli N., King J.B., Shelbourne K.D. Anterior cruciate ligament reconstruction: a cynical view from the British Isles on the indications for surgery. Arthroscopy. 2003;19(2):203.
    1. Grindem H., Eitzen I., Moksnes H., Snyder-Mackler L., Risberg M.A. A Pair-matched comparison of return to pivoting sports at 1 year in anterior cruciate ligament-injured patients after a nonoperative versus an operative treatment course. Am J Sports Med. 2012;40(11):2509–2516.
    1. Gerhard P., Bolt R., Dück K., Mayer R., Friederich N.F., Hirschmann M.T. Long-term results of arthroscopically assisted anatomical single-bundle anterior cruciate ligament reconstruction using patellar tendon autograft: are there any predictors for the development of osteoarthritis? Knee Surg Sports Traumatol Arthrosc. 2012:1–8.
    1. Røtterud J.H., Risberg M.A., Engebretsen L., Årøen A. Patients with focal full-thickness cartilage lesions benefit less from ACL reconstruction at 2-5 years follow-up. Knee Surg Sports Traumatol Arthrosc. 2012;20(8):1533–1539.
    1. van Meer B.L., Meuffels D.E., van Eijsden W.A., Verhaar J.A., Bierma-Zeinstra S.M., Reijman M. Which determinants predict tibiofemoral and patellofemoral osteoarthritis after anterior cruciate ligament injury? A systematic review. Br J Sports Med. 2015 Aug;49(15):975–983. Epub 2015 Mar 30.
    1. Claes S., Hermie L., Verdonk R., Bellemans J., Verdonk P. Is osteoarthritis an inevitable consequence of anterior cruciate ligament reconstruction? A meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2013;21(9):1967–1976.
    1. Magnussen R.A., Mansour A.A., Carey J.L., Spindler K.P. Meniscus status at anterior cruciate ligament reconstruction associated with radiographic signs of osteoarthritis at 5- to 10-year follow-up: a systematic review. J Knee Surg. 2009;22(4):347–357.
    1. Murray J.R.D., Lindh A.M., Hogan N.A., Trezies A.J., Hutchinson J.W., Parish E. Does anterior cruciate ligament reconstruction lead to degenerative disease?: thirteen-year results after bone–patellar tendon–bone autograft. Am J Sports Med. 2012;40(2):404–413.
    1. Keays S.L. Factors involved in the development of osteoarthritis after anterior cruciate ligament surgery. Am J Sports Med. 2010;38(3):455–463.
    1. Røtterud J.H., Sivertsen E.A., Forssblad M., Engebretsen L., Aroen A. Effect of meniscal and focal cartilage lesions on patient-reported outcome after anterior cruciate ligament reconstruction: a nationwide cohort study from Norway and Sweden of 8476 patients with 2-year follow-up. Am J Sports Med. 2013;41(3):535–543.
    1. Webster K.E., Feller J.A., Kimp A.J., Whitehead T.S. Revision anterior cruciate ligament reconstruction outcomes in younger patients: medial meniscal pathology and high rates of return to sport are associated with third ACL injuries. Am J Sports Med. 2018;46(5):1137–1142.
    1. Wright R.W., Huston L.J., Spindler K.P., Dunn W.R., Haas A.K., Allen C.R. Descriptive epidemiology of the multicenter ACL revision study (MARS) cohort. Am J Sports Med. 2010;38(10):1979–1986.
    1. Kievit A.J., Jonkers F.J., Barentsz J.H., Blankevoort L. A cross-sectional study comparing the rates of osteoarthritis, laxity, and quality of life in primary and revision anterior cruciate ligament reconstructions. Arthroscopy. 2013;29(5):898–905.
    1. Filbay S.R. Early ACL reconstruction is required to prevent additional knee injury: a misconception not supported by high-quality evidence. Br J Sports Med. 2018
    1. Grindem H., Eitzen I., Engebretsen L., Snyder-Mackler L., Risberg M.A. Nonsurgical or surgical treatment of ACL injuries: knee function, sports participation, and knee reinjury: the Delaware-Oslo ACL cohort study. J Bone Joint Surg Am. 2014;96(15):1233–1241.
    1. Wiggins A.J., Grandhi R.K., Schneider D.K., Stanfield D., Webster K.E., Myer G.D. Risk of secondary injury in younger athletes after anterior cruciate ligament reconstruction: a systematic review and meta-analysis. Am J Sports Med. 2016;44(7):1861–1876.
    1. Jones M.H., Spindler K.P. Risk factors for radiographic joint space narrowing and patient reported outcomes of post-traumatic osteoarthritis after ACL reconstruction: data from the MOON cohort. J Orthop Res. 2017;35(7):1366–1374.
    1. Filbay S.R., Roos E.M., Frobell R.B., Roemer F., Ranstam J., Lohmander L.S. Delaying ACL reconstruction and treating with exercise therapy alone may alter prognostic factors for 5-year outcome: an exploratory analysis of the KANON trial. Br J Sports Med. 2017:1–9.
    1. Hamrin Senorski E., Alentorn-Geli E., Musahl V., Fu F., Krupic F., Desai N. Increased odds of patient-reported success at 2 years after anterior cruciate ligament reconstruction in patients without cartilage lesions: a cohort study from the Swedish National Knee Ligament Register. Knee Surg Sports Traumatol Arthrosc. 2018;26(4):1086–1095.
    1. de Valk E.J., Moen M.H., Winters M., Bakker E.W., Tamminga R., van der Hoeven H. Preoperative patient and injury factors of successful rehabilitation after anterior cruciate ligament reconstruction with single-bundle techniques. Arthroscopy. 2013;29(11):1879–1895.
    1. Swirtun L.R., Renström P. Factors affecting outcome after anterior cruciate ligament injury: a prospective study with a six-year follow-up. Scand J Med Sci Sports. 2008;18(3):318–324.
    1. Thomeé P., Währborg P., Börjesson M., Thomeé R., Eriksson B., Karlsson J. Self-efficacy of knee function as a pre-operative predictor of outcome 1 year after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2008;16(2):118–127.
    1. Failla M.J., Logerstedt D.S., Grindem H., Axe M.J., Risberg M.A., Engebretsen L. Does extended preoperative rehabilitation influence outcomes 2 Years after ACL reconstruction? A comparative effectiveness study between the MOON and Delaware-Oslo ACL cohorts. Am J Sports Med. 2016;44(10):2608–2614.
    1. Grindem H., Granan L.P., Risberg M.A., Engebretsen L., Snyder-Mackler L., Eitzen I. How does a combined preoperative and postoperative rehabilitation programme influence the outcome of ACL reconstruction 2 years after surgery? A comparison between patients in the Delaware-Oslo ACL Cohort and the Norwegian National Knee Ligament Registry. Br J Sports Med. 2015;49(6):385–389.
    1. Shaarani S.R., O'Hare C., Quinn A., Moyna N., Moran R., O'Byrne J.M. Effect of prehabilitation on the outcome of anterior cruciate ligament reconstruction. Am J Sports Med. 2013;41(9):2117–2127.
    1. Grindem H., Wellsandt E., Failla M., Snyder-Mackler L., Risberg M.A. Anterior cruciate ligament injury-who succeeds without reconstructive surgery? The Delaware-Oslo ACL cohort study. Orthop J Sports Med. 2018;6(5) 2325967118774255.
    1. Feucht M.J., Cotic M., Saier T., Minzlaff P., Plath J.E., Imhoff A.B. Patient expectations of primary and revision anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2014 Jan;24(1):201–207. Epub 2014 Oct 2.
    1. Lohmander L.S., Östenberg A., Englund M., Roos H. High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury. Arthritis Rheum. 2004;50(10):3145–3152.
    1. Hall D.E., Prochazka A.V., Fink A.S. Informed consent for clinical treatment. CMAJ. 2012;184(5):533–540.
    1. Beaufils P., Hulet C., Dhenain M., Nizard R., Nourissat G., Pujol N. Clinical practice guidelines for the management of meniscal lesions and isolated lesions of the anterior cruciate ligament of the knee in adults. Orthop Traumatol Surg Res. 2009;95(6):437–442.
    1. Van Melick N., Van Cingel R.E.H., Brooijmans F., Neeter C., Van Tienen T., Hullegie W. Evidence-based clinical practice update: practice guidelines for anterior cruciate ligament rehabilitation based on a systematic review and multidisciplinary consensus. Br J Sports Med. 2016;50(24):1506–1515.
    1. Eitzen I., Moksnes H., Snyder-Mackler L., Risberg M.A. A progressive 5-week exercise therapy program leads to significant improvement in knee function early after anterior cruciate ligament injury. J Orthop Sports Phys Ther. 2010;40(11):705–721.
    1. Kim K.M., Croy T., Hertel J., Saliba S. Effects of neuromuscular electrical stimulation after anterior cruciate ligament reconstruction on quadriceps strength, function, and patient-oriented outcomes: a systematic review. J Orthop Sports Phys Ther. 2010;40(7):383–391.
    1. Blanchard S., Glasgow P. A theoretical model to describe progressions and regressions for exercise rehabilitation. Phys Ther Sport. 2014;15(3):131–135.
    1. Blanch P., Gabbett T.J. Has the athlete trained enough to return to play safely? The acute:chronic workload ratio permits clinicians to quantify a player's risk of subsequent injury. Br J Sports Med. 2016;50(8):471–475.
    1. Adams D., Logerstedt D.S., Hunter-Giordano A., Axe M.J., Snyder-Mackler L. Current concepts for anterior cruciate ligament reconstruction: a criterion-based rehabilitation progression. J Orthop Sports Phys Ther. 2012 Jul;42(7):601–614. 10.2519/jospt.2012.3871.
    1. Keays S.L., Bullock-Saxton J.E., Keays A.C., Newcombe P.A., Bullock M.I. A 6-year follow-up of the effect of graft site on strength, stability, range of motion, function, and joint degeneration after anterior cruciate ligament reconstruction: patellar tendon versus semitendinosus and Gracilis tendon graft. Am J Sports Med. 2007;35(5):729–739.
    1. Pinczewski L.A., Lyman J., Salmon L.J., Russell V.J., Roe J., Linklater J. A 10-year comparison of anterior cruciate ligament reconstructions with hamstring tendon and patellar tendon autograft: a controlled, prospective trial. Am J Sports Med. 2007;35(4):564–574.
    1. Suydam S.M., Cortes D.H., Axe M.J., Snyder-Mackler L., Buchanan T.S. Semitendinosus tendon for ACL reconstruction: regrowth and mechanical property recovery. Orthop J Sports Med. 2017;5(6) 2325967117712944.
    1. Ardern C.L., Webster K.E. Knee flexor strength recovery following hamstring tendon harvest for anterior cruciate ligament reconstruction: a systematic review. Orthop Rev (Pavia) 2009;1(2):e12.
    1. Ardern C.L., Glasgow P., Schneiders A., Witvrouw E., Clarsen B., Cools A. 2016 consensus statement on return to sport from the first world congress in sports physical therapy, bern. Br J Sports Med. 2016;50(14):853–864.
    1. Barber-Westin S.D., Noyes F.R. Factors used to determine return to unrestricted sports activities after anterior cruciate ligament reconstruction. Arthroscopy. 2011;27(12):1697–1705.
    1. Ardern C.L., Taylor N.F., Feller J.A., Whitehead T.S., Webster K.E. Psychological responses matter in returning to preinjury level of sport after anterior cruciate ligament reconstruction surgery. Am J Sports Med. 2013;41(7):1549–1558.
    1. Podlog L., Dimmock J., Miller J. A review of return to sport concerns following injury rehabilitation: practitioner strategies for enhancing recovery outcomes. Phys Ther Sport. 2011;12(1):36–42.
    1. Webster K.E., Feller J.A., Lambros C. Development and preliminary validation of a scale to measure the psychological impact of returning to sport following anterior cruciate ligament reconstruction surgery. Phys Ther Sport. 2008;9(1):9–15.
    1. Claes S., Verdonk P., Forsyth R., Bellemans J. The "ligamentization" process in anterior cruciate ligament reconstruction: what happens to the human graft? A systematic review of the literature. Am J Sports Med. 2011;39(11):2476–2483.
    1. Van Ginckel A., Verdonk P., Victor J., Witvrouw E. Cartilage status in relation to return to sports after anterior cruciate ligament reconstruction. Am J Sports Med. 2013;41(3):550–559.
    1. Laboute E., Savalli L., Puig P., Trouve P., Sabot G., Monnier G. Analysis of return to competition and repeat rupture for 298 anterior cruciate ligament reconstructions with patellar or hamstring tendon autograft in sportspeople. Ann Phys Rehabil Med. 2010;53(10):598–614.

Source: PubMed

3
S'abonner