School Support as Structural HIV Prevention for Adolescent Orphans in Kenya
調査の概要
詳細な説明
This study examines the impact of school support as a structural intervention, tested among adolescent orphans in Siaya District, Nyanza Province, Kenya.
Aims for the proposed study are: 1) To experimentally test whether providing comprehensive school support to Kenyan orphaned boys and girls will reduce school dropout, reduce sexual risk behaviors, and prevent HIV/HSV-2 infection; 2) To conduct a process evaluation of the implementation of the program; and 3) To conduct comparative cost effectiveness analyses, specifying the intervention's cost and return on investment as evidenced by cost per unit improvement in the primary outcomes of school enrollment, delay of sexual debut and prevention of risk behaviors and HIV/HSV-2 infection, as well as by gains in health-related quality of life.
研究の種類
入学 (実際)
段階
- フェーズ2
連絡先と場所
参加基準
適格基準
就学可能な年齢
- 子
- 大人
- 高齢者
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- Orphan (one or both parents deceased)
- In Grade 7 or 8 in a primary school participating in the study
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：防止
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：School Support Group
School Support Intervention
|
Comprehensive school support is provided that includes payment of school fees, school uniform, and a nurse researcher who monitors attendance and addresses problems that may lead to school absence and dropout.
|
|
介入なし：Control
No school support
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
時間枠 |
|---|---|
|
Dropped out of school
時間枠：From date of randomization until drop out from school, up to 3 years
|
From date of randomization until drop out from school, up to 3 years
|
|
Change from baseline in ever had sexual intercourse at 1 year
時間枠：Baseline and 1 year
|
Baseline and 1 year
|
|
Change from baseline in ever had sexual intercourse at 2 years
時間枠：Baseline and 2 years
|
Baseline and 2 years
|
|
Change from baseline in ever had sexual intercourse at 3 years
時間枠：Baseline and 3 years
|
Baseline and 3 years
|
|
HIV Incidence
時間枠：3 years
|
3 years
|
|
HSV-2 Incidence
時間枠：3 years
|
3 years
|
二次結果の測定
結果測定 |
時間枠 |
|---|---|
|
Ever married or ever pregnant
時間枠：From date of randomization until marriage or preganancy, up to 3 years
|
From date of randomization until marriage or preganancy, up to 3 years
|
|
Health-related quality of life
時間枠：Baseline and 1 year
|
Baseline and 1 year
|
|
Health-related quality of life
時間枠：Baseline and 2 years
|
Baseline and 2 years
|
|
Health-related quality of life
時間枠：Baseline and 3 years
|
Baseline and 3 years
|
協力者と研究者
協力者
捜査官
- 主任研究者：Hyunsan Cho, Ph.D.、Pacific Institute for Research and Evaluation
出版物と役立つリンク
一般刊行物
- Cho H, Mbai I, Luseno WK, Hobbs M, Halpern C, Hallfors DD. School Support as Structural HIV Prevention for Adolescent Orphans in Western Kenya. J Adolesc Health. 2018 Jan;62(1):44-51. doi: 10.1016/j.jadohealth.2017.07.015. Epub 2017 Nov 6.
- Hallfors DD, Cho H, Mbai II, Millimo BW, Atieno C, Okumu D, Luseno WK, Hartman S, Halpern CT, Hobbs MM. Disclosure of HSV-2 serological test results in the context of an adolescent HIV prevention trial in Kenya. Sex Transm Infect. 2015 Sep;91(6):395-400. doi: 10.1136/sextrans-2015-052025. Epub 2015 Jul 2.
- Cho H, Luseno W, Halpern C, Zhang L, Mbai I, Milimo B, Hallfors DD. Discordance of HIV and HSV-2 biomarkers and self-reported sexual behaviour among orphan adolescents in Western Kenya. Sex Transm Infect. 2015 Jun;91(4):260-5. doi: 10.1136/sextrans-2014-051720. Epub 2014 Nov 6.
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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