PNF Versus Cryotherapy in Delayed Onset Muscle Soreness
2026年6月13日 更新者：Sara Perpiñá、Universidad Pontificia de Salamanca
Efficacy of Proprioceptive Neuromuscular Facilitation Versus Cryotherapy and Placebo on Delayed Onset Muscle Soreness: A Randomized Pilot Clinical Trial
This randomized, double-blind, single-center pilot clinical trial evaluated three interventions for delayed onset muscle soreness in the hamstring muscles.
Twenty-nine untrained adults were included. Delayed onset muscle soreness was induced using two eccentric hamstring exercises. Participants were then assigned to one of three groups: proprioceptive neuromuscular facilitation, local cryotherapy, or placebo consisting of water with sugar.
The main outcome was pressure pain threshold in the hamstring muscles. Other outcomes included knee range of motion, hamstring strength, pain intensity, perceived exertion, and blood lactate levels. Measurements were taken before the eccentric exercise, 24 hours after exercise before treatment, immediately after treatment, and 48 hours after exercise.
調査の概要
状態
完了
研究の種類
介入
入学 (実際)
29
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
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Madrid
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Madrid、Madrid、スペイン、28015
- Clínica Universitaria Salus Infirmorum, Universidad Pontificia de Salamanca
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参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
- Adults aged between 18 and 45 years.
- Participants who did not usually perform physical exercise or whose exercise was not focused on the lower limbs.
- Participants who had previously experienced delayed onset muscle soreness and were familiar with its effects.
Exclusion Criteria:
- Musculoskeletal injury of the lower limb.
- Pregnancy.
- Diabetes.
- Cardiovascular problems.
- History of cancer.
- Autoimmune diseases, including Raynaud disease or rheumatoid arthritis.
- Sensory disorders.
- Skin disorders.
- Skin conditions.
- Peripheral venous or lymphatic vascular insufficiency.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：独身
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的：Proprioceptive Neuromuscular Facilitation
Participants received a proprioceptive neuromuscular facilitation intervention targeting the hamstring muscles 24 hours after eccentric exercise-induced delayed onset muscle soreness.
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A contract-relax-antagonist-contract proprioceptive neuromuscular facilitation technique was applied to the hamstring muscles.
The protocol included isometric hamstring contraction, rest, quadriceps contraction, and passive movement into a deeper hamstring stretch.
The protocol was repeated twice on each leg.
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実験的：Cryotherapy
Participants received local cryotherapy over the hamstring muscles 24 hours after eccentric exercise-induced delayed onset muscle soreness.
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Participants were placed in prone position and an ice pack was applied over the hamstring muscles for 20 minutes.
A thin cloth was placed between the ice pack and the skin to avoid direct contact.
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プラセボコンパレーター：water with sugar
Participants received a placebo intervention consisting of water with sugar 24 hours after eccentric exercise-induced delayed onset muscle soreness.
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Participants consumed 200 mL of water with 5 g of dissolved sugar after the eccentric exercise protocol.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Change in Pressure Pain Threshold in the Hamstring Muscles
時間枠：Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Pressure pain threshold was assessed using a pressure algometer over three points of maximum pain in the hamstring muscles.
Three measurements were taken and the mean value was calculated.
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Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Change in Active Knee Range of Motion
時間枠：Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Active knee flexion and extension range of motion were assessed using a manual goniometer.
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Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Change in Hamstring Muscle Strength
時間枠：Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Maximum hamstring strength was assessed using a handheld dynamometer.
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Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Change in Blood Lactate Concentration
時間枠：Before exercise, immediately after exercise, and 48 hours after exercise
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Blood lactate concentration was measured using a Lactate Edge device.
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Before exercise, immediately after exercise, and 48 hours after exercise
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Change in Pain Intensity
時間枠：Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Pain intensity was assessed using the 11-point Numeric Pain Rating Scale.
Scores range from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain.
Higher scores indicate greater pain intensity and therefore a worse outcome.
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Baseline, 24 hours after eccentric exercise before treatment, immediately after treatment, and 48 hours after eccentric exercise
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Perceived Exertion After Eccentric Exercise
時間枠：Immediately after eccentric exercise
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Perceived exertion was assessed using the Modified Borg Rating of Perceived Exertion Scale after completion of the eccentric exercise protocol.
Scores range from 0 to 10, where 0 indicates no exertion and 10 indicates maximal exertion.
Higher scores indicate greater perceived exertion and therefore a worse outcome.
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Immediately after eccentric exercise
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
捜査官
- 主任研究者：Sara Perpiña Martínez, PhD、Universidad Pontificia de Salamanca
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2025年1月1日
一次修了 (実際)
2025年4月26日
研究の完了 (実際)
2025年4月30日
試験登録日
最初に提出
2026年5月28日
QC基準を満たした最初の提出物
2026年5月28日
最初の投稿 (実際)
2026年6月3日
学習記録の更新
投稿された最後の更新 (実際)
2026年6月16日
QC基準を満たした最後の更新が送信されました
2026年6月13日
最終確認日
2026年6月1日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- UPSA-DOMS-2025
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
はい
IPD プランの説明
De-identified individual participant data related to the outcomes reported in the study may be shared upon reasonable request to the principal investigator.
Data will only be shared for academic and research purposes, after approval by the study team, and in accordance with applicable data protection regulations.
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米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
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