SARS-CoV-2 and HIV-1 - a tale of two vaccines

Barton F Haynes, Barton F Haynes

Abstract

The rapid development of COVID-19 vaccines and their deployment in less than a year is a scientific and medical triumph that has raised a key question. Why do we have several SARS-CoV-2 vaccines but do not have a single HIV-1 vaccine?

Conflict of interest statement

B.F.H. has patents submitted and pending on coronavirus spike protein designs, composition and methods for their use (US patent nos 63/147,998; 63/149,541; 63/167,390), compositions comprising modified HIV envelopes (US patent PCT/US2018/034,772), and compositions comprising HIV envelopes to induce HIV antibodies (US patent provisional 62/739,701).

Figures

Fig. 1. Vaccine development for SARS-CoV-2 and…
Fig. 1. Vaccine development for SARS-CoV-2 and HIV-1.
Ab, antibody; bnAb, broadly neutralizing antibody.

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Source: PubMed

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