Effect of statins on skeletal muscle: exercise, myopathy, and muscle outcomes
Beth A Parker, Paul D Thompson, Beth A Parker, Paul D Thompson
Abstract
Statins are effective in reducing low-density lipoprotein cholesterol and cardiac events but can produce muscle side effects. We have hypothesized that statin-related muscle complaints are exacerbated by exercise and influenced by factors including mitochondrial dysfunction, membrane disruption, and/or calcium handling. The interaction between statins, exercise, and muscle symptoms may be more effectively diagnosed and treated as rigorous scientific studies accumulate.
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Source: PubMed