The Effect of Stress on the Residual Gastric Volume
The Effect of Stress on the Residual Gastric Volume in Older Adults Undergoing Staged-bilateral Total Knee Arthroplasty After Drinking Carbohydrate-containing Fluids: A Prospective Observational Study
In our institution, many patients undergo staged bilateral total knee arthroplasty at weekly intervals, and most of the patients are older adults with degenerative arthritis. As recommended, the older adult patients who undergoing total knee arthroplasty drink carbohydrate-containing fluid (400 ml) 2 hours prior to surgery. In this type of surgery, there are additional points to consider when applying the fasting guidelines. This is because, in addition to the factor of advanced age, which can affect gastric emptying time, the patient's physical, medical, and psychological conditions at the first and the second operation may be different. For example, the effect of the acute pain that occurs after the first total knee arthroplasty and subsequent opioids administered on gastric motility cannot be ignored. However, to date, there have been no studies examining the association of stress (emotional and surgical) and residual gastric volume of older adult patients with staged bilateral total knee arthroplasty and whether there is a difference according to the stage when carbohydrate-containing fluid is ingested.
In the present study, the investigators will evaluate the effect of emotional stress, surgical stress, pain, and the use of opioids on the residual gastric volume in older adults undergoing staged-bilateral total knee arthroplasty.
研究概览
研究类型
注册 (预期的)
联系人和位置
学习联系方式
- 姓名:Hyun-Jung Shin, MD., PhD.
- 电话号码:82317877508
- 邮箱:hjshin.anesth@gmail.com
学习地点
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Gyeonggi-do
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Seongnam-si、Gyeonggi-do、大韩民国、13620
- 招聘中
- Seoul National University Bundang Hospital
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接触:
- Hyun-Jung Shin, MD., PhD.
- 邮箱:hjshin.anesth@gmail.com
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首席研究员:
- Hyo-Seok Na, MD., PhD.
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Patients scheduled for staged bilateral total knee arthroplasty aged ≥ 65
- American Society of Anesthesiologists physical status classification 1, 2, and 3
- Body mass index < 35 kg/cm2
- Patients administered carbohydrate-containing fluid 2 hours prior to surgery
Exclusion Criteria:
- Previous surgery of the upper gastrointestinal tract
- Achalasia
- Diabetes
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
干预/治疗 |
---|---|
C组
患者在手术前 2 小时饮用碳水化合物液。
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碳水化合物液体的给药
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Level of stress hormone 1
大体时间:After induction of spinal anesthesia at first stage total knee arthroplasty/ an average 10 minutes
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Stress hormone (interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α) measured after induction of spinal anesthesia
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After induction of spinal anesthesia at first stage total knee arthroplasty/ an average 10 minutes
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Level of stress hormone 2
大体时间:After induction of spinal anesthesia at second stage total knee arthroplasty/ an average 10 minutes
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Stress hormone (interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α) measured after induction of spinal anesthesia
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After induction of spinal anesthesia at second stage total knee arthroplasty/ an average 10 minutes
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
胃容积 1
大体时间:第一阶段手术,术前等候区胃容积测量期间/平均30分钟
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使用超声在脊髓麻醉诱导前测量胃容积
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第一阶段手术,术前等候区胃容积测量期间/平均30分钟
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Gastric volume 2
大体时间:Second stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
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Gastric volume measured before induction of spinal anesthesia using ultrasound
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Second stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
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Anxiety scale 1
大体时间:First stage operation, one day before surgery/ an average of 30 minutes
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Anxiety scale measured before surgery
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First stage operation, one day before surgery/ an average of 30 minutes
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Anxiety scale 2
大体时间:Second stage operation, one day before surgery/ an average of 30 minutes
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Anxiety scale measured before surgery
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Second stage operation, one day before surgery/ an average of 30 minutes
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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