A Social Media Website (Supporting Our Valued Adolescents) to Support Treatment Uptake for Adolescents With Depression or Anxiety: Pilot Randomized Controlled Trial

Ana Radovic, Yaming Li, Doug Landsittel, Kayla R Odenthal, Bradley D Stein, Elizabeth Miller, Ana Radovic, Yaming Li, Doug Landsittel, Kayla R Odenthal, Bradley D Stein, Elizabeth Miller

Abstract

Background: Adolescents with depression or anxiety initiate mental health treatment in low numbers. Supporting Our Valued Adolescents (SOVA) is a peer support website intervention for adolescents seen in primary care settings and their parents with the goal of increasing treatment uptake through changing negative health beliefs, enhancing knowledge, offering peer emotional support, and increasing parent-adolescent communication about mental health.

Objective: This pilot study aimed to refine recruitment and retention strategies, refine document intervention fidelity, and explore changes in study outcomes (the primary outcome being treatment uptake).

Methods: We conducted a 2-group, single-blind, pilot randomized controlled trial in a single adolescent medicine clinic. Participants were aged 12 to 19 years with clinician-identified symptoms of depression or anxiety for which a health care provider recommended treatment. The patient and parent, if interested, were randomized to receive the SOVA websites and enhanced usual care (EUC) compared with EUC alone. Baseline, 6-week, and 3-month measures were collected using a web-based self-report survey and blinded electronic health record review. The main pilot outcomes assessed were the feasibility of recruitment and retention strategies. Implementation outcomes, intervention fidelity, missingness, and adequacy of safety protocols were documented. Descriptive statistics were used to summarize mental health service use and target measures with 2-sample t tests to compare differences between arms.

Results: Less than half of the adolescents who were offered patient education material (195/461, 42.2%) were referred by their clinician to the study. Of 146 adolescents meeting the inclusion criteria, 38 completed the baseline survey, qualifying them for randomization, and 25 (66%, 95% CI 51%-81%) completed the 6-week measures. There was limited engagement in the treatment arm, with 45% (5/11) of adolescents who completed 6-week measures reporting accessing SOVA, and most of those who did not access cited forgetting as the reason. Changes were found in target factors at 6 weeks but not in per-protocol analyses. At 12 weeks, 83% (15/18) of adolescents randomized to SOVA received mental health treatment as compared with 50% (10/20) of adolescents randomized to EUC (P=.03).

Conclusions: In this pilot trial of a peer support website intervention for adolescents with depression or anxiety, we found lower-than-expected study enrollment after recruitment. Although generalizability may be enhanced by not requiring parental permission for adolescent participation in the trials of mental health interventions, this may limit study recruitment and retention. We found that implementing education introducing the study into provider workflow was feasible and acceptable, resulting in almost 500 study referrals. Finally, although not the primary outcome, we found a signal for greater uptake of mental health treatment in the arm using the SOVA intervention than in the usual care arm.

Trial registration: ClinicalTrials.gov NCT03318666; https://ichgcp.net/clinical-trials-registry/NCT03318666.

International registered report identifier (irrid): RR2-10.2196/12117.

Keywords: adolescent; adolescent health services; anxiety; depression; technology.

Conflict of interest statement

Conflicts of Interest: EM receives royalties from Wolters Kluwer Inc for writing content for UpToDate not related to this work. AR serves on the scientific advisory board of Appa Health, which provided them with stock options. Their work and the work in this paper do not overlap and the author does not conduct research for them.

©Ana Radovic, Yaming Li, Doug Landsittel, Kayla R Odenthal, Bradley D Stein, Elizabeth Miller. Originally published in JMIR Mental Health (https://mental.jmir.org), 07.10.2022.

Figures

Figure 1
Figure 1
CONSORT (Consolidated Standards of Reporting Trials) diagram. EUC: enhanced usual care; SOVA: Supporting Our Valued Adolescents. EHR: electronic health record.

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