The feasibility of implementing an exercise programme for deconditioned cancer survivors in a national cancer centre: FIXCAS Study

Kate Devenney, Niamh Murphy, Ronan Ryan, Clíona Grant, John Kennedy, Rustom P Manecksha, Orla Sheils, Margaret L McNeely, Juliette Hussey, Grainne Sheill, Kate Devenney, Niamh Murphy, Ronan Ryan, Clíona Grant, John Kennedy, Rustom P Manecksha, Orla Sheils, Margaret L McNeely, Juliette Hussey, Grainne Sheill

Abstract

Introduction: As both the number of cancer survivors and the length of survival time are increasing, long-term health issues related to cancer and its treatment are becoming more prevalent. Research suggests that exercise can mitigate several negative health consequences in cancer survivors and improve physical function and quality of life. Multi-modal exercise interventions have been proposed as a cornerstone for survivorship care. However, studies evaluating exercise programmes within the Irish population are lacking. Purpose: To evaluate the introduction, implementation and acceptability of a multi-modal exercise rehabilitation programme for deconditioned cancer survivors in a real-world, standard practice setting. Methods and analysis: In this single-arm prospective feasibility study, cancer survivors (n=40) will undergo a 10-week multi-modal exercise programme. The study population will comprise of cancer survivors attending outpatient services in an Irish national cancer centre. Participants will be aged 18 or older and have completed treatment with curative intent. Feasibility will be evaluated in terms of recruitment, adherence and compliance to the programme. Secondary outcomes will examine physical function and quality of life measures. In addition, the acceptability of the programme will be assessed through stakeholder feedback. Ethics and dissemination: Ethical approval through the St. James's Hospital and Tallaght University Hospital Research and Ethics Committee is currently pending. The study results will be used to optimise the intervention content and may serve as the foundation for a larger definitive trial. Results will be disseminated through peer-review journals, congresses and relevant clinical groups. Trial registration: ClinicalTrials.gov NCT04026659 (19/07/19).

Keywords: Cancer; Exercise; Rehabilitation.

Conflict of interest statement

No competing interests were disclosed.

Copyright: © 2020 Devenney K et al.

References

    1. Dis Esophagus. 2017 Aug 1;30(8):1-7
    1. J Natl Cancer Inst Monogr. 2004;(32):57-71
    1. Int J Sports Med. 2013 Jul;34(7):631-6
    1. Ir Med J. 2018 Oct 11;111(9):818
    1. Urology. 1995 Nov;46(5):697-706
    1. Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7
    1. J Neurol. 2002 Jan;249(1):9-17
    1. Qual Life Res. 2011 Dec;20(10):1727-36
    1. Ann Surg. 2018 Nov;268(5):747-755
    1. Cancer Pract. 2001 May-Jun;9(3):119-27
    1. CMAJ. 2006 Jul 4;175(1):34-41
    1. Psychooncology. 2009 Dec;18(12):1273-80
    1. Support Care Cancer. 2012 Feb;20(2):221-33
    1. Br J Soc Psychol. 2003 Mar;42(Pt 1):129-46
    1. Cancer. 1999 Mar 1;85(5):1186-96
    1. Med Sci Sports Exerc. 2010 Jul;42(7):1409-26
    1. CA Cancer J Clin. 2016 Jul;66(4):271-89
    1. Lung Cancer. 2012 Feb;75(2):203-8
    1. Ann Oncol. 2008 Apr;19(4):623-9
    1. Ann Surg. 2005 Aug;242(2):212-23
    1. J Clin Oncol. 2005 Feb 1;23(4):899-909
    1. J Strength Cond Res. 2006 Feb;20(1):14-21
    1. J Clin Oncol. 2014 Aug 20;32(24):2662-8
    1. J Natl Cancer Inst. 1993 Mar 3;85(5):365-76
    1. Pain. 1999 Sep;82(3):263-274
    1. Urology. 2004 Jun;63(6):1076-8
    1. Ann Surg. 2017 Nov;266(5):822-830
    1. Cancer. 2007 Jun 15;109(12):2607-14
    1. Public Health Nutr. 2006 Sep;9(6):755-62
    1. Br J Soc Psychol. 2001 Dec;40(Pt 4):471-99
    1. Ann Behav Med. 1999 Spring;21(2):171-9
    1. Eur J Cancer Care (Engl). 2003 Dec;12(4):347-57
    1. J Cancer Surviv. 2013 Dec;7(4):551-62
    1. J Clin Oncol. 2006 Nov 10;24(32):5117-24

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