The Effect of Stress on the Residual Gastric Volume
The Effect of Stress on the Residual Gastric Volume in Older Adults Undergoing Staged-bilateral Total Knee Arthroplasty After Drinking Carbohydrate-containing Fluids: A Prospective Observational Study
In our institution, many patients undergo staged bilateral total knee arthroplasty at weekly intervals, and most of the patients are older adults with degenerative arthritis. As recommended, the older adult patients who undergoing total knee arthroplasty drink carbohydrate-containing fluid (400 ml) 2 hours prior to surgery. In this type of surgery, there are additional points to consider when applying the fasting guidelines. This is because, in addition to the factor of advanced age, which can affect gastric emptying time, the patient's physical, medical, and psychological conditions at the first and the second operation may be different. For example, the effect of the acute pain that occurs after the first total knee arthroplasty and subsequent opioids administered on gastric motility cannot be ignored. However, to date, there have been no studies examining the association of stress (emotional and surgical) and residual gastric volume of older adult patients with staged bilateral total knee arthroplasty and whether there is a difference according to the stage when carbohydrate-containing fluid is ingested.
In the present study, the investigators will evaluate the effect of emotional stress, surgical stress, pain, and the use of opioids on the residual gastric volume in older adults undergoing staged-bilateral total knee arthroplasty.
調査の概要
研究の種類
入学 (予想される)
連絡先と場所
研究連絡先
- 名前:Hyun-Jung Shin, MD., PhD.
- 電話番号:82317877508
- メール:hjshin.anesth@gmail.com
研究場所
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Gyeonggi-do
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Seongnam-si、Gyeonggi-do、大韓民国、13620
- 募集
- Seoul National University Bundang Hospital
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コンタクト:
- Hyun-Jung Shin, MD., PhD.
- メール:hjshin.anesth@gmail.com
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主任研究者:
- Hyo-Seok Na, MD., PhD.
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-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Patients scheduled for staged bilateral total knee arthroplasty aged ≥ 65
- American Society of Anesthesiologists physical status classification 1, 2, and 3
- Body mass index < 35 kg/cm2
- Patients administered carbohydrate-containing fluid 2 hours prior to surgery
Exclusion Criteria:
- Previous surgery of the upper gastrointestinal tract
- Achalasia
- Diabetes
研究計画
研究はどのように設計されていますか?
デザインの詳細
コホートと介入
グループ/コホート |
介入・治療 |
---|---|
グループC
患者は手術の2時間前に炭水化物液体を摂取した。
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炭水化物液の投与
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Level of stress hormone 1
時間枠:After induction of spinal anesthesia at first stage total knee arthroplasty/ an average 10 minutes
|
Stress hormone (interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α) measured after induction of spinal anesthesia
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After induction of spinal anesthesia at first stage total knee arthroplasty/ an average 10 minutes
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Level of stress hormone 2
時間枠:After induction of spinal anesthesia at second stage total knee arthroplasty/ an average 10 minutes
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Stress hormone (interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α) measured after induction of spinal anesthesia
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After induction of spinal anesthesia at second stage total knee arthroplasty/ an average 10 minutes
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
胃容積1
時間枠:第一段階手術、術前保持エリアでの胃容積測定中/平均 30 分
|
脊椎麻酔導入前に超音波を使用して胃容積を測定
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第一段階手術、術前保持エリアでの胃容積測定中/平均 30 分
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Gastric volume 2
時間枠:Second stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
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Gastric volume measured before induction of spinal anesthesia using ultrasound
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Second stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
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Anxiety scale 1
時間枠:First stage operation, one day before surgery/ an average of 30 minutes
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Anxiety scale measured before surgery
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First stage operation, one day before surgery/ an average of 30 minutes
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Anxiety scale 2
時間枠:Second stage operation, one day before surgery/ an average of 30 minutes
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Anxiety scale measured before surgery
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Second stage operation, one day before surgery/ an average of 30 minutes
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協力者と研究者
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (予想される)
研究の完了 (予想される)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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