First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020

Gianfranco Spiteri, James Fielding, Michaela Diercke, Christine Campese, Vincent Enouf, Alexandre Gaymard, Antonino Bella, Paola Sognamiglio, Maria José Sierra Moros, Antonio Nicolau Riutort, Yulia V Demina, Romain Mahieu, Markku Broas, Malin Bengnér, Silke Buda, Julia Schilling, Laurent Filleul, Agnès Lepoutre, Christine Saura, Alexandra Mailles, Daniel Levy-Bruhl, Bruno Coignard, Sibylle Bernard-Stoecklin, Sylvie Behillil, Sylvie van der Werf, Martine Valette, Bruno Lina, Flavia Riccardo, Emanuele Nicastri, Inmaculada Casas, Amparo Larrauri, Magdalena Salom Castell, Francisco Pozo, Rinat A Maksyutov, Charlotte Martin, Marc Van Ranst, Nathalie Bossuyt, Lotta Siira, Jussi Sane, Karin Tegmark-Wisell, Maria Palmérus, Eeva K Broberg, Julien Beauté, Pernille Jorgensen, Nick Bundle, Dmitriy Pereyaslov, Cornelia Adlhoch, Jukka Pukkila, Richard Pebody, Sonja Olsen, Bruno Christian Ciancio, Gianfranco Spiteri, James Fielding, Michaela Diercke, Christine Campese, Vincent Enouf, Alexandre Gaymard, Antonino Bella, Paola Sognamiglio, Maria José Sierra Moros, Antonio Nicolau Riutort, Yulia V Demina, Romain Mahieu, Markku Broas, Malin Bengnér, Silke Buda, Julia Schilling, Laurent Filleul, Agnès Lepoutre, Christine Saura, Alexandra Mailles, Daniel Levy-Bruhl, Bruno Coignard, Sibylle Bernard-Stoecklin, Sylvie Behillil, Sylvie van der Werf, Martine Valette, Bruno Lina, Flavia Riccardo, Emanuele Nicastri, Inmaculada Casas, Amparo Larrauri, Magdalena Salom Castell, Francisco Pozo, Rinat A Maksyutov, Charlotte Martin, Marc Van Ranst, Nathalie Bossuyt, Lotta Siira, Jussi Sane, Karin Tegmark-Wisell, Maria Palmérus, Eeva K Broberg, Julien Beauté, Pernille Jorgensen, Nick Bundle, Dmitriy Pereyaslov, Cornelia Adlhoch, Jukka Pukkila, Richard Pebody, Sonja Olsen, Bruno Christian Ciancio

Abstract

In the WHO European Region, COVID-19 surveillance was implemented 27 January 2020. We detail the first European cases. As at 21 February, nine European countries reported 47 cases. Among 38 cases studied, 21 were linked to two clusters in Germany and France, 14 were infected in China. Median case age was 42 years; 25 were male. Late detection of the clusters' index cases delayed isolation of further local cases. As at 5 March, there were 4,250 cases.

Keywords: COVID-19; Novel coronavirus; SARS; SARS-COV-2; coronavirus disease 2019.

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure
Figure
Epidemic curve of reported COVID-19 cases by date of symptom onset, or date of notification, WHO European Region, as at 21 February 2020 (n = 38)a,b

References

    1. Wuhan City Health Committee (WCHC). Wuhan Municipal Health and Health Commission's briefing on the current pneumonia epidemic situation in our city 2019. [Accessed 14 Jan 2020]. Available from:
    1. European Centre for Disease Prevention and Control (ECDC). Rapid Risk Assessment: Outbreak of acute respiratory syndrome associated with a novel coronavirus, Wuhan, China; first update – 22 January 2020. Stockholm: ECDC; 2020. Available from:
    1. European Centre for Disease Prevention and Control (ECDC). Outbreak of acute respiratory syndrome associated with a novel coronavirus, China: first local transmission in the EU/EEA – third update. 31 January 2020. Stockholm: ECDC; 2020. Available from:
    1. European Centre for Disease Prevention and Control (ECDC). Geographical distribution of 2019-nCov cases globally 2020 – 02 February 2020. Stockholm: ECDC. [Accessed 12 Feb 2020]. Available from:
    1. World Health Organization Regional Office for Europe. ((WHO/Europe). Countries 2020. Copenhagen: WHO/Europe. [Accessed 12 Feb 2020]. Available from:
    1. European Centre for Disease Prevention and Control (ECDC). 2019 novel coronavirus (nCoV) disease data Reporting Protocol Version 1, 27 Jan 2020.
    1. World Health Organization (WHO). Coronavirus disease (COVID-19) technical guidance: Surveillance and case definitions. Geneva: WHO; 2020. Available from:
    1. European Centre for Disease Prevention and Control (ECDC). European surveillance for human infection with novel coronavirus (2019-nCoV) 2020. Stockholm: ECDC. [Accessed 30 Jan 2020]. Available from:
    1. Reusken CBEM, Broberg EK, Haagmans B, Meijer A, Corman VM, Papa A, et al. On Behalf Of Evd-LabNet And Erli-Net Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020. Euro Surveill. 2020;25(6):2000082. 10.2807/1560-7917.ES.2020.25.6.2000082
    1. Bernard Stoecklin S, Rolland P, Silue Y, Mailles A, Campese C, Simondon A, et al. Investigation Team First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020. Euro Surveill. 2020;25(6):2000094. 10.2807/1560-7917.ES.2020.25.6.2000094
    1. Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020. Euro Surveill. 2020;25(5):2000062. 10.2807/1560-7917.ES.2020.25.5.2000062
    1. Bayerische Gesundheitsministerium. Lungenentzündungen durch ein neuartiges Coronavirus. [Pneumonia caused by a new type of coronavirus]. Munich: Bayerische Gesundheitsministerium; 2020. German. [Accessed 12 Feb 2020]. Available from:
    1. Santé publique France. Epidémie de coronavirus (2019-nCov) au départ de Wuhan, Chine. [Coronavirus epidemic (2019-nCov) originating from Wuhan, China]. Paris: Santé publique France; 2020. French. [Accessed 12 Feb 2020]. Available from:
    1. Department of Health and Social Care. Chief Medical Officer for England announces 4 further coronavirus cases. London: Department of Health and Social Care; 2020. [Accessed 22 Feb 2020]. Available from:
    1. Santé publique France. COVID-19: situation des cas groupés dans les Alpes, France. [COVID-19: Situation on cluster of cases in the Alps, France]. Paris: Santé publique France; 2020. French. Available from:
    1. European Commission. Commission Implementing Decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions. 2018;(2119):1-74. Available from:
    1. Corman V, Bleicker T, Brünink S, Drosten C, Landt O, Koopmans M, et al. Diagnostic detection of Wuhan coronavirus 2019 by real-time RT-PCR – Protocol and preliminary evaluation as of Jan 13, 2020. [Accessed 17 Jan 2020]. Geneva: WHO; Jan 2020. Available from:
    1. European Centre for Disease Prevention and Control (ECDC). Outbreak of novel coronavirus disease 2019 (COVID19): situation in Italy – 23 February 2020. Stockholm: ECDC; 2020. Available from:
    1. World Health Organization Regional Office for Europe (WHO/Europe). COVID-19 situation in the WHO European Region. Copenhagen: WHO/Europe. [Accessed 5 Mar 2020]. Available from:
    1. Lebensmittelsicherheit BLfGu, Robert Koch Institute Beschreibung des bisherigen Ausbruchsgeschehens mit dem neuartigen Coronavirus SARS-CoV-2 in Deutschland (Stand: 12. Februar 2020). [Description of the novel coronavirus SARS-CoV-2 outbreak in Germany (as at 12 February 2020)]. German. Epidemiologisches Bulletin. 2020;7:3-4.
    1. World Health Organization (WHO). Global Surveillance for COVID-19 disease caused by human infection with novel coronavirus (COVID-19). Geneva: WHO; 2020. [Accessed 4 Mar 2020]. Available from:
    1. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020. China: Chinese Center for Disease Control and Prevention; 2020. [Accessed 18 Feb 2020]. Available from:
    1. The Novel Coronavirus Pneumonia Emergency Response Epidemiology T. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020. China CDC Weekly. 2020;2(8):113-22.

Source: PubMed

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