Foodborne illness acquired in the United States--major pathogens

Elaine Scallan, Robert M Hoekstra, Frederick J Angulo, Robert V Tauxe, Marc-Alain Widdowson, Sharon L Roy, Jeffery L Jones, Patricia M Griffin, Elaine Scallan, Robert M Hoekstra, Frederick J Angulo, Robert V Tauxe, Marc-Alain Widdowson, Sharon L Roy, Jeffery L Jones, Patricia M Griffin

Abstract

Estimates of foodborne illness can be used to direct food safety policy and interventions. We used data from active and passive surveillance and other sources to estimate that each year 31 major pathogens acquired in the United States caused 9.4 million episodes of foodborne illness (90% credible interval [CrI] 6.6-12.7 million), 55,961 hospitalizations (90% CrI 39,534-75,741), and 1,351 deaths (90% CrI 712-2,268). Most (58%) illnesses were caused by norovirus, followed by nontyphoidal Salmonella spp. (11%), Clostridium perfringens (10%), and Campylobacter spp. (9%). Leading causes of hospitalization were nontyphoidal Salmonella spp. (35%), norovirus (26%), Campylobacter spp. (15%), and Toxoplasma gondii (8%). Leading causes of death were nontyphoidal Salmonella spp. (28%), T. gondii (24%), Listeria monocytogenes (19%), and norovirus (11%). These estimates cannot be compared with prior (1999) estimates to assess trends because different methods were used. Additional data and more refined methods can improve future estimates.

Figures

Figure
Figure
Example schematic diagram of the estimation and uncertainty model used to estimate episodes of illness, hospitalizations, and deaths in the United States. Count, data (empirical distribution); Year, factor to standardize non-2006 counts to 2006 (constant); Sub, expansive factor to scale area surveillance to the entire US population (constant); Ob, expansive factor to scale outbreak counts up to outbreak plus sporadic counts (beta distribution); CS, expansive factor to scale care seekers to all ill, with severe and mild illness versions (PERT distribution); SS, expansive factor to scale submitted samples to all visits, with severe and mild illness versions (PERT distribution); PS, estimated proportion of illnesses that are severe (PERT distribution); LT, expansive factor to scale tests performed up to samples submitted (PERT distribution); LS, expansive factor to scale positive test results up to true positive specimens (PERT distribution); H, contractive factor to scale illnesses down to hospitalized illnesses (PERT distribution); D, contractive factor to scale illnesses down to deaths (PERT distribution); F, contractive factor to scale illnesses down to foodborne illnesses (PERT distribution).

References

    1. Flint JA, Van Duynhoven YT, Angulo FJ, DeLong SM, Braun P, Kirk M, et al. Estimating the burden of acute gastroenteritis, foodborne disease, and pathogens commonly transmitted by food: an international review. Clin Infect Dis. 2005;41:698–704. 10.1086/432064
    1. Kuchenmuller T, Hird S, Stein C, Kramarz P, Nanda A, Havelaar AH. Estimating the global burden of foodborne diseases—a collaborative effort. Euro Surveill. 2009;14:pii:19195. PMID: 19422776
    1. Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, et al. Food-related illness and death in the United States. Emerg Infect Dis. 1999;5:607–25. 10.3201/eid0505.990502
    1. Scallan E, Griffin PM, Angulo FJ, Tauxe RV, Hoekstra RM. Foodborne illness acquired in the United States—unspecified agents. Emerg Infect Dis. 2011;17:16–22.
    1. Powell M, Ebel E, Schlosser W. Considering uncertainty in comparing the burden of illness due to foodborne microbial pathogens. Int J Food Microbiol. 2001;69:209–15. 10.1016/S0168-1605(01)00495-0
    1. Scallan E. Activities, achievements, and lessons learned during the first 10 years of the Foodborne Diseases Active Surveillance Network: 1996–2005. Clin Infect Dis. 2007;44:718–25. 10.1086/511648
    1. US Census Bureau. Population estimates [cited 2010 March 9].
    1. Jones TF, McMillian MB, Scallan E, Frenzen PD, Cronquist AB, Thomas S, et al. A population-based estimate of the substantial burden of diarrhoeal disease in the United States; FoodNet, 1996–2003. Epidemiol Infect. 2007;135:293–301. 10.1017/S0950268806006765
    1. Scallan E, Jones TF, Cronquist A, Thomas S, Frenzen P, Hoefer D, et al. Factors associated with seeking medical care and submitting a stool sample in estimating the burden of foodborne illness. Foodborne Pathog Dis. 2006;3:432–8. 10.1089/fpd.2006.3.432
    1. Voetsch AC, Angulo FJ, Rabatsky-Ehr T, Shallow S, Cassidy M, Thomas SM, et al. Laboratory practices for stool-specimen culture for bacterial pathogens, including Escherichia coli O157:H7, in the FoodNet sites, 1995–2000. Clin Infect Dis. 2004;38(Suppl 3):S190–7. 10.1086/381586
    1. Jones JL, Lopez A, Wahlquist SP, Nadle J, Wilson M. Survey of clinical laboratory practices for parasitic diseases. Clin Infect Dis. 2004;38(Suppl 3):S198–202. 10.1086/381587
    1. Jones JL, Kruszon-Moran D, Sanders-Lewis K, Wilson M. Toxoplasma gondii infection in the United States, 1999–2004, decline from the prior decade. Am J Trop Med Hyg. 2007;77:405–10.
    1. World Health Organization. Toxoplasmosis. Technical report series no. 431. Geneva: The Organization; 1969.
    1. Widdowson MA, Meltzer MI, Zhang X, Bresee JS, Parashar UD, Glass RI. Cost-effectiveness and potential impact of rotavirus vaccination in the United States. Pediatrics. 2007;119:684–97. 10.1542/peds.2006-2876
    1. Wheeler JG, Sethi D, Cowden JM, Wall PG, Rodrigues LC, Tompkins DS, et al. Study of infectious intestinal disease in England: rates in the community, presenting to general practice, and reported to national surveillance. The Infectious Intestinal Disease Study Executive. BMJ. 1999;318:1046–50.
    1. de Wit MA, Koopmans MP, Kortbeek LM, Wannet WJ, Vinje J, van Leusden F, et al. Sensor, a population-based cohort study on gastroenteritis in the Netherlands: incidence and etiology. Am J Epidemiol. 2001;154:666–74. 10.1093/aje/154.7.666
    1. Marshall JA, Hellard ME, Sinclair MI, Fairley CK, Cox BJ, Catton MG, et al. Incidence and characteristics of endemic Norwalk-like virus–associated gastroenteritis. J Med Virol. 2003;69:568–78. 10.1002/jmv.10346
    1. Amar CF, East CL, Gray J, Iturriza-Gomara M, Maclure EA, McLauchlin J. Detection by PCR of eight groups of enteric pathogens in 4,627 faecal samples: re-examination of the English case–control Infectious Intestinal Disease Study (1993–1996). Eur J Clin Microbiol Infect Dis. 2007;26:311–23. 10.1007/s10096-007-0290-8
    1. Dennehy PH, Nelson SM, Spangenberger S, Noel JS, Monroe SS, Glass RI. A prospective case–control study of the role of astrovirus in acute diarrhea among hospitalized young children. J Infect Dis. 2001;184:10–5. 10.1086/321007
    1. Klein EJ, Boster DR, Stapp JR, Wells JG, Qin X, Clausen CR, et al. Diarrhea etiology in a children's hospital emergency department: a prospective cohort study. Clin Infect Dis. 2006;43:807–13. 10.1086/507335
    1. Vose D. Risk analysis. A quantitative guide. 2nd ed. Chichester (UK): John Wiley & Sons; 2000.
    1. Tauxe RV. Emerging foodborne pathogens. Int J Food Microbiol. 2002;78:31–41. 10.1016/S0168-1605(02)00232-5
    1. Adak GK, Meakins SM, Yip H, Lopman BA, O’Brien SJ. Disease risks from foods, England and Wales, 1996–2000. Emerg Infect Dis. 2005;11:365–72.
    1. Hall G, Kirk MD, Becker N, Gregory JE, Unicomb L, Millard G, et al. Estimating foodborne gastroenteritis, Australia. Emerg Infect Dis. 2005;11:1257–64.
    1. Simonsen J, Teunis P, Van Pelt W, Van Duynhoven Y, Krogfelt KA, Sadkowska-Todys M, et al. Usefulness of seroconversion rates for comparing infection pressures between countries. [Epub ahead of print]. Epidemiol Infect. 2010;:1–8.
    1. St Louis ME, Peck SH, Bowering D, Morgan GB, Blatherwick J, Banerjee S, et al. Botulism from chopped garlic: delayed recognition of a major outbreak. Ann Intern Med. 1988;108:363–8.
    1. Sobel J, Malavet M, John S. Outbreak of clinically mild botulism type E illness from home-salted fish in patients presenting with predominantly gastrointestinal symptoms. Clin Infect Dis. 2007;45:e14–6. 10.1086/518993
    1. Dalton CB, Austin CC, Sobel J, Hayes PS, Bibb WF, Graves LM, et al. An outbreak of gastroenteritis and fever due to Listeria monocytogenes in milk. N Engl J Med. 1997;336:100–5. 10.1056/NEJM199701093360204
    1. Pinner RW, Teutsch SM, Simonsen L, Klug LA, Graber JM, Clarke MJ, et al. Trends in infectious diseases mortality in the United States. JAMA. 1996;275:189–93. 10.1001/jama.275.3.189
    1. Patel MM, Widdowson MA, Glass RI, Akazawa K, Vinje J, Parashar UD. Systematic literature review of role of noroviruses in sporadic gastroenteritis. Emerg Infect Dis. 2008;14:1224–31. 10.3201/eid1408.071114
    1. Jansen A, Stark K, Kunkel J, Schreier E, Ignatius R, Liesenfeld O, et al. Aetiology of community-acquired, acute gastroenteritis in hospitalised adults: a prospective cohort study. BMC Infect Dis. 2008;8:143. 10.1186/1471-2334-8-143
    1. Badger GF, Curtiss C, Dingle JH, Hodges RG, Jordan WS Jr, McCorkle LP. A study of illness in a group of Cleveland families. XI. The occurrence of gastrointestinal symptoms. Am J Hyg. 1956;64:349–56.
    1. Monto AS, Koopman JS. The Tecumseh Study. XI. Occurrence of acute enteric illness in the community. Am J Epidemiol. 1980;112:323–33.
    1. Centers for Disease Control and Prevention. Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food—10 states, 2009. MMWR Morb Mortal Wkly Rep. 2010;59:418–22.
    1. Pires SM, Evers EG, van Pelt W, Ayers T, Scallan E, Angulo FJ, et al. Attributing the human disease burden of foodborne infections to specific sources. Foodborne Pathog Dis. 2009;6:417–24. 10.1089/fpd.2008.0208
    1. Crump JA, Sulka AC, Langer AJ, Schaben C, Crielly AS, Gage R, et al. An outbreak of Escherichia coli O157:H7 infections among visitors to a dairy farm. N Engl J Med. 2002;347:555–60. 10.1056/NEJMoa020524
    1. Blanton LH, Adams SM, Beard RS, Wei G, Bulens SN, Widdowson MA, et al. Molecular and epidemiologic trends of caliciviruses associated with outbreaks of acute gastroenteritis in the United States, 2000–2004. J Infect Dis. 2006;193:413–21. 10.1086/499315

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