A randomized controlled trial on the effect of focal thermal therapy at acupressure points treating osteoarthritis of the knee

Kevin Ki-Wai Ho, Anthony Wai-Leung Kwok, Wai-Wang Chau, S M Xia, Y L Wang, Jack Chun-Yiu Cheng, Kevin Ki-Wai Ho, Anthony Wai-Leung Kwok, Wai-Wang Chau, S M Xia, Y L Wang, Jack Chun-Yiu Cheng

Abstract

Background: Osteoarthritis of the knee is a common degenerative joint disorder in our ageing population. A combination of thermal therapy with a self-management exercise have shown a positive effect in the management of osteoarthritis of the knee. This study aimed to compare the effectiveness of topical heat pack versus focal application of heat therapy at the acupressure points in the treatment of osteoarthritis of the knee.

Methods: A randomized controlled trial was conducted in 76 patients with osteoarthritis of the knee, diagnosed by an experienced orthopedic surgeon. Following inclusion and exclusion selection, patients were randomly allocated to group 1 (Heat pack) or group 2 (Thermal gun). All patients received 30 min of treatment in each session, twice a week for 4 weeks. They also received an education program and taught home knee exercises. Outcome measurements were the visual analog scale (VAS) for pain intensity, muscle power, knee ROM, WOMAC and SF-12v2.

Results: In the Thermal gun group, function and total scores (WOMAC) and Physical Composite Scale (SF-12v2) were significantly improved after 8 sessions. Quadriceps strength was significantly improved after 8 weeks (from 4.42 to 4.63; p = 0.02). In the Heat pack group, flexion was significantly improved after 8 sessions (p = 0.02). Mean VAS scores after Heat pack treatment was consistently better (lower) than mean VAS scores after Thermal gun treatment.

Conclusion: The combination of focal thermal therapy at acupressure points is a viable conservative treatment in osteoarthritis of the knee. The pressure at the acupressure points has a synergistic benefit than topical thermal therapy alone.

Trial registration: ClinicalTrials.gov , NCT04735029 Date of registration: February 2, 2021 (Retrospectively registered).

Keywords: Acupressure; Knee osteoarthritis; Randomized controlled trial.

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
The summary of the study recruitment
Fig. 2
Fig. 2
Acupressure points around the knee. On the medial side, acupuncture points are SP10 and EX-LE4. On the lateral side, acupuncture points are ST34 and ST35
Fig. 3
Fig. 3
The workflow of the study
Fig. 4
Fig. 4
The intergroup change of WOMAC
Fig. 5
Fig. 5
Longitudinal VAS scores obtained after each session from patients treated by either thermal gun or heat pack

References

    1. Du H, Chen SL, Bao CD, Wang XD, Lu Y, Gu YY, et al. Prevalence and risk factors of knee osteoarthritis in Huang-Pu District, Shanghai, China. Rheumatol Int. 2005;25(8):585–590. doi: 10.1007/s00296-004-0492-7.
    1. Glyn-Jones S, Palmer AJ, Agricola R, Price AJ, Vincent TL, Weinans H, et al. Osteoarthritis. Lancet. 2015;386(9991):376–387. doi: 10.1016/S0140-6736(14)60802-3.
    1. Johnson VL, Hunter DJ. The epidemiology of osteoarthritis. Best Pract Res Cl Rh. 2014;28(1):5–15. doi: 10.1016/j.berh.2014.01.004.
    1. Lee J, Chang RW, Ehrlich-Jones L, Kwoh CK, Nevitt M, Semanik PA, Sharma L, Sohn MW, Song J, Dunlop DD. Sedentary behavior and physical function: objective evidence from the Osteoarthritis Initiative. Arthritis Care Res. 2015;67(3):366–373. doi: 10.1002/acr.22432.
    1. Mesci E, Icagasioglu A, Mesci N, Turgut ST. Relation of physical activity level with quality of life, sleep and depression in patients with knee osteoarthritis. Northern Clin Istanbul. 2015;2(3):215–221. doi: 10.14744/nci.2015.95867.
    1. Ho KW, Pong G, Poon WC, Chung KY, Kwok YY, Chiu KH. Progression of health-related quality of life of patients waiting for total knee arthroplasty. J Eval Clin Pract. 2020;27(1):69–74. doi: 10.1111/jep.13388.
    1. Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, Towheed T, Welch V, Wells G, Tugwell P, American College of Rheumatology American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care Res. 2012;64(4):465–474. doi: 10.1002/acr.21596.
    1. McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM, et al. OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthr Cartil. 2014;22(3):363–388. doi: 10.1016/j.joca.2014.01.003.
    1. Bjordal J. NSAIDs in osteoarthritis: irreplaceable or troublesome guidelines? Br J Sports Med. 2006;40(4):285–286. doi: 10.1136/bjsm.2005.021691.
    1. Meng ZD, Huang RZ. Topical treatment of degenerative knee osteoarthritis. Am J Med Sci. 2018;355(1):6–12. doi: 10.1016/j.amjms.2017.06.006.
    1. Kim H, Suzuki T, Saito K, Kim M, Kojima N, Ishizaki T, Yamashiro Y, Hosoi E, Yoshida H. Effectiveness of exercise with or without thermal therapy for community-dwelling elderly Japanese women with non-specific knee pain: a randomized controlled trial. Arch Gerontol Geriatr. 2013;57(3):352–359. doi: 10.1016/j.archger.2013.06.008.
    1. Yang M, Jiang L, Wang Q, Chen H, Xu G. Traditional Chinese medicine for knee osteoarthritis: an overview of systematic review. PLoS One. 2017;12(12):e0189884. doi: 10.1371/journal.pone.0189884.
    1. Yuan QL, Guo TM, Liu L, Sun F, Zhang YG. Traditional Chinese medicine for neck pain and low back pain: a systematic review and meta-analysis. PLoS One. 2015;10(2):e0117146. doi: 10.1371/journal.pone.0117146.
    1. Kohn MD, Sassoon AA, Fernando ND. Classifications in brief: Kellgren-Lawrence classification of osteoarthritis. Clin Orthop Relat Res. 2016;474(8):1886–1893. doi: 10.1007/s11999-016-4732-4.
    1. Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum. 2000;43(9):1905–1915. doi: 10.1002/1529-0131(200009)43:9<1905::AID-ANR1>;2-P.
    1. Brosseau L, Yonge KA, Robinson V, Marchand S, Judd M, Wells G, et al. Thermotherapy for treatment of osteoarthritis. Cochrane Database Syst Rev. 2003;4:CD004522. doi: 10.1002/14651858.CD004522.
    1. Li LW, Harris RE, Murphy SL, Tsodikov A, Struble L. Feasibility of a randomized controlled trial of self-administered acupressure for symptom management in older adults with knee osteoarthritis. J Altern Complement Med. 2016;22(5):396–403. doi: 10.1089/acm.2015.0231.
    1. Zhang Y, Shen CL, Peck K, Brismee JM, Doctolero S, Lo DF, et al. Training self-administered acupressure exercise among postmenopausal women with osteoarthritic knee pain: a feasibility study and lessons learned. Evid Based Complement Alternat Med. 2012;2012:570431–570439. doi: 10.1155/2012/570431.
    1. Jenkinson C, Layte R, Jenkinson D, Lawrence K, Petersen S, Paice C, Stradling J. A shorter form health survey: Can the SF-12 replicate results from the SF-36 in longitudinal studies? J Public Health Med. 1997;19(2):179–186. doi: 10.1093/oxfordjournals.pubmed.a024606.
    1. Chen YW, Wang HH. The effectiveness of acupressure on relieving pain: a systematic review. Pain Manag Nurs. 2014;15(2):539–550. doi: 10.1016/j.pmn.2012.12.005.
    1. Bazarganipour F, Taghavi SA, Allan H, Hosseini N, Khosravi A, Asadi R, Salari S, Dehghani R, Jamshidi Z, Rezaei M, Saberian M, Javedan F, Salari Z, Miri F. A randomized controlled clinical trial evaluating quality of life when using a simple acupressure protocol in women with primary dysmenorrhea. Complement Ther Med. 2017;34:10–15. doi: 10.1016/j.ctim.2017.07.004.
    1. Yildirim N, Filiz Ulusoy M, Bodur H. The effect of heat application on pain, stiffness, physical function and quality of life in patients with knee osteoarthritis. J Clin Nurs. 2010;19(7-8):1113–1120. doi: 10.1111/j.1365-2702.2009.03070.x.
    1. Konrad A, Stafilidis S, Tilp M. Effects of acute static, ballistic, and PNF stretching exercise on the muscle and tendon tissue properties. Scand J Med Sci Sports. 2017;27(10):1070–1080. doi: 10.1111/sms.12725.
    1. Al-Johani AH, Kachanathu SJ, Ramadan Hafez A, Al-Ahaideb A, Algarni AD, Meshari Alroumi A, et al. Comparative study of hamstring and quadriceps strengthening treatments in the management of knee osteoarthritis. J Phys Ther Sci. 2014;26(6):817–820. doi: 10.1589/jpts.26.817.
    1. Li LW, Harris RE, Tsodikov A, Struble L, Murphy SL. Self-acupressure for older adults with symptomatic knee osteoarthritis: a randomized controlled trial. Arthritis Care Res. 2018;70(2):221–229. doi: 10.1002/acr.23262.
    1. Dell'Isola A, Jonsson T, Ranstam J, Dahlberg LE, Ekvall Hansson E. Education, home exercise, and supervised exercise for people with hip and knee osteoarthritis as part of a nationwide implementation program: data from the Better Management of Patients With Osteoarthritis Registry. Arthritis Care Res. 2020;72(2):201-207. doi: 10.1002/acr.24033, 2.

Source: PubMed

3
S'abonner