スナック、笑顔、味の好み
2026年6月4日 更新者:Temple University
甘いものを好む傾向がシフトダウンし、間食時の砂糖摂取量が増加
この調査研究は、対照群と比較して甘味の低いスナックを繰り返し摂取した後に、子供の低糖スナックの受け入れ、甘味と塩味の最も好ましいレベル、および添加された砂糖の食事摂取量が変化するかどうかを判断することを目的としています。
調査の概要
詳細な説明
これは、子どもとその母親を対象とした縦断的、ランダム化された被験者内および被験者間研究であり、甘さの低いスナックと母親による歯の健康と栄養に関する教育的レッスン(介入群)を子どもが繰り返し摂取することが、子どもの低糖質の受け入れに影響を与えるかどうかを判定するものである。コントロールグループと比較した場合、スナック、最も好ましい甘味と塩味のレベル、および添加された砂糖の食事摂取量。
研究の種類
介入
入学 (実際)
172
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
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Pennsylvania
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Philadelphia、Pennsylvania、アメリカ、19104
- Monell Chemical Senses Center
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Philadelphia、Pennsylvania、アメリカ、19140
- Temple University
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参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
3年~6年 (子)
健康ボランティアの受け入れ
はい
説明
包含基準:
- 英語を話す18歳以上の母親
- 母親は対象となる子供の養育に対して主な責任を負う
- 母親は対象となる子供に食事を与える主な責任がある
- 母親は家族のために食べ物を買う責任がある
- 母親は、研究期間中、対象となる子供の面前で糖分を多く含む食べ物や飲み物を摂取することを喜んで控えなければなりません。
除外基準:
- 子供が全日制の保育園または学校に通っている
- 子供は現在特別な食事をとっている(例: 体重管理プログラム)
- 子供には重度の食物アレルギーがあります(例: グルテン、ピーナッツ)
- 子供には、成長や食事に影響を与えることが知られている病状がある(例: 糖尿病、嚢胞性線維症)
- 母親は現在喫煙者です
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:基礎科学
- 割り当て:ランダム化
- 介入モデル:並列代入
- マスキング:トリプル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的:ロースイート
介入グループの子どもたちには、砂糖と甘味料の添加量が少ないおやつが毎日提供され、母親は、「甘いもの」への曝露と砂糖の摂取量を減らすという目標をサポートする、歯のケア、食品ラベルの読み方、栄養に関する教育レッスンを受けます。
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実験グループの子供たちは甘さ控えめのスナックを繰り返し与えられ、母親は歯のケア、食品ラベルの読み方、分量、栄養に関する教育レッスンを受けます。
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偽コンパレータ:レギュラースイート
通常の甘い対照群の子どもたちには、この年齢の子どもたちに与えられる一般的なスナックが提供され、母親には一食の量、身体活動、睡眠、スクリーンタイム、そして試験終了時には歯科ケアについての教育レッスンが与えられる。
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偽の比較対象の子供たちは典型的なおやつを与えられ、母親は分量、身体活動、睡眠、スクリーンタイムについての教育レッスンを受けます。
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Children's Dietary Intake of Energy From Added Sugar (Tsp/d)
時間枠:From T1 (baseline Temple visit at start of intervention) to T2 (Month 2, mid-trial), T3 (Month 4, end of intervention) and T4 (Month 5, which is 1 month post-intervention follow-up)
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Children's dietary intake of added sugar (tsp/d) was determined from Automated Self-Administered Recall System (ASA24) at baseline, mid-trial, and end of trial.
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From T1 (baseline Temple visit at start of intervention) to T2 (Month 2, mid-trial), T3 (Month 4, end of intervention) and T4 (Month 5, which is 1 month post-intervention follow-up)
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Caregiver's Dietary Intake of Energy From Added Sugar (Tsp/d)
時間枠:At T1 (baseline Temple visit at start of intervention) to T2 (Month 2, mid-trial), T3 (Month 4, end of intervention) and T4 (Month 5, which is 1 month post-intervention follow-up)
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Caregivers' dietary intake of added sugar (tsp/d) was determined from Automated Self-Administered Recall System (ASA24) at baseline, mid-trial, and end of trial.
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At T1 (baseline Temple visit at start of intervention) to T2 (Month 2, mid-trial), T3 (Month 4, end of intervention) and T4 (Month 5, which is 1 month post-intervention follow-up)
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Children's Liking of Snacks Low in Sweetness (SET 1 FOODS)
時間枠:At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention). Liking assessments of Set 1 and Set 2 foods were performed at separate laboratory visits.
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Children's indicated liking of two sets of lower sweetness intervention snack foods (Set 1: Strawberry-banana yogurt, apple slices; Set 2: hummus and baby carrots), assessed on separate occasions.
Using hedonic face scales, children indicated their like or dislike for each food.
Liking data were not obtained during the COVID-19 lockdown.
Set 1 foods were discontinued following the lockdown in a modified version of the protocol moved from in person visits to remote assessments.
As such, outcome analyses of children's liking of snacks low in sweetness are reported on complete cases (Set 1 foods: n=40 children; Set 2 foods: n=54 children).
This analysis shows the count of and percentage of children who liked SET 1 STRAWBERRY-BANANA YOGURT AND APPLE SLICES at the end of the intervention.
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At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention). Liking assessments of Set 1 and Set 2 foods were performed at separate laboratory visits.
|
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Children's Liking of Snacks Low in Sweetness (SET 2 FOODS)
時間枠:At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention). Liking assessments of Set 1 and Set 2 foods were performed at separate laboratory visits.
|
Children's indicated liking of two sets of lower sweetness intervention snack foods (Set 1: Strawberry-banana yogurt, apple slices; Set 2: hummus and baby carrots), assessed on separate occasions.
Using hedonic face scales, children indicated their like or dislike for each food.
Liking data were not obtained during the COVID-19 lockdown.
Set 1 foods were discontinued following the lockdown in a modified version of the protocol moved from in person visits to remote assessments.
As such, outcome analyses of children's liking of snacks low in sweetness are reported on complete cases (Set 1 foods: n=40 children; Set 2 foods: n=54 children).
This analysis shows the number and percentage of children who liked SET 2 HUMMUS AND BABY CARROTS at the end of the intervention.
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At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention). Liking assessments of Set 1 and Set 2 foods were performed at separate laboratory visits.
|
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Children's Intake (g) of Snacks Low in Sweetness (SET 1 FOODS)
時間枠:At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention)
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Children's intake of novel snacks in grams using weighed intake methods; higher intake and consummatory responses indicate greater acceptance.
Children's ad libitum intake of two sets of lower sweetness intervention snack foods was assessed on separate occasion (Set 1: Strawberry-banana yogurt, apple slices; Set 2: hummus and baby carrots), a protocol that directly followed assessment of liking.
Weighed intakes were used to measure children's intake of each food in grams.
Intake data were not obtained during the COVID-19 lockdown.
Set 1 foods were discontinued following the lockdown in a modified version of the protocol moved from in person visits to remote assessments.
As such, outcome analyses of children's liking of snacks low in sweetness are reported on complete cases (Set 1 foods: n=40 children; Set 2 foods: n=54 children).
This analysis presents INTAKE in GRAMS of SET 1 STRAWBERRY-BANANA YOGURT AND APPLE SLICES at the END OF TRIAL.
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At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention)
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Children's Intake (g) of Snacks Low in Sweetness (SET 2 FOODS)
時間枠:At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention)
|
Children's intake of novel snacks in grams using weighed intake methods; higher intake and consummatory responses indicate greater acceptance.
Children's ad libitum intake of two sets of lower sweetness intervention snack foods was assessed on separate occasion (Set 1: Strawberry-banana yogurt, apple slices; Set 2: hummus and baby carrots), a protocol that directly followed assessment of liking.
Weighed intakes were used to measure children's intake of each food in grams.
Intake data were not obtained during the COVID-19 lockdown.
Set 1 foods were discontinued following the lockdown in a modified version of the protocol moved from in person visits to remote assessments.
As such, outcome analyses of children's liking of snacks low in sweetness are reported on complete cases (Set 1 foods: n=40 children; Set 2 foods: n=54 children).
This analysis presents INTAKE in GRAMS of SET 2 HUMMUS and BABY CARROTS at the END OF TRIAL.
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At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention)
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Children's Body Mass Index Z-scores (BMIz)
時間枠:At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention)
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Children's height was measured in cm and weight in kg; these measures were used to calculate child BMI (kg/m2).
Child BMI z-scores were calculated with CDC 2000 growth charts using the LMS method, which standardizes a child's BMI relative to a reference population of U.S. children of the same age and sex.
The BMI z-score indicates how many standard deviations the child's BMI is above or below the CDC age- and sex-specific average, with higher positive values indicating higher relative body size compared to children of the same age and sex in the CDC reference population.
This analysis compares child BMIz by arm at the END OF TRIAL.
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At T1 (baseline visit at start of intervention) and T3 (4 month= end of intervention)
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Children's Stable Isotope Biomarker of Added Sugar Intake
時間枠:From T1 (baseline Temple visit at start of intervention) to T3 (4 month visit=end of intervention)
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Carbon stable isotopes were assessed using ratio mass spectrometry methods using hair samples collected at the start (T0) and end of 4-month intervention (T4).
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From T1 (baseline Temple visit at start of intervention) to T3 (4 month visit=end of intervention)
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Monitoring of Individual Differences in Parenting Feeding Styles
時間枠:T1 (baseline Temple visit at start of intervention)
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Mothers will complete the 19-item Caregivers Feeding Styles Questionnaire [CFSQ].
Each item is scored from 1 (never) to 5 (always).
Mean item scores were used to assess parental demandingness (12 items) and responsiveness (7 items), with a possible range of 1 to 5 for each scale where higher scores indicate higher levels of the construct.
This measure was collected and checked at baseline to ensure that there were no differences by group/arm.
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T1 (baseline Temple visit at start of intervention)
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Monitoring of Individual Differences in Children's Appetitive Drive
時間枠:T1 (baseline Temple visit at start of intervention)
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Mothers will complete the 26-item Children's Eating Behavior Questionnaire [CEBQ].
Each item is scored from 1 (never) to 5 (always) and are averaged and categorized into aspects of child eating (e.g., enjoyment of food, food responsiveness, satiety responsiveness, emotional overeating; emotional undereating, food fussiness); higher numbers reflect more of the behavior.
This measure was collected and checked at baseline to ensure that there were no differences by group/arm.
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T1 (baseline Temple visit at start of intervention)
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Monitoring of Individual Differences in Children's Behavioral Activation
時間枠:T1 (baseline Temple visit at start of intervention)
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Children's behavioral activation was measured using the Behavioral Activation Scale, a 20-item self-report questionnaire assessing children's sensitivity to reward and approach motivation across 3 subscales: drive (4 items), fun seeking (4 items), and reward responsiveness (5 items).
Each question is answered using a 4-point Likert-type scale, with possible scores ranging from 1 (not true) -4 (very true).
Scores for each of the three subscales are calculated as the sum of all items on the subscale, with higher scores indicating higher levels of the construct.
Possible scores ranges for subscales are as follows: drive (4-16); fun seeking (4-16), and reward responsiveness (5-20).
This measure was collected and checked at baseline to ensure that there were no differences by group/arm.
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T1 (baseline Temple visit at start of intervention)
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Monitoring of Individual Differences in Mothers' Palatable Eating Motivation
時間枠:T1 (baseline Temple visit at start of intervention)
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Mothers will complete the 19-item Palatable Eating Motive Scales (PEMS) questionnaire; each item is scored from 1 (almost never/never exhibits behavior) to 5 (almost always/always exhibits behavior).
Scores are averaged and categorized to reflect motives for intake of palatable foods (e.g., to socialize, cope, fit in or conform, for reward enhancement); higher numbers reflect more of the motivation.This measure was collected and checked at baseline to ensure that there were no differences by group/arm.
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T1 (baseline Temple visit at start of intervention)
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その他の成果指標
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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母子二兄弟間の追加糖摂取量の毛髪バイオマーカーの一致
時間枠:時点0(介入開始時のベースライン寺院訪問)とT4(4か月の訪問=介入終了)における毛髪バイオマーカーレベルの関係
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追加された砂糖摂取量の推定値は、4 か月の介入期間の開始時 (T0) と終了時 (T4)、4 か月の介入期間の終了時 (T4) に母子から採取された毛髪サンプルの安定同位体比質量分析法によって決定されます。母子二者間の一致を判断する
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時点0(介入開始時のベースライン寺院訪問)とT4(4か月の訪問=介入終了)における毛髪バイオマーカーレベルの関係
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
スポンサー
協力者
捜査官
- 主任研究者:Julia Mennella, PhD、Monell Chemical Senses Center
- 主任研究者:Jennifer O Fisher, PhD、Temple University
出版物と役立つリンク
研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。
一般刊行物
- Wardle J, Guthrie CA, Sanderson S, Rapoport L. Development of the Children's Eating Behaviour Questionnaire. J Child Psychol Psychiatry. 2001 Oct;42(7):963-70. doi: 10.1111/1469-7610.00792.
- Mennella JA, Lukasewycz LD, Griffith JW, Beauchamp GK. Evaluation of the Monell forced-choice, paired-comparison tracking procedure for determining sweet taste preferences across the lifespan. Chem Senses. 2011 May;36(4):345-55. doi: 10.1093/chemse/bjq134. Epub 2011 Jan 12.
- Nash SH, Kristal AR, Hopkins SE, Boyer BB, O'Brien DM. Stable isotope models of sugar intake using hair, red blood cells, and plasma, but not fasting plasma glucose, predict sugar intake in a Yup'ik study population. J Nutr. 2014 Jan;144(1):75-80. doi: 10.3945/jn.113.182113. Epub 2013 Nov 6.
- Mennella JA, Finkbeiner S, Lipchock SV, Hwang LD, Reed DR. Preferences for salty and sweet tastes are elevated and related to each other during childhood. PLoS One. 2014 Mar 17;9(3):e92201. doi: 10.1371/journal.pone.0092201. eCollection 2014.
- Vandeweghe L, Verbeken S, Moens E, Vervoort L, Braet C. Strategies to improve the Willingness to Taste: The moderating role of children's Reward Sensitivity. Appetite. 2016 Aug 1;103:344-352. doi: 10.1016/j.appet.2016.04.017. Epub 2016 Apr 19.
- Hughes SO, Power TG, Orlet Fisher J, Mueller S, Nicklas TA. Revisiting a neglected construct: parenting styles in a child-feeding context. Appetite. 2005 Feb;44(1):83-92. doi: 10.1016/j.appet.2004.08.007. Epub 2004 Nov 13.
- Sharafi M, Rawal S, Fernandez ML, Huedo-Medina TB, Duffy VB. Taste phenotype associates with cardiovascular disease risk factors via diet quality in multivariate modeling. Physiol Behav. 2018 Oct 1;194:103-112. doi: 10.1016/j.physbeh.2018.05.005. Epub 2018 May 8.
- Martignon S, Gonzalez MC, Tellez M, Guzman A, Quintero IK, Saenz V, Martinez M, Mora A, Espinosa LF, Castiblanco GA. Schoolchildren's tooth brushing characteristics and oral hygiene habits assessed with video-recorded sessions at school and a questionnaire. Acta Odontol Latinoam. 2012;25(2):163-70.
- Mennella JA, Pepino MY, Lehmann-Castor SM, Yourshaw LM. Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression. Addiction. 2010 Apr;105(4):666-75. doi: 10.1111/j.1360-0443.2009.02865.x. Epub 2010 Feb 9.
- Mennella JA, Coffman DL, Merchan MT, Croce CM, Smethers AD, Fisher JO. Exposure to low-sweet snacks and caregiver nutritional and dental health education lowered children's added sugar intake: a randomized controlled trial. Am J Clin Nutr. 2026 Mar 13:101272. doi: 10.1016/j.ajcnut.2026.101272. Online ahead of print.
- Smethers AD, Fisher JO, Carney EM, Coffman DL, Mennella JA. Carbon stable isotope values in hair are associated with added sugar intake in adults but not young children: a cross-sectional study. Am J Clin Nutr. 2025 Apr;121(4):900-909. doi: 10.1016/j.ajcnut.2025.02.013. Epub 2025 Feb 18.
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2018年10月9日
一次修了 (実際)
2024年10月18日
研究の完了 (実際)
2024年10月18日
試験登録日
最初に提出
2018年5月29日
QC基準を満たした最初の提出物
2018年8月13日
最初の投稿 (実際)
2018年8月15日
学習記録の更新
投稿された最後の更新 (実際)
2026年6月30日
QC基準を満たした最後の更新が送信されました
2026年6月4日
最終確認日
2026年6月1日
詳しくは
本研究に関する用語
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
はい
IPD プランの説明
dbGAP
IPD 共有時間枠
2022年から1年間
IPD 共有アクセス基準
開発される
IPD 共有サポート情報タイプ
- STUDY_PROTOCOL
- SAP
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
米国で製造され、米国から輸出された製品。
いいえ
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