Local Factors in the Onset/Progression of Peri-implantitis: A Retrospective Study
With the increasing burden of peri-implantitis worldwide, interest in the management of this pathology has flourished. However, there is a lack of consensus in the search for a predictable therapy. Different therapeutic modalities have been advocated. Non-surgical therapy as a sole modality is often insufficient to resolve inflammation. Surgical interventions have demonstrated more favorable results. Among these, evidence supported the application of resective, reconstructive or combined approaches to limit progressive bone loss and achieve soft tissue health. However, to date, the most appropriate modality is unknown and the decision-making process derives from the understanding gained in the management of periodontitis.
A very relevant aspect of peri-implantitis is that the prevalence tends to be higher at the patient level than at the implant level. This indicates that it is a pathology in which there are localized factors that may contribute to the onset and/or perpetuation of the pathology. Some of the factors that have been demonstrated in the literature point to the characteristics of the peri-implant soft tissues, as well as the position of the dental implants. However, the role of each local factor in the predisposition or protection of peri-implant disease or health is still largely unknown. The objective of this study is therefore to evaluate, in partially edentulous patients with multiple implants, the localized factors associated with peri-implantitis.
調査の概要
詳細な説明
Variables to explore:
Patient-related variables:
- Periodontal health (health, pathology)
- Periodontal status classification (stage, grade)
- Smoker (S, NS, FS)
- Compliance (NC, C, CE)
- Age (y)
- Time since implants (y)
- Pathology (DM, CVD, OP, other)
- Medication
- Anticoagulant (y/n)
- Plaque control (<20%, >20%, >50%)
Clinical variables:
- Keratinized mucosa (narrow, wide, lack)
- Vestibule (Deep ≥4mm, shallow <4mm, lack)
- Number of implants supporting the prosthesis (n)
- Implant location in the fixed prosthesis (mesial, distal, medial)
- Interproximal access with a 0.5mm brush between implants (IP-i)
- Interproximal access with a 0.5mm brush between implants implant-tooth (IP-t)
- Prosthesis type (SC, FPD)
- Cemented or screw-retained (C, S)
- Ceramic to connection (Y/N)
- Prosthesis material (Zr, Cr-Co)
- Implant (NB, ST, TC, DT, BTI, other)
- Implant diameter (mm)
- Implant length (mm)
- Position (M, PM, A, a, pm, m)
Radiographic variables:
- Distance between implants (m-d)
- Distance to adjacent tooth (m-d)
- Occlusal deviation towards buccal-lingual (b-l)
- Apico-coronal position with respect to adjacent tooth (a-c) with respect to LAC
- Apico-coronal position with respect to adjacent implant (a-c) with respect to coronal
- Inclination (implant deviation º) (m-d), (b-l) and º
- Defect configuration (Monje et al. 2019)
- Implant type (BL, TL)
- Transmucosal abutment (Y, N, short <2mm, long ≥2mm)
- Inadequate implant-prosthesis connection (Ill-fitting)
研究の種類
入学 (実際)
連絡先と場所
研究場所
-
-
-
Badajoz、スペイン、06011
- Centro de Implantologia Cirugia Oral y Maxilofacial
-
-
参加基準
適格基準
就学可能な年齢
- 大人
- 高齢者
健康ボランティアの受け入れ
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Partially edentulous patients
- Peri-implantitis and non-peri-implantitis implants
- Readable x-ray and clinical signs of inflammation/health
Exclusion Criteria:
- Complete edentulous patients
- Inconsistent definition of peri-implantitis
研究計画
研究はどのように設計されていますか?
デザインの詳細
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Peri-implantitis
時間枠:>12 months
|
Bone loss (≥3mm) occurring with clinical signs of inflammation
|
>12 months
|
協力者と研究者
捜査官
- スタディチェア:Alberto Monje Correa, DDS, MS, PhD、Cicom Monje
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- 18002909(B)
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
IPD プランの説明
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。