Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Managing Polycystic Ovarian Syndrome- Associated Reproductive Dysfunction Through Kefir Supplementation
調査の概要
状態
詳細な説明
The target population were females between the ages of 18 and 25 years who have the history of amenorrhea or delayed periods, unusual weight gain, cyst in their ovaries, hormonal imbalance or thyroid issue. Once consent is given, participants were then be randomly assigned to receive the prescribed intervention or act as a control.
(C0) Control group: Participants were only be subjected to use a regular calorie deficit diet plan (G1) Experimental group: Participants were advised to take water 250ml of water kefir per day in their mid-morning snack time for 2 months.
At baseline, nutritional assessment based on weight and height, BMI, waist circumference, blood pressure, fasting blood glucose, lipid panels (HDL, LDL, total cholesterol, triglycerides), FHS Levels, LH levels, TSH levels was done after 8 weeks of intervention.
研究の種類
入学 (実際)
段階
- 適用できない
連絡先と場所
研究場所
-
-
-
Lahore、パキスタン
- The University of Lahore
-
-
参加基準
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
説明
Inclusion Criteria:
- Females of age 18-25 will be selected.
- Females suffering from amenorrhea or cycle longer then 35days were selected.
- Females with PCOS were selected.
- Females with BMI 18.5-29.9 were selected in this research.
- Females with thyroid issues were selected.
Exclusion Criteria:
- Pregnant and breast-feeding females were not included.
- Those who smoke were not included.
- Those who consume alcohol were not included.
- Those suffering from endocrine diseases were not be included.
- Those taking lipid- lowering drugs or blood pressure regulating medications were not be included.
- Those taking antibiotics or medications related to PCOS treatment or vitamin-mineral or probiotics within 1 month prior to study inclusion.
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：支持療法
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
アクティブコンパレータ：Control Group
Calorie deficit diet plan
|
Participants were subjected to use a regular calorie deficit diet plan
|
|
実験的：Experimental Group
Diet plan + 250ml kefir water
|
Participants were advised to take water 250ml of water kefir per day in their mid-morning snack time for 2 months.
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Lipid Profile
時間枠：8 weeks
|
Blood lipid profile were obtained using fasting blood samples to determine serum total cholesterol, high-density lipoprotein cholesterol (HD L-C), low density lipoprotein cholesterol (LDL-C) and triglycerides.
|
8 weeks
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
FSH (follicle stimulating hormone)
時間枠：8 weeks
|
Blood test will be done to check the reproductive health
|
8 weeks
|
|
LH (luteinizing hormone)
時間枠：8 weeks
|
Blood test to check the secretion of luteinizing hormone and how it triggers ovulation and stimulate testosterone production.
|
8 weeks
|
その他の成果指標
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
TSH (Thyroid stimulating hormone test)
時間枠：8 weeks
|
Blood test were done to monitor the levels of TSH.
|
8 weeks
|
協力者と研究者
スポンサー
出版物と役立つリンク
便利なリンク
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- IRB-UOL-FAHS/761/2026
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
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