What explains the different rates of human papillomavirus vaccination among adolescent males and females in the United States?

Yoonyoung Choi, Efe Eworuke, Richard Segal, Yoonyoung Choi, Efe Eworuke, Richard Segal

Abstract

Purpose: To identify factors that explain differences in HPV vaccination rates for male and female adolescents and to determine self-reported barriers by parents affecting vaccination decisions.

Methods: The sample included adolescents 13-17 years old with a vaccination record documented in the 2012 and 2013 National Immunization Survey-Teen dataset. A logistic regression model was developed with 13 socio-demographic factors and survey year, along with significant interaction pairs with gender.

Results: Subjects included 20,355 and 18,350 adolescent boys and girls, respectively. About half of the females (56%) received at least one dose of HPV vaccine, compared to 28% of males. Several factors differed between males and females, including higher vaccination rates among non-Hispanic Black males and lower vaccination rates for non-Hispanic Black females compared to Whites; and a stronger association with health care provider recommendation among males. The most common parental reasons for not vaccinating their children included 'not recommended by a health care provider' for males (24%), and 'unnecessary' for females (18%).

Conclusion: We found a significant gender interaction with several socio-demographic variables in predicting vaccination uptake. These gender differences may be partially an artifact of timing, because male vaccination became routine approximately five years after female vaccination.

Keywords: Adolescent health; Gender interaction; Human papillomavirus; NIS-Teen; Vaccination.

Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

References

    1. Palefsky J.M. Human papillomavirus-related disease in men: not just a women׳s issue. J. Adolesc. Health. 2010;46:S12–S19.
    1. Centers for Disease Control and Prevention (CDC) Quadrivalent human papillomavirus vaccine recommendations of the advisory committee on immunization practices (ACIP), 2007. Morb. Mortal. Wkly. Rep. 2007;56:1–24.
    1. Centers for Disease Control and Prevention (CDC) Recommendations on the use of quadrivalent human papillomavirus vaccine in males—Advisory Committee on Immunization Practices (ACIP), 2011. Morb. Mortal. Wkly. Rep. 2011;60:1705–1708.
    1. Gilkey M.B., Moss J.L., McRee A.L., Brewer N.T. Do Correl. HPV. 2012;30:5928–5934.
    1. Allen J.D., Othus M.K., Shelton R.C., Li Y., Norman N., Tom L. Parental decision making about the HPV vaccine. Cancer Epidemiol. Biomark. Prev. 2010;19:2187–2198.
    1. Centers for Disease Control and Prevention (CDC), HPV Vaccine-Questions & Answers Web sites, Available at: (accessed 22.02.14).
    1. Perkins R.B., Apte G., Marquez C., Porter C., Belizaire M., Clark J.A. Factors affecting human papillomavirus vaccine use among White, Black and Latino parents of sons. Pediatr. Infect. Dis. J. 2013;32:e38–e44.
    1. Cates J.R., Brewer N.T., Fazekas K.I., Mitchell C.E., Smith J.S. Racial differences in HPV knowledge, HPV vaccine acceptability, and related beliefs among rural, southern women. J Rural. Health. 2009;25:93–97.
    1. Thomas T.L., Strickland O., Diclemente R., Higgins M. An opportunity for cancer prevention during preadolescence and adolescence: stopping human papillomavirus (HPV)-related cancer through HPV vaccination. J. Adolesc. Health. 2013;52:S60–S68.
    1. Centers for Disease Control and Prevention (CDC), About the National Immunization Survey Websites, Available at: (accessed 12.05.14).
    1. U.S. Department of Health and Human Services (DHHS), National Center for Health Statistics, The 2012 National Immunization Survey-Teen, Centers for Disease Control and Prevention, Hyattsville, MD, 2013.

    1. U.S. Department of Health and Human Services (DHHS), National Center for Health Statistics, The 2013 National Immunization Survey-Teen, Centers for Disease Control and Prevention, Hyattsville, MD, 2014.

    1. Jain N., Singleton J.A., Montgomery M., Skalland B. Determining accurate vaccination coverage rates for adolescents: the National Immunization Survey-Teen 2006. Public Health Rep. 2009;124:642–651.
    1. Centers for Disease Control and Prevention (CDC), Finding and Paying for Vaccines web sites, Available at: (accessed 28.06.14).
    1. Association of Maternal and Child Health Programs (AMCHP) Association of Maternal and Child Health Programs; Washington, DC: 2007. The HPV Vaccine: Background, Coverage & Benefits. AMCHP FACT SHEET.
    1. National Cancer Institute (NCI), Human Papillomavirus (HPV) Vaccines Websites, Available at: (accessed 23.04.14).
    1. Peduzzi P., Concato J., Kemper E., Holford T.R., Feinstein A.R. A simulation study of the number of events per variable in logistic regression analysis. J Clin. Epidemiol. 1996;49:1373–1379.
    1. C. Salmond, Fitting complex models using Health Survey data, Available at: (accessed 20.10.14).
    1. Centers for Disease Control and Prevention (CDC) Human papillomavirus vaccination coverage among adolescent girls, 2007–2012, and postlicensure vaccine safety monitoring, 2006–2013—United States, 2013. Morb. Mortal. Wkly. Rep. 2013;62:591–595.
    1. Elam-Evans L.D., Yankey D., Jeyarajah J., Singleton J.A., Curtis R.C., MacNeil J. National, regional, state, and selected local area vaccination coverage among adolescents aged 13-–17 years—United States, 2013. Morb. Mortal. Wkly. Rep. 2014;63:625–633.
    1. Stokley S., Jeyarajah J., Yankey D., Cano M., Gee J., Roark J. Human papillomavirus vaccination coverage among adolescents, 2007–2013, and postlicensure vaccine safety monitoring, 2006–2014--United States. Morb. Mortal. Wkly. Rep. 2014;63:620–624.
    1. Marlow L.A., Wardle J., Waller J. Attitudes to HPV vaccination among ethnic minority mothers in the UK: an exploratory qualitative study. Hum. Vaccin. 2009;5:105–110.
    1. Reiter P.L., Gilkey M.B., Brewer N.T. HPV vaccination among adolescent males: results from the National Immunization Survey-Teen. Vaccine. 2013;31:2816–2821.
    1. Dempsey A.F., Butchart A., Singer D., Clark S., Davis M. Factors associated with parental intentions for male human papillomavirus vaccination: results of a national survey. Sex. Transm. Dis. 2011;38:769–776.
    1. Polonijo A.N., Carpiano R.M. Social inequalities in adolescent human papillomavirus (HPV) vaccination: a test of fundamental cause theory. Soc. Sci. Med. 2013;82:115–125.
    1. Dorell C.G., Yankey D., Santibanez T.A., Markowitz L.E. Human papillomavirus vaccination series initiation and completion, 2008–2009. Pediatrics. 2011;128:830–839.
    1. Perkins R.B., Tipton H., Shu E., Marquez C., Belizaire M., Porter C. Attitudes toward HPV vaccination among low-income and minority parents of sons: a qualitative analysis. Clin. Pediatr. 2013;52:231–240.
    1. Centers for Disease Control and Prevention (CDC) Human papillomavirus-associated cancers—United States, 2004–2008. Morb. Mortal. Wkly. Rep. 2012;61:258–261.
    1. Kann L., Kinchen S., Shanklin S.L., Flint K.H., Kawkins J., Harris W.A. Youth risk behavior surveillance—United States, 2013. MMWR Surveill. Summ. 2014;63(Suppl. 4):1–168.

    1. GARDASIL [package insert], Merck & Co, Whitehouse Station, NJ, 2011.

    1. Perkins R.B., Brogly S.B., Adams W.G., Freund K.M. Correlates of human papillomavirus vaccination rates in low-income, minority adolescents: a multicenter study. J. Womens Health. 2012;21:813–820.
    1. Dorell C.G., Jain N., Yankey D. Validity of parent-reported vaccination status for adolescents aged 13–17 years: National Immunization Survey-Teen, 2008. Public Health Rep. 2011;126(Suppl. 2):60–69.
    1. Ojha R.P., Tota J.E., Offutt-Powell T.N., Klosky J.L., Ashokkumar R., Gurney J.G. The accuracy of human papillomavirus vaccination status based on adult proxy recall or household immunization records for adolescent females in the United States: results from the National Immunization Survey-Teen. Ann. Epidemiol. 2013;23:281–285.
    1. Hanley S.J., Yoshioka E., Ito Y., Konno R., Hayashi Y., Kishi R. Acceptance of and attitudes towards human papillomavirus vaccination in Japanese mothers of adolescent girls. Vaccine. 2012;30:5740–5747.

Source: PubMed

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