Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability
Comparison of Ozone and Conventional Socket Disinfection in Dental Implant Placement in Terms of Primary Stability
Studie Overzicht
Toestand
Interventie / Behandeling
Gedetailleerde beschrijving
Primary implant stability is a key determinant of successful osseointegration and long-term implant survival. Various implant site disinfection methods have been proposed to reduce the microbial load before implant placement. Ozone possesses antimicrobial and biostimulatory properties and may improve the biological environment for implant healing compared with conventional implant site disinfection.
The purpose of this randomized split-mouth controlled clinical trial is to compare ozone implant site disinfection with conventional implant site disinfection in terms of primary and early secondary implant stability.
Systemically healthy adults requiring at least two dental implants in symmetrical or contralateral edentulous sites will be enrolled. According to a randomized split-mouth design, one implant site will receive ozone disinfection before implant placement, whereas the paired implant site will receive conventional disinfection. This design allows each participant to serve as their own control, thereby minimizing inter-individual variability.
Primary implant stability will be assessed immediately after implant placement using insertion torque measurements and resonance frequency analysis (Implant Stability Quotient, ISQ). Secondary implant stability will be evaluated by resonance frequency analysis at the 3-month follow-up during healing abutment placement. All clinical procedures will be standardized and performed by experienced clinicians. The study aims to determine whether ozone implant site disinfection provides superior implant stability during the early osseointegration period compared with conventional implant site disinfection.
Studietype
Inschrijving (Werkelijk)
Fase
- Niet toepasbaar
Contacten en locaties
Studie Locaties
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Merkez
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Adıyaman, Merkez, Turkije (Türkiye), 02030
- Faculty of Dentistry, Adıyaman University
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Deelname Criteria
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Volwassen
- Oudere volwassene
Accepteert gezonde vrijwilligers
Beschrijving
Inclusion Criteria:
- Adults aged 18 years or older.
- Systemically healthy individuals requiring at least two dental implants.
- Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement.
- Adequate bone volume for implant placement without the need for simultaneous bone augmentation.
- Ability and willingness to provide written informed consent and comply with the study protocol.
Exclusion Criteria:
- Adults aged 18 years or older.
- Systemically healthy individuals requiring at least two dental implants.
- Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement.
- Adequate bone volume for implant placement without the need for simultaneous bone augmentation.
- Ability and willingness to provide written informed consent and comply with the study protocol.
Studie plan
Hoe is de studie opgezet?
Ontwerpdetails
- Primair doel: Behandeling
- Toewijzing: Gerandomiseerd
- Interventioneel model: Parallelle opdracht
- Masker: Geen (open label)
Wapens en interventies
Deelnemersgroep / Arm |
Interventie / Behandeling |
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Experimenteel: Ozone Disinfection
Implant sites assigned to the experimental intervention receive ozone disinfection before dental implant placement.
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Before dental implant placement, the implant site assigned to the experimental intervention is disinfected using ozone according to the study protocol.
In this randomized split-mouth design, each participant receives ozone disinfection at one implant site, while the paired contralateral or symmetrical implant site receives conventional disinfection.
Implant stability is evaluated immediately after implant placement using insertion torque and resonance frequency analysis (ISQ), and again after 3 months using ISQ.
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Experimenteel: Conventional Disinfection
Implant sites assigned to the control intervention receive conventional implant site disinfection before dental implant placement.
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Before dental implant placement, the implant site assigned to the control intervention is disinfected using the conventional disinfection protocol.
In this randomized split-mouth design, each participant receives conventional disinfection at one implant site, while the paired contralateral or symmetrical implant site receives ozone disinfection.
Implant stability is evaluated immediately after implant placement using insertion torque and resonance frequency analysis (ISQ), and again after 3 months using ISQ.
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Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
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Primary Implant Stability (Insertion Torque)
Tijdsspanne: Immediately after implant placement
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Primary implant stability will be assessed immediately after implant placement by measuring insertion torque (Ncm).
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Immediately after implant placement
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Medewerkers en onderzoekers
Sponsor
Studie record data
Bestudeer belangrijke data
Studie start (Werkelijk)
Primaire voltooiing (Geschat)
Studie voltooiing (Geschat)
Studieregistratiedata
Eerst ingediend
Eerst ingediend dat voldeed aan de QC-criteria
Eerst geplaatst (Werkelijk)
Updates van studierecords
Laatste update geplaatst (Werkelijk)
Laatste update ingediend die voldeed aan QC-criteria
Laatst geverifieerd
Meer informatie
Termen gerelateerd aan deze studie
Trefwoorden
Andere studie-ID-nummers
- HRU-25.18.55
Plan Individuele Deelnemersgegevens (IPD)
Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?
Beschrijving IPD-plan
Informatie over medicijnen en apparaten, studiedocumenten
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