Association between age and clinical characteristics and outcomes of COVID-19

Yang Liu, Bei Mao, Shuo Liang, Jia-Wei Yang, Hai-Wen Lu, Yan-Hua Chai, Lan Wang, Li Zhang, Qiu-Hong Li, Lan Zhao, Yan He, Xiao-Long Gu, Xiao-Bin Ji, Li Li, Zhi-Jun Jie, Qiang Li, Xiang-Yang Li, Hong-Zhou Lu, Wen-Hong Zhang, Yuan-Lin Song, Jie-Ming Qu, Jin-Fu Xu, Shanghai Clinical Treatment Experts Group for COVID-19, Yang Liu, Bei Mao, Shuo Liang, Jia-Wei Yang, Hai-Wen Lu, Yan-Hua Chai, Lan Wang, Li Zhang, Qiu-Hong Li, Lan Zhao, Yan He, Xiao-Long Gu, Xiao-Bin Ji, Li Li, Zhi-Jun Jie, Qiang Li, Xiang-Yang Li, Hong-Zhou Lu, Wen-Hong Zhang, Yuan-Lin Song, Jie-Ming Qu, Jin-Fu Xu, Shanghai Clinical Treatment Experts Group for COVID-19

Abstract

Age significantly determined the clinical features and prognosis of COVID-19. The prognosis was worse in patients older than 60 years, calling for clinicians to pay more attention to patients of this age. https://bit.ly/34DTI05

Conflict of interest statement

Conflict of interest: Yang Liu has nothing to disclose. Conflict of interest: Bei Mao has nothing to disclose. Conflict of interest: Shuo Liang has nothing to disclose. Conflict of interest: Jia-Wei Yang has nothing to disclose. Conflict of interest: Hai-Wen Lu has nothing to disclose. Conflict of interest: Yan-Hua Chai has nothing to disclose. Conflict of interest: Lan Wang has nothing to disclose. Conflict of interest: Li Zhang has nothing to disclose. Conflict of interest: Qiu-Hong Li has nothing to disclose. Conflict of interest: Lan Zhao has nothing to disclose. Conflict of interest: Yan He has nothing to disclose. Conflict of interest: Xiao-Long Gu has nothing to disclose. Conflict of interest: Xiao-Bin Ji has nothing to disclose. Conflict of interest: Li Li has nothing to disclose. Conflict of interest: Zhi-Jun Jie has nothing to disclose. Conflict of interest: Qiang Li has nothing to disclose. Conflict of interest: Xiang-Yang Li has nothing to disclose. Conflict of interest: Hong-Zhou Lu has nothing to disclose. Conflict of interest: Wen-Hong Zhang has nothing to disclose. Conflict of interest: Yuan-Lin Song has nothing to disclose. Conflict of interest: Jie-Ming Qu has nothing to disclose. Conflict of interest: Jin-Fu Xu has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Comparison of clinical features and outcomes of COVID-19 between two age groups,

References

    1. Burki T. Outbreak of coronavirus disease 2019. Lancet Infect Dis 2020; 20: 292–293. doi:10.1016/S1473-3099(20)30076-1
    1. Guan WJ, Chen RC, Zhong NS. Strategies for the prevention and management of coronavirus disease 2019. Eur Respir J 2020; 55: 2000597. doi:10.1183/13993003.00597-2020
    1. Miller EJ, Linge HM. Age-related changes in immunological and physiological responses following pulmonary challenge. Int J Mol Sci 2017; 18: E1294. doi:10.3390/ijms18061294
    1. Yang X, Yu Y, Xu J, et al. . Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 2020; 8: 475–481. doi:10.1016/S2213-2600(20)30079-5
    1. Zhou F, Yu T, Du R, et al. . Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395: 1054–1062. doi:10.1016/S0140-6736(20)30566-3
    1. Wu C, Chen X, Cai Y, et al. . Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med 2020; in press [10.1001/jamainternmed.2020.0994].
    1. Du RH, Liang LR, Yang CQ, et al. . Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study. Eur Respir J 2020; 55: 2000524. doi:10.1183/13993003.00524-2020
    1. Lin L, Li TS. [Interpretation of “Guidelines for the diagnosis and treatment of novel coronavirus (2019-nCoV) infection by the National Health Commission (Trial Version 5)”]. Zhonghua Yi Xue Za Zhi 2020; 100: 805–807. doi:10.3760/cma.j.cn112137-20200205-00199
    1. Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol 2020; 92: 441–447. doi:10.1002/jmv.25689
    1. Wang D, Hu B, Hu C, et al. . Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020; 323: 1061–1069. doi:10.1001/jama.2020.1585
    1. Guan WJ, Ni ZY, Hu Y, et al. . Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020; 382: 1708–1720. doi:10.1056/NEJMoa2002032
    1. He Z, Zhao C, Dong Q, et al. . Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets. Int J Infect Dis 2005; 9: 323–330. doi:10.1016/j.ijid.2004.07.014
    1. Zhang JJ, Dong X, Cao YY, et al. . Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy 2020; in press [10.1111/all.14238].
    1. Xu YH, Dong JH, An WM, et al. . Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2. J Infect 2020; 80: 394–400. doi:10.1016/j.jinf.2020.02.017
    1. Cai H. Sex difference and smoking predisposition in patients with COVID-19. Lancet Respir Med 2020; 8: e20. doi:10.1016/S2213-2600(20)30117-X

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