GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann, GRADE Working Group, Phil Alderson, Pablo Alonso-Coello, Jeff Andrews, David Atkins, Hilda Bastian, Hans de Beer, Jan Brozek, Francoise Cluzeau, Jonathan Craig, Ben Djulbegovic, Yngve Falck-Ytter, Beatrice Fervers, Signe Flottorp, Paul Glasziou, Gordon Guyatt, Robin Harbour, Margaret Haugh, Mark Helfand, Mark Helfand, Roman Jaeschke, Kathatrine Jones, Ilkka Kunnamo, Regina Kunz, Alessandro Liberati, Merce Marzo, James Mason, Jacek Mrukovics, Susan Norris, Andrew Oxman, Vivian Robinson, Holger Schünemann, Tessa Tan Torres, David Tovey, Peter Tugwell, Mariska Tuut, Helena Varonen, Gunn Vist, Craig Wittington, John Williams, James Woodcock, Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann, GRADE Working Group, Phil Alderson, Pablo Alonso-Coello, Jeff Andrews, David Atkins, Hilda Bastian, Hans de Beer, Jan Brozek, Francoise Cluzeau, Jonathan Craig, Ben Djulbegovic, Yngve Falck-Ytter, Beatrice Fervers, Signe Flottorp, Paul Glasziou, Gordon Guyatt, Robin Harbour, Margaret Haugh, Mark Helfand, Mark Helfand, Roman Jaeschke, Kathatrine Jones, Ilkka Kunnamo, Regina Kunz, Alessandro Liberati, Merce Marzo, James Mason, Jacek Mrukovics, Susan Norris, Andrew Oxman, Vivian Robinson, Holger Schünemann, Tessa Tan Torres, David Tovey, Peter Tugwell, Mariska Tuut, Helena Varonen, Gunn Vist, Craig Wittington, John Williams, James Woodcock
Abstract
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwide
Conflict of interest statement
Competing interests: All authors are involved in the dissemination of GRADE, and GRADE’s success has a positive influence on their academic career. Authors listed in the byline have received travel reimbursement and honorariums for presentations that included a review of GRADE’s approach to rating quality of evidence and grading recommendations. GHG acts as a consultant to UpToDate; his work includes helping UpToDate in their use of GRADE. HJS is documents editor and methodologist for the American Thoracic Society; one of his roles in these positions is helping implement the use of GRADE. He is supported by “The human factor, mobility and Marie Curie actions scientist reintegration European Commission grant: IGR 42192—GRADE.”
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Source: PubMed