Cross-education of Skill and Strength in Healthy People Subjected to an Upper-limb Disuse Model (IMMO-CROSS)
2026년 5월 22일 업데이트: Iván Alejandro Cuyul Vásquez, Universidad Catolica de Temuco
Cross-education of Skill and Strength Through Contralateral Manual Dexterity Training in Healthy Young Adults Subjected to an Upper-limb Disuse Model: A Randomized Controlled Trial.
This randomized controlled trial aims to compare manual dexterity and strength between a group undergoing a contralateral manual dexterity training program and a no-intervention control group in healthy, physically inactive individuals subjected to an induced upper-limb disuse model.
연구 개요
상세 설명
Cross-education of skill offers promising opportunities for the rehabilitation of upper-limb musculoskeletal injuries.
An approach based on contralateral manual dexterity training could accelerate functional recovery, reduce motor skill loss during periods of immobilization, and optimize conventional rehabilitation protocols.
However, controlled studies are needed to analyze the efficacy of specific unilateral training protocols designed to maximize cross-education before clinical translation.
To date, no experimental studies have been published on healthy individuals subjected to upper-limb disuse models alongside contralateral skill training involving functional tasks.
This cross-education effect could potentially prevent the loss of manual dexterity and strength that occurs during immobilization.
For this research, a contralateral manual dexterity training protocol was developed based on the functional limitations commonly experienced by individuals with forearm and hand musculoskeletal injuries (e.g., distal radius fractures, wrist sprains, carpal tunnel syndrome, and tendinopathies).
Additionally, the protocol incorporates characteristics from training programs that have demonstrated the greatest cross-education effect.
연구 유형
중재적
등록 (추정된)
34
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 연락처
- 이름: Iván A. Cuyul-Vásquez, PhD(c)
- 전화번호: +56452205205
- 이메일: icuyul@uct.cl
연구 장소
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Araucania
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Temuco, Araucania, 칠레, 4813302
- UCT, Facultad de ciencias de la Salud
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연락하다:
- Iván A. Cuyul-Vásquez, PhD(c)
- 전화번호: +56452205205
- 이메일: icuyul@uct.cl
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연락하다:
- Cuyul-Vásquez Iván Cuyul-Vásquez, PhD(C)
- 전화번호: +56452205205
- 이메일: icuyul@uct.cl
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
예
설명
Inclusion Criteria:
- Individuals will be eligible for inclusion if they are right-handed adults aged 18 to 35 years with a body mass index (BMI) between 18.5 and 30 kg/m².
- Individuals must be classified as physically inactive, defined as not meeting the World Health Organization criteria of at least 150 minutes of moderate-intensity physical activity or 75 minutes of vigorous-intensity physical activity per week.
Exclusion Criteria:
- Individuals who have engaged in physical training (e.g., any form of strength or aerobic exercise) or specific manual dexterity training within the past 6 months. - Individuals who regularly participate in artistic, occupational, or sporting activities requiring high levels of manual dexterity (e.g., musicians, gamers, craftspeople).
- Individuals with a history of orthopedic or traumatic injuries affecting either upper extremity. Individuals with pathologies or conditions that preclude safe training (e.g., uncontrolled hypertension, or visual, auditory, or cognitive impairments [for example, dyscalculia]).
- Individuals currently using nutritional supplements or medications that interfere with the regulation of skeletal muscle mass and strength (e.g., whey protein, creatine) or the central nervous system (e.g., antidepressants, anxiolytics, hypnotics).
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 더블
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: Contralateral manual dexterity training
Participants in the experimental group will perform contralateral manual dexterity training focused on moving 0.5, 1.0, or 1.5 kg cylinders using different grips and movements across various planes on a gridded board.
Participants will execute various grips to place the cylinders into the quadrants indicated on a smartphone screen.
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The subjects in the experimental group will perform contralateral manual dexterity training focused on moving cylinders of 0.5, 1 or 1.5 kilos with grips and movements in different planes on a gridded board.
Participants will have to develop different grips and place the cylinders in the quadrants indicated on a smartphone screen.
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간섭 없음: Control group without intervention
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Fine Manual Dexterity
기간: Baseline and day 7
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Fine manual dexterity will be assessed using the Functional Dexterity test (FDT).
Using a stopwatch, the evaluator records the total time in seconds that the participant takes to complete the task.
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Baseline and day 7
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Force control
기간: Baseline and day 7
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In a seated position with the elbow flexed, participants will perform isometric contractions to reach a target torque guided by real-time visual feedback.
The accuracy of maintaining these contractions in the wrist flexor and extensor muscles will be assessed using a Humac Norm isokinetic dynamometer (Computer Sports Medicine, Inc., Stoughton, MA, USA).
Participants will perform a continuous 60-second isometric contraction exercise.
During this period, participants will adjust their force level to between 10% and 30% of their maximum voluntary contraction (MVC) at 10-second intervals.
Three attempts will be performed per limb.
The Root Mean Square Error (RMSE) will be recorded.
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Baseline and day 7
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Gross Manual Dexterity
기간: Baseline and day 7
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This gross manual dexterity will be assessed using the same task performed during the experimental group's contralateral manual dexterity training.
Specifically, participants will complete 15 trials, moving cylinders of varying weights across a gridded board following a sequence displayed on a smartphone.
The time required to complete these 15 trials will be recorded.
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Baseline and day 7
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Handgrip strength
기간: Baseline and day 7
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Maximum lumbrical and cylindrical grip strength will be assessed using a Jamar Plus+ digital hand dynamometer.
The highest value from three attempts will be recorded for each assessment
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Baseline and day 7
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Joint Position Sense Test
기간: Baseline and day 7
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Proprioception: Wrist flexion-extension joint position sense will be assessed using the Joint Position Sense Test (JPST).
All measurements will be conducted with a Humac Norm isokinetic dynamometer (Computer Sports Medicine, Inc., Stoughton, MA, USA).
Three attempts will be made per limb.
The absolute error (difference in degrees between 30° and the angle achieved during the test) will be recorded.
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Baseline and day 7
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Left/right judgment
기간: Baseline and day 7
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Left/right judgment will be assessed using the Recognise™ application (Noigroup, Adelaide, Australia).
Performance on the laterality judgment task was quantified using the Inverse Efficiency Score (IES), calculated as the average reaction time of correct responses divided by the proportion of correct responses (IES = RT / PC). 3 blocks of 20 images (60 images total).
Maximum exposure time: 5 seconds per image.
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Baseline and day 7
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기타 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Physical activity level
기간: Baseline and day 7
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Weekly metabolic equivalents (MET-min/week) will be calculated using the validated Spanish version of the Global physical activity questionnaire (GPAQ).
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Baseline and day 7
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Psychological Distress
기간: Baseline
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Psychological Distress, including symptoms of depression, anxiety, and stress, will be assessed using the 21-item Depression, Anxiety and Stress Scale (DASS-21).
This self-report instrument will be used to quantify the severity of emotional distress across these three domains.
This scale has a minimum score of 0 and a maximum of 126 points (total score calculated by doubling the sum of the 21 items).
Higher scores in DASS-21 indicate greater psychological distress.
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Baseline
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Sleep Quality:
기간: Baseline
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Sleep disturbances and overall sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI).
This scale has a minimum score of 0 and a maximum of 21 points (higher scores indicate worse sleep quality)
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Baseline
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Daily steps
기간: During 7 days of immobilization
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Physical activity will be monitored using a Xiaomi Band 9 smartwatch (number of daily steps), which participants will wear throughout the seven-day mobilization period.
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During 7 days of immobilization
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Sleep time
기간: During 7 days of immobilization
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Sleep time will be measured using a Xiaomi Band 9 smartwatch (hours), which participants will wear throughout the seven-day immobilization period.
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During 7 days of immobilization
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공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (추정된)
2026년 5월 25일
기본 완료 (추정된)
2026년 10월 1일
연구 완료 (추정된)
2027년 1월 30일
연구 등록 날짜
최초 제출
2026년 5월 14일
QC 기준을 충족하는 최초 제출
2026년 5월 22일
처음 게시됨 (실제)
2026년 5월 29일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2026년 5월 29일
QC 기준을 충족하는 마지막 업데이트 제출
2026년 5월 22일
마지막으로 확인됨
2026년 5월 1일
추가 정보
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