Determinants of the COVID-19 vaccine hesitancy spectrum

Rachael Piltch-Loeb, Diana R Silver, Yeerae Kim, Hope Norris, Elizabeth McNeill, David M Abramson, Rachael Piltch-Loeb, Diana R Silver, Yeerae Kim, Hope Norris, Elizabeth McNeill, David M Abramson

Abstract

Vaccine hesitancy remains an issue in the United States. This study conducted an online survey [N = 3,013] using the Social Science Research Solution [SSRS] Opinion Panel web panelists, representative of U.S. adults age 18 and older who use the internet, with an oversample of rural-dwelling and minority populations between April 8 and April 22, 2021- as vaccine eligibility opened to the country. We examined the relationship between COVID-19 exposure and socio-demographics with vaccine intentions [eager-to-take, wait-and-see, undecided, refuse] among the unvaccinated using multinomial logistic regressions [ref: fully/partially vaccinated]. Results showed vaccine intentions varied by demographic characteristics and COVID-19 experience during the period that eligibility for the vaccine was extended to all adults. At the time of the survey approximately 40% of respondents were unvaccinated; 41% knew someone who had died of COVID-19, and 38% had experienced financial hardship as a result of the pandemic. The vaccinated were more likely to be highly educated, older adults, consistent with the United States initial eligibility criteria. Political affiliation and financial hardship experienced during the pandemic were the two most salient factors associated with being undecided or unwilling to take the vaccine.

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1

References

    1. CDC. Trends in Number of COVID-19 Vaccinations in the US [Internet]. Atlanta, GA: Centers for Disease Control and Prevention; 2021. [updated 2021 Aug 4; cited 2021 Aug 3]. .
    1. SteelFisher GK, Blendon RJ, Caporello H. An Uncertain Public—Encouraging Acceptance of Covid-19 Vaccines. N Engl J Med. 2021;384[16]:1483–7. doi: 10.1056/NEJMp2100351
    1. WHO. Global Vaccine Action Plan [Internet]. Geneva: World Health Organization; 2011. [cited 2021 August 3]. .
    1. Peretti-Watel P, Larson HJ, Ward JK, Schulz WS, Verger P. Vaccine hesitancy: clarifying a theoretical framework for an ambiguous notion. PLoS Curr. 2015;7.
    1. Gerussi V, Peghin M, Palese A, Bressan V, Visintini E, Bontempo G, et al.. Vaccine Hesitancy among Italian Patients Recovered from COVID-19 Infection towards Influenza and Sars-Cov-2 Vaccination. Vaccines [Basel]. 2021;9[2]. doi: 10.3390/vaccines9020172
    1. Ahmed N, Quinn SC, Hancock GR, Freimuth VS, Jamison A. Social media use and influenza vaccine uptake among White and African American adults. Vaccine. 2018;36[49]:7556–61. doi: 10.1016/j.vaccine.2018.10.049
    1. Galarce EM, Minsky S, Viswanath K. Socioeconomic status, demographics, beliefs and A[H1N1] vaccine uptake in the United States. Vaccine. 2011;29[32]:5284–9. doi: 10.1016/j.vaccine.2011.05.014
    1. Hwang J. Health Information Sources and the Influenza Vaccination: The Mediating Roles of Perceived Vaccine Efficacy and Safety. J Health Commun. 2020;25[9]:727–35. doi: 10.1080/10810730.2020.1840675
    1. Kwok KO, Li KK, Wei WI, Tang A, Wong SYS, Lee SS. Influenza vaccine uptake, COVID-19 vaccination intention and vaccine hesitancy among nurses: A survey. Int J Nurs Stud. 2020;114:103854. doi: 10.1016/j.ijnurstu.2020.103854
    1. Ryan KA, Filipp SL, Gurka MJ, Zirulnik A, Thompson LA. Understanding influenza vaccine perspectives and hesitancy in university students to promote increased vaccine uptake. Heliyon. 2019;5[10]:e02604. doi: 10.1016/j.heliyon.2019.e02604
    1. Suryadevara M, Bonville CA, Rosenbaum PF, Domachowske JB. Influenza vaccine hesitancy in a low-income community in central New York State. Hum Vaccin Immunother. 2014;10[7]:2098–103. doi: 10.4161/hv.28803
    1. Karpman M, Kenney GM, Zuckerman S, Gonzalez D, Courtot B. Confronting COVID-19 vaccine hesitancy among nonelderly adults. Robert Wood Johnson Foundation and Urban Institute. 2021.
    1. Khubchandani J, Sharma S, Price JH, Wiblishauser MJ, Sharma M, Webb FJ. COVID-19 Vaccination Hesitancy in the United States: A Rapid National Assessment. J Community Health. 2021;46[2]:270–7. doi: 10.1007/s10900-020-00958-x
    1. Olagoke AA, Olagoke OO, Hughes AM. Intention to Vaccinate Against the Novel 2019 Coronavirus Disease: The Role of Health Locus of Control and Religiosity. J Relig Health. 2021;60[1]:65–80. doi: 10.1007/s10943-020-01090-9
    1. Viswanath K, Bekalu M, Dhawan D, Pinnamaneni R, Lang J, McLoud R. Individual and social determinants of COVID-19 vaccine uptake. BMC Public Health. 2021;21[1]:818. doi: 10.1186/s12889-021-10862-1
    1. Roberts HA, Clark DA, Kalina C, Sherman C, Brislin S, Heitzeg MM, et al.. To vax or not to vax: Predictors of anti-vax attitudes and COVID-19 vaccine hesitancy prior to widespread vaccine availability. Plos one. 2022;17[2]:e0264019. doi: 10.1371/journal.pone.0264019
    1. Eysenbach G. Improving the Quality of Web Surveys: The Checklist for Reporting Results of Internet E-Surveys [CHERRIES]. J Med Internet Res. 2004;6[3]:e34. doi: 10.2196/jmir.6.3.e34
    1. Belsley DA, Kuh E, Welsch RE. Regression diagnostics: Identifying influential data and sources of collinearity. New York: John Wiley & Sons; 1980. 292 p.
    1. Diesel J, Sterrett N, Dasgupta S, Kriss JL, Barry V, Esschert KV, et al.. COVID-19 vaccination coverage among adults—United States, December 14, 2020–May 22, 2021. Morbidity and Mortality Weekly Report. 2021;70[25]:922. doi: 10.15585/mmwr.mm7025e1
    1. Lo Moro G, Cugudda E, Bert F, Raco I, Siliquini R. Vaccine Hesitancy and Fear of COVID-19 Among Italian Medical Students: A Cross-Sectional Study. Journal of Community Health. 2022:1–9.
    1. Zychlinsky Scharff A, Paulsen M, Schaefer P, Tanisik F, Sugianto RI, Stanislawski N, et al.. Students’ age and parental level of education influence COVID-19 vaccination hesitancy. European journal of pediatrics. 2021:1–6. doi: 10.1007/s00431-021-04343-1
    1. Litaker JR, Tamez N, Lopez Bray C, Durkalski W, Taylor R. Sociodemographic Factors Associated with Vaccine Hesitancy in Central Texas Immediately Prior to COVID-19 Vaccine Availability. International Journal of Environmental Research and Public Health. 2022;19[1]:368.
    1. Khairat S, Zou B, Adler-Milstein J. Factors and Reasons Associated with Low COVID-19 Vaccine Uptake among Highly Hesitant Communities in the US. American journal of infection control. 2022. doi: 10.1016/j.ajic.2021.12.013
    1. Okoli GN, Lam OLT, Racovitan F, Reddy VK, Righolt CH, Neilson C, et al.. Seasonal influenza vaccination in older people: A systematic review and meta-analysis of the determining factors. PLOS ONE. 2020;15[6]:e0234702. doi: 10.1371/journal.pone.0234702
    1. Schmid P, Rauber D, Betsch C, Lidolt G, Denker ML. Barriers of Influenza Vaccination Intention and Behavior—A Systematic Review of Influenza Vaccine Hesitancy, 2005–2016. PLoS One. 2017;12[1]:e0170550. doi: 10.1371/journal.pone.0170550
    1. Chu A, Gupta V, Unni EJ. Utilizing the Theory of Planned Behavior to determine the intentions to receive the influenza vaccine during COVID-19: A cross-sectional survey of US adults. Preventive Medicine Reports. 2021;23:101417. doi: 10.1016/j.pmedr.2021.101417
    1. Kiviniemi MT, Orom H, Hay JL, Waters EA. Prevention is political: political party affiliation predicts perceived risk and prevention behaviors for COVID-19. BMC public health. 2022;22[1]:1–9.
    1. Fowler EF, Gollust SE. The Content and Effect of Politicized Health Controversies. The ANNALS of the American Academy of Political and Social Science. 2015;658[1]:155–71.
    1. Quinn SC, Jamison AM, Freimuth VS. Measles outbreaks and public attitudes towards vaccine exemptions: some cautions and strategies for addressing vaccine hesitancy. Human Vaccines & Immunotherapeutics. 2020;16[5]:1050–4. doi: 10.1080/21645515.2019.1646578
    1. Bolsen T, Palm R. Politicization and COVID-19 vaccine resistance in the US. Progress in Molecular Biology and Translational Science. 2021.
    1. Jennings W, Stoker G, Bunting H, Valgarðsson VO, Gaskell J, Devine D, et al.. Lack of trust, conspiracy beliefs, and social media use predict COVID-19 vaccine hesitancy. Vaccines. 2021;9[6]:593. doi: 10.3390/vaccines9060593
    1. Slovic P. Perception of risk. Science. 1987;236[4799]:280–5. doi: 10.1126/science.3563507
    1. Ofei-Dodoo S, Kellerman R, Russell T. Family Physicians’ Perception of the New mRNA COVID-19 Vaccines. The Journal of the American Board of Family Medicine. 2021;34[5]:898–906. doi: 10.3122/jabfm.2021.05.210052
    1. Olanipekun T, Abe T, Effoe V, Kagbo-Kue S, Chineke I, Ivonye C, et al.. Attitudes and perceptions towards coronavirus disease 2019 [COVID-19] vaccine acceptance among recovered African American patients. Journal of General Internal Medicine. 2021;36[7]:2186–8. doi: 10.1007/s11606-021-06787-5
    1. Violette R, Pullagura GR. Vaccine hesitancy: Moving practice beyond binary vaccination outcomes in community pharmacy. Can Pharm J [Ott]. 2019;152[6]:391–4. doi: 10.1177/1715163519878745

Source: PubMed

3
S'abonner