Apps and Adolescents: A Systematic Review of Adolescents' Use of Mobile Phone and Tablet Apps That Support Personal Management of Their Chronic or Long-Term Physical Conditions

Rabiya Majeed-Ariss, Eileen Baildam, Malcolm Campbell, Alice Chieng, Debbie Fallon, Andrew Hall, Janet E McDonagh, Simon R Stones, Wendy Thomson, Veronica Swallow, Rabiya Majeed-Ariss, Eileen Baildam, Malcolm Campbell, Alice Chieng, Debbie Fallon, Andrew Hall, Janet E McDonagh, Simon R Stones, Wendy Thomson, Veronica Swallow

Abstract

Background: The prevalence of physical chronic or long-term conditions in adolescents aged 10-24 years is rising. Mobile phone and tablet mobile technologies featuring software program apps are widely used by these adolescents and their healthy peers for social networking or gaming. Apps are also used in health care to support personal condition management and they have considerable potential in this context. There is a growing body of literature on app use in health contexts, thereby making a systematic review of their effectiveness very timely.

Objective: To systematically review the literature on the effectiveness of mobile apps designed to support adolescents' management of their physical chronic or long-term conditions.

Methods: We conducted a review of the English-language literature published since 2003 in five relevant bibliographical databases using key search terms. Two independent reviewers screened titles and abstracts using data extraction and quality assessment tools.

Results: The search returned 1120 hits. Of the 19 eligible full-text papers, four met our review criteria, reporting one pilot randomized controlled trial and three pretest/post-test studies. Samples ranged from 4 to 18 participants, with a combined sample of 46 participants. The apps reported were targeted at type 1 diabetes, asthma, and cancer. Two papers provided data for calculating effect size. Heterogeneity in terms of study design, reported outcomes, follow-up times, participants' ages, and health conditions prevented meta-analyses. There was variation in whether adolescents received guidance in using the app or were solely responsible for navigating the app. Three studies reported some level of patient involvement in app design, development, and/or evaluation. Health professional involvement in the modelling stages of apps was reported in all studies, although it was not always clear whether specific clinical (as opposed to academic) expertise in working with adolescents was represented. The dearth of studies and the small overall sample size emphasizes the need for future studies of the development, evaluation, use, and effectiveness of mobile apps to support adolescents' personal management of their conditions.

Conclusions: A key finding of the review is the paucity of evidence-based apps that exist, in contrast to the thousands of apps available on the app market that are not evidence-based or user or professional informed. Although we aimed to assess the effectiveness of apps, the dearth of studies meeting our criteria meant that we were unable to be conclusive in this regard. Based on the available evidence, apps may be considered feasible health interventions, but more studies involving larger sample sizes, and with patient and health professional input at all stages, are needed to determine apps' acceptability and effectiveness. This review provides valuable findings and paves the way for future rigorous development and evaluation of health apps for adolescents with chronic or long-term conditions.

Keywords: adolescents; arthritis; asthma; cancer; chronic disease or condition; diabetes; long-term condition; mobile or tablet apps; personal or self-management; review; young people.

Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
PRISMA flow diagram of the review.

References

    1. Jackson Allen P. The primary care provider and children with chronic conditions. In: Jackson Allen P, Vessey JA, Schapiro N, editors. Primary Care of the Child with a Chronic Condition. 5th edition. St. Louis, MO: Mosby; 2010. pp. 3–21.
    1. Brooks F, Magnusson J, Klemera E, Spencer N, Morgan A. Health Behaviour in School-aged Children (HBSC): World Health Organization Collaborative Cross National Study. Hatfield, UK: University of Hertfordshire; 2011. Oct, [2015-12-03]. .
    1. Swallow V. Special issue on children, young people, and families living with long-term conditions. J Pediatr Nurs. 2015;30(1):1–3. doi: 10.1016/j.pedn.2014.10.015.
    1. Sawyer SM, Afifi RA, Bearinger LH, Blakemore S, Dick B, Ezeh AC, Patton GC. Adolescence: A foundation for future health. Lancet. 2012 Apr 28;379(9826):1630–1640. doi: 10.1016/S0140-6736(12)60072-5.
    1. Colver A, Longwell S. New understanding of adolescent brain development: Relevance to transitional healthcare for young people with long term conditions. Arch Dis Child. 2013 Nov;98(11):902–907. doi: 10.1136/archdischild-2013-303945.
    1. Ambresin A, Bennett K, Patton GC, Sanci LA, Sawyer SM. Assessment of youth-friendly health care: A systematic review of indicators drawn from young people's perspectives. J Adolesc Health. 2013 Jun;52(6):670–681. doi: 10.1016/j.jadohealth.2012.12.014.
    1. Crowley R, Wolfe I, Lock K, McKee M. Improving the transition between paediatric and adult healthcare: A systematic review. Arch Dis Child. 2011 Jun;96(6):548–553. doi: 10.1136/adc.2010.202473.
    1. McDonagh J. Has the gap been bridged yet? Young people in paediatric and adult rheumatology. Rheumatology (Oxford) 2013 Aug;52(8):1349–1351. doi: 10.1093/rheumatology/kes407.
    1. Stinson J, Kohut SA, Spiegel L, White M, Gill N, Colbourne G, Sigurdson S, Duffy KW, Tucker L, Stringer E, Hazel B, Hochman J, Reiss J, Kaufman M. A systematic review of transition readiness and transfer satisfaction measures for adolescents with chronic illness. Int J Adolesc Med Health. 2014;26(2):159–174. doi: 10.1515/ijamh-2013-0512.
    1. Department of Health . Improving Children and Young People’s Health Outcomes: A System Wide Response. London, UK: Department of Health; 2013. Feb, [2015-12-03]. .
    1. Dennison L, Morrison L, Conway G, Yardley L. Opportunities and challenges for smartphone applications in supporting health behavior change: Qualitative study. J Med Internet Res. 2013;15(4):e86. doi: 10.2196/jmir.2583.
    1. Free C, Phillips G, Galli L, Watson L, Felix L, Edwards P, Patel V, Haines A. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: A systematic review. PLoS Med. 2013;10(1):e1001362. doi: 10.1371/journal.pmed.1001362.
    1. Gray NJ, McDonagh JE, Harvey K, Prescott J, Roberts R, Shaw KL, Smith FJ, Stephenson R, Terry D, Fleck K. Arthriting: Exploring the Relationship Between Identity and Medicines Use, and to Identify the Contribution of Medicines and Pharmacy Services, for the Care of Young People With Arthritis. London, UK: Pharmacy Research UK; 2013. Dec, [2015-12-04]. .
    1. Pai ALH, Ostendorf HM. Treatment adherence in adolescents and young adults affected by chronic illness during the health care transition from pediatric to adult health care: A literature review. Child Health Care. 2011;40(1):16–33. doi: 10.1080/02739615.2011.537934.
    1. Dean AJ, Walters J, Hall A. A systematic review of interventions to enhance medication adherence in children and adolescents with chronic illness. Arch Dis Child. 2010 Sep;95(9):717–723. doi: 10.1136/adc.2009.175125.
    1. Pai ALH, McGrady M. Systematic review and meta-analysis of psychological interventions to promote treatment adherence in children, adolescents, and young adults with chronic illness. J Pediatr Psychol. 2014 Sep;39(8):918–931. doi: 10.1093/jpepsy/jsu038.
    1. Wu YP, Hommel KA. Using technology to assess and promote adherence to medical regimens in pediatric chronic illness. J Pediatr. 2014 Apr;164(4):922–927. doi: 10.1016/j.jpeds.2013.11.013.
    1. Lorig KR, Holman H. Self-management education: History, definition, outcomes, and mechanisms. Ann Behav Med. 2003 Aug;26(1):1–7.
    1. The Communications Market Report. London, UK: Ofcom; 2014. Aug 07, [2015-11-27]. .
    1. Wang J, Wang Y, Wei C, Yao NA, Yuan A, Shan Y, Yuan C. Smartphone interventions for long-term health management of chronic diseases: An integrative review. Telemed J E Health. 2014 Jun;20(6):570–583. doi: 10.1089/tmj.2013.0243.
    1. Obiodu V, Obiodu E. An empirical review of the top 500 medical apps in a European Android market. J Mob Technol Med. 2012 Dec 22;1(4):22–37. doi: 10.7309/jmtm.74.
    1. Transforming Participation in Health and Care: ‘The NHS belongs to us all’. London, UK: Patients and Information Directorate, NHS England; 2013. [2015-12-04]. .
    1. Aitken M, Gauntlett C. Patient Apps for Improved Healthcare: From Novelty to Mainstream. Parsippany, NJ: IMS Institute for Healthcare Informatics; 2013. Oct, [2015-12-04]. .
    1. Misra S, Lewis TL, Aungst TD. Medical application use and the need for further research and assessment for clinical practice: Creation and integration of standards for best practice to alleviate poor application design. JAMA Dermatol. 2013 Jun;149(6):661–662. doi: 10.1001/jamadermatol.2013.606.
    1. Department of Child and Adolescent Health and Development . The Second Decade: Improving Adolescent Health and Development. Geneva, Switzerland: World Health Organization; 2001. [2015-12-04]. .
    1. UNESCO. [2015-11-27]. What do we mean by “youth”?
    1. Majeed-Ariss R, Hall AG, McDonagh J, Fallon D, Swallow V. Mobile phone and tablet apps to support young people's management of their physical long-term conditions: A systematic review protocol. JMIR Res Protoc. 2015 Apr 07;4(2):e40. doi: 10.2196/resprot.4159.
    1. Green S, Higgins JPT. Cochrane Handbook for Systematic Reviews of Interventions. Chichester, UK: John Wiley & Sons; 2008. Nov, [2015-12-04]. Preparing a Cochrane review .
    1. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration. BMJ. 2009 Jul 21;339:b2700.
    1. Majeed-Ariss R, Hall A, Fallon D, McDonagh J, Swallow V. PROSPERO. York, UK: University of York; 2014. [2015-03-31]. Smartphone and tablet apps for children and young people’s management of physical long-term conditions: A systematic review .
    1. BBC News. 2003. Mar 03, [2015-12-04]. 3G goes live in the UK .
    1. TMCnet. 2007. Mar 19, [2015-12-06]. GSA announces 100 commercial HSDPA networks worldwide .
    1. Systematic Reviews: CRD’s Guidance for Undertaking Reviews in Health Care. York, UK: Centre for Reviews and Dissemination, University of York; 2009. Jan, [2015-12-04]. .
    1. Quality Assessment Tool for Quantitative Studies. Hamilton, ON: Effective Public Health Practice Project; 2010. [2015-12-04]. .
    1. Armijo-Olivo S, Stiles CR, Hagen NA, Biondo PD, Cummings GG. Assessment of study quality for systematic reviews: A comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: Methodological research. J Eval Clin Pract. 2012 Feb;18(1):12–18. doi: 10.1111/j.1365-2753.2010.01516.x.
    1. Altman DG. Practical Statistics for Medical Research. London, UK: Chapman & Hall/CRC; 1990.
    1. VassarStats. [2015-11-26].
    1. Fleiss JL, Cohen J. Educ Psychol Meas. 1973. [2015-12-04]. The equivalence of weighted kappa and the intraclass correlation coefficient as measures of reliability .
    1. Burbank A, Lewis SD, Hewes M, Schellhase DE, Rettiganti M, Hall-Barrow J, Bylander LA, Brown RH, Perry TT. Mobile-based asthma action plans for adolescents. J Asthma. 2015;52(6):583–586. doi: 10.3109/02770903.2014.995307.
    1. Ryan D, Price D, Musgrave SD, Malhotra S, Lee AJ, Ayansina D, Sheikh A, Tarassenko L, Pagliari C, Pinnock H. Clinical and cost effectiveness of mobile phone supported self monitoring of asthma: Multicentre randomised controlled trial. BMJ. 2012;344:e1756.
    1. Stinson JN, Lalloo C, Harris L, Isaac L, Campbell F, Brown S, Ruskin D, Gordon A, Galonski M, Pink LR, Buckley N, Henry JL, White M, Karim A. iCanCope with Pain™: User-centred design of a Web- and mobile-based self-management program for youth with chronic pain based on identified health care needs. Pain Res Manag. 2014;19(5):257–265.
    1. Kumar N, Khan RA, Kumar P, Sharma VP. E-health: Stipulation of mobile phone technology in adolescent diabetic patient care in pediatric diabetes. Proceedings of the the Annual Conference of the International Society for Pediatric and Adolescent Diabetes; Annual Conference of the International Society for Pediatric and Adolescent Diabetes; October 10-13, 2012; Istanbul, Turkey. 2012.
    1. Scaramuzza A, Bosetti A, Redaelli F, Gazzarri A, Rossi E, Ferrari M, Zuccotti GV. To WhatsApp or not to WhatsApp? What could be done with new social media to manage type 1 diabetes in adolescents. Proceedings of the 7th International Conference on Advanced Technologies & Treatments for Diabetes; 7th International Conference on Advanced Technologies & Treatments for Diabetes; February 5-8, 2014; Vienna, Austria. 2014.
    1. Kovatchev BP. Clinical results from transitional and home trials of outpatient closed-loop control. Proceedings of the 7th International Conference on Advanced Technologies & Treatments for Diabetes; 7th International Conference on Advanced Technologies & Treatments for Diabetes; February 5-8, 2014; Vienna, Austria. 2014.
    1. Stukus D, Phillips G, Farooqui N. Improved education and self-management in children and adolescents with asthma using a personalized smartphone application. Proceedings of the Annual Meeting of the American Academy of Allergy, Asthma and Immunology; Annual Meeting of the American Academy of Allergy, Asthma and Immunology; February 28-March 4, 2014; San Diego, CA. 2014.
    1. Cummings E, Hauser J, Cameron-Tucker H, Fitzpatrick P, Jessup M, Walters EH, Reid D, Turner P. Enhancing self-efficacy for self-management in people with cystic fibrosis. Stud Health Technol Inform. 2011;169:33–37.
    1. Jacob E, Stinson J, Duran J, Gupta A, Gerla M, Ann LM, Zeltzer L. Usability testing of a smartphone for accessing a Web-based e-diary for self-monitoring of pain and symptoms in sickle cell disease. J Pediatr Hematol Oncol. 2012 Jul;34(5):326–335. doi: 10.1097/MPH.0b013e318257a13c.
    1. Leone JR. Utility of a wireless, handheld monitoring system in the management of hemophilia patients. Comput Inform Nurs. 2011 Sep;29(9):521–522. doi: 10.1097/NCN.0b013e3182066356.
    1. Carroll AE, DiMeglio LA, Stein S, Marrero DG. Contracting and monitoring relationships for adolescents with type 1 diabetes: A pilot study. Diabetes Technol Ther. 2011 May;13(5):543–549. doi: 10.1089/dia.2010.0181.
    1. Jessup M, Hauser J, Cameron-Tucker H, Cummings E, Turner P, Blizzard L, Reid D. Facilitating self-management in adolescents and adults with cystic fibrosis: A pilot study. Pediatr Pulmonol. 2011;46(Suppl 34):405.
    1. Marciel KK, Saiman L, Quittell LM, Dawkins K, Quittner AL. Cell phone intervention to improve adherence: Cystic fibrosis care team, patient, and parent perspectives. Pediatr Pulmonol. 2010 Feb;45(2):157–164. doi: 10.1002/ppul.21164.
    1. McClellan CB, Schatz JC, Puffer E, Sanchez CE, Stancil MT, Roberts CW. Use of handheld wireless technology for a home-based sickle cell pain management protocol. J Pediatr Psychol. 2009 Jun;34(5):564–573. doi: 10.1093/jpepsy/jsn121.
    1. McCann L, Maguire R, Miller M, Kearney N. Patients' perceptions and experiences of using a mobile phone-based advanced symptom management system (ASyMS) to monitor and manage chemotherapy related toxicity. Eur J Cancer Care (Engl) 2009 Mar;18(2):156–164. doi: 10.1111/j.1365-2354.2008.00938.x.
    1. Kumar VS, Wentzell KJ, Mikkelsen T, Pentland A, Laffel LM. The DAILY (Daily Automated Intensive Log for Youth) trial: A wireless, portable system to improve adherence and glycemic control in youth with diabetes. Diabetes Technol Ther. 2004 Aug;6(4):445–453. doi: 10.1089/1520915041705893.
    1. Cafazzo J, Casselman M, Hamming N, Katzman DK, Palmert MR. Design of an mHealth app for the self-management of adolescent type 1 diabetes: A pilot study. J Med Internet Res. 2012;14(3):e70. doi: 10.2196/jmir.2058.
    1. Frøisland DH, Arsand E, Skårderud F. Improving diabetes care for young people with type 1 diabetes through visual learning on mobile phones: Mixed-methods study. J Med Internet Res. 2012;14(4):e111. doi: 10.2196/jmir.2155.
    1. Aldiss S, Taylor RM, Soanes L, Maguire R, Sage M, Kearney N, Gibson F. Working in collaboration with young people and health professionals. A staged approach to the implementation of a randomised controlled trial. J Res Nurs. 2010 Sep 17;16(6):561–576. doi: 10.1177/1744987110380803.
    1. Varni JW, Burwinkle TM, Katz ER, Meeske K, Dickinson P. The PedsQL in pediatric cancer: Reliability and validity of the Pediatric Quality of Life Inventory Generic Core Scales, Multidimensional Fatigue Scale, and Cancer Module. Cancer. 2002 Apr 1;94(7):2090–2106.
    1. Enskär K, Carlsson M, Golsäter M, Hamrin E. Symptom distress and life situation in adolescents with cancer. Cancer Nurs. 1997 Feb;20(1):23–33.
    1. Spielberger CD, Gorsuch RL, Lushene R, Vagg PR, Jacobs GA. Manual for the State-Trait Anxiety Inventory. Palo Alto, CA: Consulting Psychologists Press; 1983.
    1. Gibson F, Aldiss S, Taylor RM, Maguire R, McCann L, Sage M, Kearney N. Utilization of the Medical Research Council evaluation framework in the development of technology for symptom management: The ASyMS-YG Study. Cancer Nurs. 2010;33(5):343–352. doi: 10.1097/NCC.0b013e3181cb4bad.
    1. Gibson F, Aldiss S, Taylor RM, Maguire R, Kearney N. Involving health professionals in the development of an advanced symptom management system for young people: The ASyMS-YG study. Eur J Oncol Nurs. 2009 Jul;13(3):187–192. doi: 10.1016/j.ejon.2009.03.004.
    1. Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd edition. Hillsdale, NJ: Erlbaum Associates; 1988.
    1. Donker T, Petrie K, Proudfoot J, Clarke J, Birch M, Christensen H. Smartphones for smarter delivery of mental health programs: A systematic review. J Med Internet Res. 2013;15(11):e247. doi: 10.2196/jmir.2791.
    1. Grissom RJ, Kim JJ. Effect Sizes for Research: A Broad Practical Approach. Mahwah, NJ: Erlbaum Associates; 2005.
    1. Daniel T, Kostic B. RStats Institute, Missouri State University. 2015. [2015-12-04]. RStats effect size calculator .
    1. Heron KE, Smyth JM. Ecological momentary interventions: Incorporating mobile technology into psychosocial and health behaviour treatments. Br J Health Psychol. 2010 Feb;15(Pt 1):1–39. doi: 10.1348/135910709X466063.
    1. Buijink AW, Visser BJ, Marshall L. Medical apps for smartphones: Lack of evidence undermines quality and safety. Evid Based Med. 2013 Jun;18(3):90–92. doi: 10.1136/eb-2012-100885.
    1. Craig C, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M, Medical Research Council Guidance Developing and evaluating complex interventions: The new Medical Research Council guidance. BMJ. 2008;337:a1655.
    1. Pai ALH, Ostendorf HM. Treatment adherence in adolescents and young adults affected by chronic illness during the health care transition from pediatric to adult health care: A literature review. Child Health Care. 2011 Jan;40(1):16–33. doi: 10.1080/02739615.2011.537934.
    1. Santer M, Ring N, Yardley L, Geraghty AW, Wyke S. Treatment non-adherence in pediatric long-term medical conditions: Systematic review and synthesis of qualitative studies of caregivers' views. BMC Pediatr. 2014;14:63. doi: 10.1186/1471-2431-14-63.
    1. Hood KK, Rohan JM, Peterson CM, Drotar D. Interventions with adherence-promoting components in pediatric type 1 diabetes: Meta-analysis of their impact on glycemic control. Diabetes Care. 2010 Jul;33(7):1658–1664. doi: 10.2337/dc09-2268.
    1. Heron KE, Smyth JM. Ecological momentary interventions: Incorporating mobile technology into psychosocial and health behaviour treatments. Br J Health Psychol. 2010 Feb;15(Pt 1):1–39. doi: 10.1348/135910709X466063.
    1. Suris J, Akré C, Berchtold A, Bélanger RE, Michaud P. Chronically connected? Internet use among adolescents with chronic conditions. J Adolesc Health. 2010 Feb;46(2):200–202. doi: 10.1016/j.jadohealth.2009.07.008.
    1. Suris JC, Akre C, Piguet C, Ambresin AE, Zimmermann G, Berchtold A. Is Internet use unhealthy? A cross-sectional study of adolescent Internet overuse. Swiss Med Wkly. 2014;144:w14061. doi: 10.4414/smw.2014.14061.
    1. INVOLVE. London, UK: NIHR; [2015-11-27]. What is public involvement in research?
    1. McDonagh JE, Bateman B. 'Nothing about us without us': Considerations for research involving young people. Arch Dis Child Educ Pract Ed. 2012 Apr;97(2):55–60. doi: 10.1136/adc.2010.197947.
    1. Nightingale R, Sinha MD, Swallow V. Using focused ethnography in paediatric settings to explore professionals' and parents' attitudes towards expertise in managing chronic kidney disease stage 3-5. BMC Health Serv Res. 2014;14:403. doi: 10.1186/1472-6963-14-403.
    1. Swallow V. An exploration of mothers' and fathers' views of their identities in chronic-kidney-disease management: Parents as students? J Clin Nurs. 2008 Dec;17(23):3177–3186. doi: 10.1111/j.1365-2702.2008.02642.x.
    1. Hardoff D, Danziger Y, Reisler G, Stoffman N, Ziv A. Minding the gap: Training in adolescent medicine when formal training programmes are not available. Arch Dis Child Educ Pract Ed. 2009 Oct;94(5):157–160. doi: 10.1136/adc.2008.155762.
    1. Swallow V, Clarke CL, Iles S, Harden J. Work based, lifelong learning through professional portfolios: Challenge or reward? Pharm Educ. 2006;6(2):77–89.
    1. Marr S, Steele K, Swallow V, Craggs S, Procter S, Newton J, Sen B, McNabb A. Mapping the range and scope of emergency nurse practitioner services in the Northern and Yorkshire Region: A telephone survey. Emerg Med J. 2003 Sep;20(5):414–417.
    1. Brown T. Are you a digital native or digital immigrant: Being client centred in the digital era. Br J Occup Ther. 2011 Jul;74(7):313.
    1. Farrer L, Gulliver A, Chan JK, Batterham PJ, Reynolds J, Calear A, Tait R, Bennett K, Griffiths KM. Technology-based interventions for mental health in tertiary students: Systematic review. J Med Internet Res. 2013;15(5):e101. doi: 10.2196/jmir.2639.
    1. Majeed-Ariss R, Fallon D, Hall A, McDonagh J, Swallow V. Health theory in mobile technology apps supporting young people's long-term condition/s management: A systematic review [in press] Bull Eur Health Psychol Soc. 2015 in press.

Source: PubMed

3
S'abonner