Human papillomavirus (HPV) vaccination is cancer prevention for childhood cancer survivors

Heather M Brandt, Deanna Kepka, Anne C Kirchhoff, Casey L Daniel, Neel S Bhatt, Heather M Brandt, Deanna Kepka, Anne C Kirchhoff, Casey L Daniel, Neel S Bhatt

Abstract

Childhood cancer survivors are at high risk for developing human papillomavirus (HPV)-associated subsequent neoplasms. Henderson et al., 2021 identified risk factors for subsequent HPV-associated malignant neoplasms among enrollees in the Childhood Cancer Survivor Study. The exacerbated risk of subsequent HPV cancers found in the study underscores the need for more stringent surveillance and tracking to inform intervention approaches to ensure maximal protection. In addition, HPV vaccination must be prioritized as part of transitional care and survivorship planning. Limited sources of data on survivor practices and outcomes results in limited information to develop guidelines and provide childhood cancer survivors with information on preventing subsequent HPV cancers. Improved efforts are needed to increase HPV vaccination and HPV-related surveillance among childhood cancer survivors to prevent subsequent neoplasms.

Keywords: HPV vaccination; HPV vaccine; childhood cancer; human papillomavirus; oncology; survivorship; survivorship guidelines; vaccination.

References

    1. Henderson TO, Fowler B, Hamann H et al. Subsequent malignant neoplasms in the Childhood Cancer Survivor Study: Occurrence of cancer types where human papillomavirus is an established etiologic risk factor. Cancer. 2021. TO BE ADDED
    1. Ojha RP, Tota JE, Offutt-Powell TN, et al. Human papillomavirus-associated subsequent malignancies among long-term survivors of pediatric and young adult cancers. PLoS One. 2013;8(8):e70349. Published 2013 Aug 5. doi:10.1371/journal.pone.0070349
    1. Meites E, Szilagyi PG, Chesson HW, Unger ER, Romero JR, Markowitz LE. Human Papillomavirus Vaccination for Adults: Updated Recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2019;68(32):698–702. Published 2019 Aug 16. doi:10.15585/mmwr.mm6832a3
    1. Meites E, Kempe A, Markowitz LE. Use of a 2-Dose Schedule for Human Papillomavirus Vaccination - Updated Recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2016;65(49):1405–1408. Published 2016 Dec 16. doi:10.15585/mmwr.mm6549a5
    1. Cherven B, Landier W. Human Papillomavirus Vaccine Is Crucial for Adolescent and Young Adult Cancer Survivors. J Adolesc Young Adult Oncol. 2017;6(3):385–387. doi:10.1089/jayao.2017.0014
    1. Klosky JL, Gamble HL, Spunt SL, Randolph ME, Green DM, Hudson MM. Human papillomavirus vaccination in survivors of childhood cancer. Cancer. 2009;115(24):5627–5636. doi:10.1002/cncr.24669
    1. Elam-Evans LD, Yankey D, Singleton JA, et al. National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13–17 Years - United States, 2019. MMWR Morb Mortal Wkly Rep. 2020;69(33):1109–1116. Published 2020 Aug 21. doi:10.15585/mmwr.mm6933a1
    1. Klosky JL, Hudson MM, Chen Y, et al. Human Papillomavirus Vaccination Rates in Young Cancer Survivors. J Clin Oncol. 2017;35(31):3582–3590. doi:10.1200/JCO.2017.74.1843
    1. Children’s Oncology Group. Long-term follow-up guidelines for survivors of childhood, adolescent, and young adult cancers. October 2018 (Version 5.0). Accessed August 1, 2021.
    1. Klosky JL, Russell KM, Simmons JL, et al. Medical and sociodemographic factors associated with human papillomavirus (HPV) vaccination adherence among female survivors of childhood cancer. Pediatr Blood Cancer. 2015;62(9):1630–1636. doi:10.1002/pbc.25539
    1. York JM, Klosky JL, Chen Y, et al. Patient-Level Factors Associated With Lack of Health Care Provider Recommendation for the Human Papillomavirus Vaccine Among Young Cancer Survivors. J Clin Oncol. 2020;38(25):2892–2901. doi:10.1200/JCO.19.02026
    1. Imburgia TM, Shew ML, Gravitt PE, Katzenellenbogen RA. Considerations for Child Cancer Survivors and Immunocompromised Children to Prevent Secondary HPV-associated Cancers. Transplantation. 2021;105(4):736–742. doi:10.1097/TP.0000000000003444
    1. Temkin SM, Seibel NL. Are we missing an opportunity for cancer prevention? Human papillomavirus vaccination for survivors of pediatric and young adult cancers. Cancer. 2015;121(19):3395–3402. doi:10.1002/cncr.29515
    1. Warner EL, Vaca Lopez PL, Kepka D, et al. Influence of provider recommendations to restart vaccines after childhood cancer on caregiver intention to vaccinate. J Cancer Surviv. 2020;14(5):757–767. doi:10.1007/s11764-020-00890-y
    1. Cherven B, Castellino SM, Chen Y, et al. Intent and subsequent initiation of human papillomavirus vaccine among young cancer survivors. Cancer. 2019;125(21):3810–3817. doi:10.1002/cncr.32379
    1. Klosky JL, Favaro B, Peck KR, et al. Prevalence and predictors of human papillomavirus (HPV) vaccination among young women surviving childhood cancer. J Cancer Surviv. 2016;10(3):449–456. doi:10.1007/s11764-015-0495-2
    1. Waters AR, Mann K, Vaca Lopez PL, Kepka D, Wu YP, Kirchhoff AC. HPV Vaccine Experiences and Preferences Among Young Adult Cancer Survivors and Caregivers of Childhood Cancer Survivors [published online ahead of print, 2021 Mar 19]. J Cancer Educ. 2021;10.1007/s13187–021-01992–6. doi:10.1007/s13187-021-01992-6
    1. Kirchhoff AC, Mann K, Warner EL, et al. HPV vaccination knowledge, intentions, and practices among caregivers of childhood cancer survivors. Hum Vaccin Immunother. 2019;15(7–8):1767–1775. doi:10.1080/21645515.2019.1619407
    1. Cherven B, Klosky JL, Chen Y, et al. Sexual behaviors and human papillomavirus vaccine non-initiation among young adult cancer survivors [published online ahead of print, 2021 Feb 6]. J Cancer Surviv. 2021;10.1007/s11764–021-01000–2. doi:10.1007/s11764-021-01000-2
    1. Saraiya M, Unger ER, Thompson TD, et al. US assessment of HPV types in cancers: implications for current and 9-valent HPV vaccines. J Natl Cancer Inst. 2015;107(6):djv086. Published 2015 Apr 29. doi:10.1093/jnci/djv086
    1. National Cancer Institute. Childhood Cancer Data Initiative. Accessed August 1, 2021.

Source: PubMed

Sponsors et collaborateurs

Les conditions médicales

Interventions en matière de drogue

3
S'abonner