Definition and application of neuropsychological test battery to evaluate postoperative cognitive dysfunction

Lívia Stocco Sanches Valentin, Ricardo Pietrobon, Wagner de Aguiar Junior, Ruth Pinto Camarão Rios, Mariane Galzerano Stahlberg, Iolanda Valois Galvão de Menezes, Kátia Osternack-Pinto, Maria José Carvalho Carmona, Lívia Stocco Sanches Valentin, Ricardo Pietrobon, Wagner de Aguiar Junior, Ruth Pinto Camarão Rios, Mariane Galzerano Stahlberg, Iolanda Valois Galvão de Menezes, Kátia Osternack-Pinto, Maria José Carvalho Carmona

Abstract

Objective: To investigate the adequacy of the neuropsychological test battery proposed by the International Study of Postoperative Cognitive Dysfunction to evaluate this disorder in Brazilian elderly patients undergoing surgery under general anesthesia.

Methods: A neuropsychological assessment was made in patients undergoing non-cardiac surgery under general anesthesia, aged over 65 years, literate, with no history of psychiatric or neurological problems and score on the Mini Mental State Examination at or above the cutoff point for the Brazilian population (>18 or >23) according to the schooling level of the subject. Eighty patients were evaluated by a trained team of neuropsychologists up to 24 hours before elective surgery.

Results: Among the patients evaluated, one was excluded due to score below the cutoff point in the Mini Mental State Examination and two did not complete the test battery, thus remaining 77 patients in the study. The mean age was 69±7.5 years, and 62.34% of the subjects had ±4 years of study. The subjects had significantly lower averages than expected (p<0.001) for normative tables on neuropsychological tests.

Conclusion: The study demonstrated the applicability of the instruments in the Brazilian elderly and low schooling level population, but suggested the need to determine cutoff points appropriate for these individuals, ensuring the correct interpretation of results. This battery is relevant to postoperative follow-up evaluations, favoring the diagnosis of postoperative cognitive dysfunction in patients undergoing different types of surgery and anesthetic techniques.

Conflict of interest statement

Conflict of interest: none.

Figures

Figure 1. Composition of the sample according…
Figure 1. Composition of the sample according to inclusion criteria
Figura 1. Composição da amostra conforme critérios…
Figura 1. Composição da amostra conforme critérios de inclusão

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