COVID-19 with acute cholecystitis: a case report

Mingliang Ying, Bin Lu, Jiangfeng Pan, Guanghong Lu, Shaobin Zhou, Dingjun Wang, Lu Li, Junkang Shen, Jiner Shu, From the COVID-19 Investigating and Research Team, Mingliang Ying, Bin Lu, Jiangfeng Pan, Guanghong Lu, Shaobin Zhou, Dingjun Wang, Lu Li, Junkang Shen, Jiner Shu, From the COVID-19 Investigating and Research Team

Abstract

Background: The 2019 novel coronavirus (COVID-19) presents a major threat to public health and has rapidly spread worldwide since the outbreak in Wuhan, Hubei Province, China in 2019. To date, there have been few reports of the varying degrees of illness caused by the COVID-19.

Case presentation: A case of 68-year-old female with COVID-19 pneumonia who had constant pain in the right upper quadrant of her abdomen during her hospitalization that was finally diagnosed as acute cholecystitis. Ultrasound-guided percutaneous transhepatic gallbladder drainage (PTGD) was performed, and the real-time fluorescence polymerase chain reaction (RT-PCR) COVID-19 nucleic acid assay of the bile was found to be negative. PTGD, antibacterial and anti-virus combined with interferon inhalation treatment were successful.

Conclusion: The time course of chest CT findings is typical for COVID-19 pneumonia. PTGD is useful for acute cholecystitis in COVID-19 patients. Acute cholecystitis is likely to be caused by COVID-19 .

Keywords: 2019-nCoV; Acute cholecystitis; COVID-19; Computed tomography; Pneumonia.

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Chest and abdominal plain CT scans in a 68-year-old woman with COVID-19 pneumonia and acute csholecystitis. a, b. Transverse chest CT scan obtained on the first day after admission shows multifocal peripheral GGOs in the dorsal (a) and posterior basal (b) segments of the right lower lobe. c, d. Follow-up chest CT scan obtained on day 3 after admission shows progression of the GGOs. e, f. Follow-up chest CT scan obtained on day 13 after admission shows that the GGOs were partly resolved in the dorsal segment of the right lower lobe (e) and completely resolved in the posterior basal segment of the right lower lobe (f). g. Coronal MPR of the plain abdominal CT obtained on day 11 shows a distended gallbladder, hyperplasia of the gallbladder wall, biliary sludge (arrow), and no gallstones in the gallbladder. h. Coronal MPR of the plain abdominal CT obtained on day 13 shows shrinkage of the gallbladder or its change in shape, a high-density drainage tube and a little bleeding in the gallbladder. CT = computer tomography, GGOs = ground-glass opacities, MPR = multiplanar reconstruction

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Source: PubMed

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