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- Klinische proef NCT07760597
Effects of Exercise Frequency on Muscle Size and Strength in Healthy, Untrained Young Adults (FREQ)
11 augustus 2026 bijgewerkt door: Cameron Mitchell
Resistance training (RT) is important for building and maintaining healthy muscles.
An exercise frequency called "exercise snacks" involves short bursts of exercise throughout the day (~5-15 minutes), but no studies have examined a gym-based RT exercise snack program.
The invetigators will randomize 40 participants into one of two groups for 10 weeks: the control group will complete two full-body workouts per week (standard-frequency) and the experimental group will complete 10 mini-workouts per week (high-frequency).
Muscle hypertrophy (size) and strength will be measured before and after the exercise program to determine if the participants had the same or different results.
Studie Overzicht
Toestand
Werving
Studietype
Ingrijpend
Inschrijving (Geschat)
40
Fase
- Niet toepasbaar
Contacten en locaties
In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.
Studiecontact
- Naam: Cameron Mitchell, PhD
- Telefoonnummer: 604-827-2072
- E-mail: cameron.mitchell@ubc.ca
Studie Locaties
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British Columbia
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Vancouver, British Columbia, Canada, V6T 1Z1
- Werving
- University of British Columbia | Gateway Health Building
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Contact:
- Cameron Mitchell, PhD
- Telefoonnummer: 604-827-2072
- E-mail: cameron.mitchell@ubc.ca
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Contact:
- E-mail: hdennis@student.ubc.ca
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Onderonderzoeker:
- Haley Dennis, MSc
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Deelname Criteria
Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Volwassen
Accepteert gezonde vrijwilligers
Ja
Beschrijving
Inclusion Criteria:
- Can fluently read and write in English
- Lives, works, and/or studies at or near the Gateway Health Building (where all study visits will occur)
- Willing and able to commit to 2 or 10 in-person training sessions per week for 10 continuous weeks, as well as one week of testing before the training period and one week of testing after the training period
- Has continuous access to smartphone or other device that they can use to access the Technogym app
- Answers "No" to all questions on the Canadian Society for Exercise Physiology - Get Active Questonnaire (CSEP-GAQ) or has their doctor's approval to participate
Exclusion Criteria:
- Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
- Lung disease, kidney disease, or liver disease
- Current diagnosis of type 1 diabetes, type 2 diabetes, or cancer
- Medical conditions that limit their ability to undertake strenuous physical activity
- Regular use of any medications that may affect muscle physiology or body composition (i.e. benzodiazepines, hormone replacement therapy, ADHD medication, Metformin, Ozempic)
- Participated in consistent resistance exercise training more than twice per month in the previous 12 months
- Participated in consistent moderate or vigorous aerobic training more than twice per week in the previous 12 months, or planning to start consistent training in the next few months
- Significant gain or loss of body mass in the past 6 months (greater than 2 kg)
- Current smoker (including but not limited to cigarettes, e-cigarettes, or vaping)
- Body Mass Index of less than 18 kg/m2 or over 30 kg/m2
- Pregnancy or breastfeeding
- Currently taking blood thinners
- Allergic to Tegaderm medical tape (used with the activity trackers)
Studie plan
Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.
Hoe is de studie opgezet?
Ontwerpdetails
- Primair doel: Fundamentele wetenschap
- Toewijzing: Gerandomiseerd
- Interventioneel model: Parallelle opdracht
- Masker: Geen (open label)
Wapens en interventies
Deelnemersgroep / Arm |
Interventie / Behandeling |
|---|---|
|
Actieve vergelijker: Standard-frequency resistance training
|
Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting.
Training at an exercise frequency of two sessions per week (around 45-60 minutes per session).
|
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Experimenteel: High-frequency resistance training
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Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting.
Training at an exercise frequency of 10 brief sessions per week (around 8-12 minutes per session).
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Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Tijdsspanne |
|---|---|
|
Change in Total Body Skeletal Muscle Mass Measured using the D3-Creatine Dilution Method
Tijdsspanne: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
Secundaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
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Change in Total Body Muscle Size Measured as Cross-sectional Area using Muscle Ultrasound Imaging
Tijdsspanne: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
Muscle ultrasound imaging will be conducted on one randomly selected side of the body (left or right) for each participant.
Scans will be analyzed to determine the cross-sectional area of the following seven muscles: rectus femoris, vastus lateralis, biceps brachii, pectoralis major, latissimus dorsi, triceps brachii, and hamstring group (semitendinosus, semimembranosus, and long head of biceps femoris).
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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Change in Muscle Strength Measured as the One-Repetition Maximum of Back Squat and Bench Press
Tijdsspanne: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
One-repetition maximums will be measured using a Quantum Synchro Smith Machine.
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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Change in Skeletal Muscle Power Measured at Various Relative Loads for Back Squat and Bench Press
Tijdsspanne: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
At enrolment (Week 1), power will be measured using a Quantum Synchro Smith Machine at 40%, 50%, 60%, 70%, and 80% of the participant's initial one-repetition maximum (1RM) for back squat and bench press.
At the end of the exercise training phase (Week 12), if a participant's 1RM has increased by less than 25%, power will be measured at the same relative loads.
If a participant's 1RM has increased by 25-49%, power will be measured at 50%, 60%, 70%, 80%, and 90% of the participant's initial 1RM (in this case, 90% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).
If a participant's 1RM has increased by 50% or greater, power will be measured at 60%, 70%, 80%, 90%, and 100% of the participant's initial 1RM (in this case, 100% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
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Participant Satisfaction with the Exercise Program
Tijdsspanne: At the end of the exercise training phase (Week 12)
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Participant satisfaction with the exercise program will be measured using a modified Intrinsic Motivation Inventory (subscales of "Interest/Enjoyment", "Percieved Competence", "Effort/Importance", and "Value/Usefullness").
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At the end of the exercise training phase (Week 12)
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Medewerkers en onderzoekers
Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.
Sponsor
Studie record data
Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.
Bestudeer belangrijke data
Studie start (Werkelijk)
12 augustus 2026
Primaire voltooiing (Geschat)
1 juni 2027
Studie voltooiing (Geschat)
1 juni 2027
Studieregistratiedata
Eerst ingediend
7 augustus 2026
Eerst ingediend dat voldeed aan de QC-criteria
7 augustus 2026
Eerst geplaatst (Werkelijk)
12 augustus 2026
Updates van studierecords
Laatste update geplaatst (Werkelijk)
13 augustus 2026
Laatste update ingediend die voldeed aan QC-criteria
11 augustus 2026
Laatst geverifieerd
1 augustus 2026
Meer informatie
Termen gerelateerd aan deze studie
Trefwoorden
Aanvullende relevante MeSH-voorwaarden
Andere studie-ID-nummers
- H26-01331
Plan Individuele Deelnemersgegevens (IPD)
Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?
NEE
Beschrijving IPD-plan
The dataset will contain potentially identifying information (age, height, and weight) of people in a relatively small geographic area, so individual participant data will not be shared with other researchers.
Informatie over medicijnen en apparaten, studiedocumenten
Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel
Nee
Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct
Nee
Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .