Successful management of aluminium phosphide poisoning using intravenous lipid emulsion: Report of two cases

Udismita Baruah, Ameeta Sahni, Harish C Sachdeva, Udismita Baruah, Ameeta Sahni, Harish C Sachdeva

Abstract

Aluminum phosphide (ALP) is a cheap, easily available agricultural pesticide which causes lethal poisoning by liberation of phosphine and inhibition of cytochrome c oxidase thereby leading to cellular hypoxia. Although there is no known specific antidote, clinical trials are still going on. We present here two cases of ALP poisoning who were successfully managed by treatment with lipid emulsion and intravenous magnesium sulfate.

Keywords: Aluminum phosphide; lipid emulsions; magnesium sulfate.

Figures

Graph 1
Graph 1
Serum magnesium level (mg/ml) in first patient
Graph 2
Graph 2
Serum magnesium level (mg/ml) in second patient

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