- ICH GCP
- US Clinical Trials Registry
- Klinisk utprøving NCT07760597
Effects of Exercise Frequency on Muscle Size and Strength in Healthy, Untrained Young Adults (FREQ)
11. august 2026 oppdatert av: Cameron Mitchell
Resistance training (RT) is important for building and maintaining healthy muscles.
An exercise frequency called "exercise snacks" involves short bursts of exercise throughout the day (~5-15 minutes), but no studies have examined a gym-based RT exercise snack program.
The invetigators will randomize 40 participants into one of two groups for 10 weeks: the control group will complete two full-body workouts per week (standard-frequency) and the experimental group will complete 10 mini-workouts per week (high-frequency).
Muscle hypertrophy (size) and strength will be measured before and after the exercise program to determine if the participants had the same or different results.
Studieoversikt
Status
Rekruttering
Studietype
Intervensjonell
Registrering (Antatt)
40
Fase
- Ikke aktuelt
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiekontakt
- Navn: Cameron Mitchell, PhD
- Telefonnummer: 604-827-2072
- E-post: cameron.mitchell@ubc.ca
Studiesteder
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British Columbia
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Vancouver, British Columbia, Canada, V6T 1Z1
- Rekruttering
- University of British Columbia | Gateway Health Building
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Ta kontakt med:
- Cameron Mitchell, PhD
- Telefonnummer: 604-827-2072
- E-post: cameron.mitchell@ubc.ca
-
Ta kontakt med:
- E-post: hdennis@student.ubc.ca
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Underetterforsker:
- Haley Dennis, MSc
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-
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
Tar imot friske frivillige
Ja
Beskrivelse
Inclusion Criteria:
- Can fluently read and write in English
- Lives, works, and/or studies at or near the Gateway Health Building (where all study visits will occur)
- Willing and able to commit to 2 or 10 in-person training sessions per week for 10 continuous weeks, as well as one week of testing before the training period and one week of testing after the training period
- Has continuous access to smartphone or other device that they can use to access the Technogym app
- Answers "No" to all questions on the Canadian Society for Exercise Physiology - Get Active Questonnaire (CSEP-GAQ) or has their doctor's approval to participate
Exclusion Criteria:
- Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
- Lung disease, kidney disease, or liver disease
- Current diagnosis of type 1 diabetes, type 2 diabetes, or cancer
- Medical conditions that limit their ability to undertake strenuous physical activity
- Regular use of any medications that may affect muscle physiology or body composition (i.e. benzodiazepines, hormone replacement therapy, ADHD medication, Metformin, Ozempic)
- Participated in consistent resistance exercise training more than twice per month in the previous 12 months
- Participated in consistent moderate or vigorous aerobic training more than twice per week in the previous 12 months, or planning to start consistent training in the next few months
- Significant gain or loss of body mass in the past 6 months (greater than 2 kg)
- Current smoker (including but not limited to cigarettes, e-cigarettes, or vaping)
- Body Mass Index of less than 18 kg/m2 or over 30 kg/m2
- Pregnancy or breastfeeding
- Currently taking blood thinners
- Allergic to Tegaderm medical tape (used with the activity trackers)
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Grunnvitenskap
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Ingen (Open Label)
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
|
Aktiv komparator: Standard-frequency resistance training
|
Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting.
Training at an exercise frequency of two sessions per week (around 45-60 minutes per session).
|
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Eksperimentell: High-frequency resistance training
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Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting.
Training at an exercise frequency of 10 brief sessions per week (around 8-12 minutes per session).
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tidsramme |
|---|---|
|
Change in Total Body Skeletal Muscle Mass Measured using the D3-Creatine Dilution Method
Tidsramme: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Change in Total Body Muscle Size Measured as Cross-sectional Area using Muscle Ultrasound Imaging
Tidsramme: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
Muscle ultrasound imaging will be conducted on one randomly selected side of the body (left or right) for each participant.
Scans will be analyzed to determine the cross-sectional area of the following seven muscles: rectus femoris, vastus lateralis, biceps brachii, pectoralis major, latissimus dorsi, triceps brachii, and hamstring group (semitendinosus, semimembranosus, and long head of biceps femoris).
|
From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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Change in Muscle Strength Measured as the One-Repetition Maximum of Back Squat and Bench Press
Tidsramme: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
One-repetition maximums will be measured using a Quantum Synchro Smith Machine.
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
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Change in Skeletal Muscle Power Measured at Various Relative Loads for Back Squat and Bench Press
Tidsramme: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
At enrolment (Week 1), power will be measured using a Quantum Synchro Smith Machine at 40%, 50%, 60%, 70%, and 80% of the participant's initial one-repetition maximum (1RM) for back squat and bench press.
At the end of the exercise training phase (Week 12), if a participant's 1RM has increased by less than 25%, power will be measured at the same relative loads.
If a participant's 1RM has increased by 25-49%, power will be measured at 50%, 60%, 70%, 80%, and 90% of the participant's initial 1RM (in this case, 90% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).
If a participant's 1RM has increased by 50% or greater, power will be measured at 60%, 70%, 80%, 90%, and 100% of the participant's initial 1RM (in this case, 100% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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Participant Satisfaction with the Exercise Program
Tidsramme: At the end of the exercise training phase (Week 12)
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Participant satisfaction with the exercise program will be measured using a modified Intrinsic Motivation Inventory (subscales of "Interest/Enjoyment", "Percieved Competence", "Effort/Importance", and "Value/Usefullness").
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At the end of the exercise training phase (Week 12)
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Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart (Faktiske)
12. august 2026
Primær fullføring (Antatt)
1. juni 2027
Studiet fullført (Antatt)
1. juni 2027
Datoer for studieregistrering
Først innsendt
7. august 2026
Først innsendt som oppfylte QC-kriteriene
7. august 2026
Først lagt ut (Faktiske)
12. august 2026
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
13. august 2026
Siste oppdatering sendt inn som oppfylte QC-kriteriene
11. august 2026
Sist bekreftet
1. august 2026
Mer informasjon
Begreper knyttet til denne studien
Nøkkelord
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- H26-01331
Plan for individuelle deltakerdata (IPD)
Planlegger du å dele individuelle deltakerdata (IPD)?
NEI
IPD-planbeskrivelse
The dataset will contain potentially identifying information (age, height, and weight) of people in a relatively small geographic area, so individual participant data will not be shared with other researchers.
Legemiddel- og utstyrsinformasjon, studiedokumenter
Studerer et amerikansk FDA-regulert medikamentprodukt
Nei
Studerer et amerikansk FDA-regulert enhetsprodukt
Nei
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