Correlation between semen analysis by motile sperm organelle morphology examination and sperm DNA damage

Joao Batista Alcantara Oliveira, Fabiana Cagnoto Massaro, Ricardo Luis Razera Baruffi, Ana Lúcia Mauri, Claudia Guilhermino Petersen, Liliane F I Silva, Laura D Vagnini, José Gonçalves Franco Jr, Joao Batista Alcantara Oliveira, Fabiana Cagnoto Massaro, Ricardo Luis Razera Baruffi, Ana Lúcia Mauri, Claudia Guilhermino Petersen, Liliane F I Silva, Laura D Vagnini, José Gonçalves Franco Jr

Abstract

Regression analysis of 538 semen samples demonstrated that percentages of normal nuclear sperm and all spermatozoa with abnormalities of nuclear form at high magnification had significant negative correlation with percentages of DNA fragmentation. On the other hand, there was a positive correlation between percentages of spermatozoa with nuclear vacuoles and those with DNA fragmentation.

Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Source: PubMed

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