Benefits and risks of childhood immunisations in developing countries

J D Holden, J D Holden

Abstract

The ratio of benefit to harm from an imaginary, modest immunisation programme in a developing country and the numbers of lives likely to be saved and severe handicaps prevented have been estimated. Immunisation is much more likely to benefit children than to harm them, and health workers can be confidently encouraged not to withhold the benefits of immunisation from most children.

PIP: The ratio of benefit to harm an imaginary, modest immunization program in a developing country and the numbers of lives likely to be saved and severe handicaps prevented are estimated. Immunization is much more likely to benefit children than to harm them, and health workers can be confidently encouraged not to withhold the benefits of immunization from most children. The UN target date for immunization to be available to all the world's children is 1990. Benefits and risks of a typical program in a developing country are calculated for diphtheria, tetanus, pertussis, polio, and measles. Such a program could be expected to save about 45 lives a month and prevent about 12 children being left with a serious handicap each month. In contrast it may cause 1 death over 22 years and 1 serious handicap every 7 1/2 years.

References

    1. Bull World Health Organ. 1966;34(1):71-104
    1. Bull World Health Organ. 1955;13(3):367-80
    1. J Indian Med Assoc. 1970 Dec 1;55(11):371-5
    1. Trop Geogr Med. 1974 Mar;26(1):39-44
    1. Br Med J. 1977 Apr 16;1(6067):1009-12
    1. East Afr Med J. 1978 Jan;55(1):36-8
    1. Bull World Health Organ. 1978;56(5):773-80
    1. Indian J Med Res. 1978 Oct;68 Suppl:26-37
    1. Lancet. 1979 Jul 28;2(8135):188-90
    1. Br Med J (Clin Res Ed). 1981 May 16;282(6276):1595-9
    1. JAMA. 1982 Jan 1;247(1):40-2
    1. Bull World Health Organ. 1981;59(6):901-8
    1. Arch Phys Med Rehabil. 1982 Jul;63(7):332-4
    1. Lancet. 1983 Apr 30;1(8331):972-5
    1. Lancet. 1984 Dec 1;2(8414):1240-2
    1. Br Med J (Clin Res Ed). 1986 Feb 22;292(6519):531-3
    1. Arch Dermatol. 1987 Jan;123(1):62-5
    1. AMA Arch Intern Med. 1958 May;101(5):881-93
    1. Trop Geogr Med. 1970 Sep;22(3):303-6

Source: PubMed

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