Rotavirus and severe childhood diarrhea

Umesh D Parashar, Christopher J Gibson, Joseph S Bresee, Roger I Glass, Umesh D Parashar, Christopher J Gibson, Joseph S Bresee, Roger I Glass

Abstract

Studies published between 1986 and 1999 indicated that rotavirus causes approximately 22% (range 17%-28%) of childhood diarrhea hospitalizations. From 2000 to 2004, this proportion increased to 39% (range 29%-45%). Application of this proportion to the recent World Health Organization estimates of diarrhea-related childhood deaths gave an estimated 611,000 (range 454,000-705,000) rotavirus-related deaths.

Figures

Figure 1
Figure 1
Percentage of severe diarrhea cases attributable to rotavirus for countries in different World Bank income groups, by per capita gross national product (GNP), for studies published in 1986–1999 and 2000–2004. GNP is in US dollars. Upper line, trend for 2000–2004; lower line, trend for 1986–1999.
Figure 2
Figure 2
Estimated global distribution of rotavirus-related deaths. Each dot represents 1,000 rotavirus-related deaths.

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