The Effect of Stress on the Residual Gastric Volume
The Effect of Stress on the Residual Gastric Volume in Older Adults Undergoing Staged-bilateral Total Knee Arthroplasty After Drinking Carbohydrate-containing Fluids: A Prospective Observational Study
In our institution, many patients undergo staged bilateral total knee arthroplasty at weekly intervals, and most of the patients are older adults with degenerative arthritis. As recommended, the older adult patients who undergoing total knee arthroplasty drink carbohydrate-containing fluid (400 ml) 2 hours prior to surgery. In this type of surgery, there are additional points to consider when applying the fasting guidelines. This is because, in addition to the factor of advanced age, which can affect gastric emptying time, the patient's physical, medical, and psychological conditions at the first and the second operation may be different. For example, the effect of the acute pain that occurs after the first total knee arthroplasty and subsequent opioids administered on gastric motility cannot be ignored. However, to date, there have been no studies examining the association of stress (emotional and surgical) and residual gastric volume of older adult patients with staged bilateral total knee arthroplasty and whether there is a difference according to the stage when carbohydrate-containing fluid is ingested.
In the present study, the investigators will evaluate the effect of emotional stress, surgical stress, pain, and the use of opioids on the residual gastric volume in older adults undergoing staged-bilateral total knee arthroplasty.
연구 개요
연구 유형
등록 (예상)
연락처 및 위치
연구 연락처
- 이름: Hyun-Jung Shin, MD., PhD.
- 전화번호: 82317877508
- 이메일: hjshin.anesth@gmail.com
연구 장소
-
-
Gyeonggi-do
-
Seongnam-si, Gyeonggi-do, 대한민국, 13620
- 모병
- Seoul National University Bundang Hospital
-
연락하다:
- Hyun-Jung Shin, MD., PhD.
- 이메일: hjshin.anesth@gmail.com
-
수석 연구원:
- Hyo-Seok Na, MD., PhD.
-
-
참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
샘플링 방법
연구 인구
설명
Inclusion Criteria:
- Patients scheduled for staged bilateral total knee arthroplasty aged ≥ 65
- American Society of Anesthesiologists physical status classification 1, 2, and 3
- Body mass index < 35 kg/cm2
- Patients administered carbohydrate-containing fluid 2 hours prior to surgery
Exclusion Criteria:
- Previous surgery of the upper gastrointestinal tract
- Achalasia
- Diabetes
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
코호트 및 개입
그룹/코호트 |
개입 / 치료 |
|---|---|
|
그룹 C
환자들은 수술 2시간 전에 탄수화물 음료를 마셨습니다.
|
탄수화물 체액 투여
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Level of stress hormone 1
기간: After induction of spinal anesthesia at first stage total knee arthroplasty/ an average 10 minutes
|
Stress hormone (interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α) measured after induction of spinal anesthesia
|
After induction of spinal anesthesia at first stage total knee arthroplasty/ an average 10 minutes
|
|
Level of stress hormone 2
기간: After induction of spinal anesthesia at second stage total knee arthroplasty/ an average 10 minutes
|
Stress hormone (interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α) measured after induction of spinal anesthesia
|
After induction of spinal anesthesia at second stage total knee arthroplasty/ an average 10 minutes
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
위 용적 1
기간: 1단계 수술, 수술 전 대기실에서 위용적 측정 중/평균 30분
|
초음파를 이용한 척추마취 유도 전 측정한 위용적
|
1단계 수술, 수술 전 대기실에서 위용적 측정 중/평균 30분
|
|
Gastric volume 2
기간: Second stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
|
Gastric volume measured before induction of spinal anesthesia using ultrasound
|
Second stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
|
|
Anxiety scale 1
기간: First stage operation, one day before surgery/ an average of 30 minutes
|
Anxiety scale measured before surgery
|
First stage operation, one day before surgery/ an average of 30 minutes
|
|
Anxiety scale 2
기간: Second stage operation, one day before surgery/ an average of 30 minutes
|
Anxiety scale measured before surgery
|
Second stage operation, one day before surgery/ an average of 30 minutes
|
공동 작업자 및 조사자
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (예상)
연구 완료 (예상)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .