- ICH GCP
- Amerikanska kliniska prövningsregistret
- Klinisk prövning NCT07760597
Effects of Exercise Frequency on Muscle Size and Strength in Healthy, Untrained Young Adults (FREQ)
11 augusti 2026 uppdaterad av: Cameron Mitchell
Resistance training (RT) is important for building and maintaining healthy muscles.
An exercise frequency called "exercise snacks" involves short bursts of exercise throughout the day (~5-15 minutes), but no studies have examined a gym-based RT exercise snack program.
The invetigators will randomize 40 participants into one of two groups for 10 weeks: the control group will complete two full-body workouts per week (standard-frequency) and the experimental group will complete 10 mini-workouts per week (high-frequency).
Muscle hypertrophy (size) and strength will be measured before and after the exercise program to determine if the participants had the same or different results.
Studieöversikt
Status
Rekrytering
Betingelser
Intervention / Behandling
Studietyp
Interventionell
Inskrivning (Beräknad)
40
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studiekontakt
- Namn: Cameron Mitchell, PhD
- Telefonnummer: 604-827-2072
- E-post: cameron.mitchell@ubc.ca
Studieorter
-
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British Columbia
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Vancouver, British Columbia, Kanada, V6T 1Z1
- Rekrytering
- University of British Columbia | Gateway Health Building
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Kontakt:
- Cameron Mitchell, PhD
- Telefonnummer: 604-827-2072
- E-post: cameron.mitchell@ubc.ca
-
Kontakt:
- E-post: hdennis@student.ubc.ca
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Underutredare:
- Haley Dennis, MSc
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-
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
Tar emot friska volontärer
Ja
Beskrivning
Inclusion Criteria:
- Can fluently read and write in English
- Lives, works, and/or studies at or near the Gateway Health Building (where all study visits will occur)
- Willing and able to commit to 2 or 10 in-person training sessions per week for 10 continuous weeks, as well as one week of testing before the training period and one week of testing after the training period
- Has continuous access to smartphone or other device that they can use to access the Technogym app
- Answers "No" to all questions on the Canadian Society for Exercise Physiology - Get Active Questonnaire (CSEP-GAQ) or has their doctor's approval to participate
Exclusion Criteria:
- Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
- Lung disease, kidney disease, or liver disease
- Current diagnosis of type 1 diabetes, type 2 diabetes, or cancer
- Medical conditions that limit their ability to undertake strenuous physical activity
- Regular use of any medications that may affect muscle physiology or body composition (i.e. benzodiazepines, hormone replacement therapy, ADHD medication, Metformin, Ozempic)
- Participated in consistent resistance exercise training more than twice per month in the previous 12 months
- Participated in consistent moderate or vigorous aerobic training more than twice per week in the previous 12 months, or planning to start consistent training in the next few months
- Significant gain or loss of body mass in the past 6 months (greater than 2 kg)
- Current smoker (including but not limited to cigarettes, e-cigarettes, or vaping)
- Body Mass Index of less than 18 kg/m2 or over 30 kg/m2
- Pregnancy or breastfeeding
- Currently taking blood thinners
- Allergic to Tegaderm medical tape (used with the activity trackers)
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Grundläggande vetenskap
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
|
Aktiv komparator: Standard-frequency resistance training
|
Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting.
Training at an exercise frequency of two sessions per week (around 45-60 minutes per session).
|
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Experimentell: High-frequency resistance training
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Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting.
Training at an exercise frequency of 10 brief sessions per week (around 8-12 minutes per session).
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Tidsram |
|---|---|
|
Change in Total Body Skeletal Muscle Mass Measured using the D3-Creatine Dilution Method
Tidsram: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Change in Total Body Muscle Size Measured as Cross-sectional Area using Muscle Ultrasound Imaging
Tidsram: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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Muscle ultrasound imaging will be conducted on one randomly selected side of the body (left or right) for each participant.
Scans will be analyzed to determine the cross-sectional area of the following seven muscles: rectus femoris, vastus lateralis, biceps brachii, pectoralis major, latissimus dorsi, triceps brachii, and hamstring group (semitendinosus, semimembranosus, and long head of biceps femoris).
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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Change in Muscle Strength Measured as the One-Repetition Maximum of Back Squat and Bench Press
Tidsram: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
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One-repetition maximums will be measured using a Quantum Synchro Smith Machine.
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
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Change in Skeletal Muscle Power Measured at Various Relative Loads for Back Squat and Bench Press
Tidsram: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
At enrolment (Week 1), power will be measured using a Quantum Synchro Smith Machine at 40%, 50%, 60%, 70%, and 80% of the participant's initial one-repetition maximum (1RM) for back squat and bench press.
At the end of the exercise training phase (Week 12), if a participant's 1RM has increased by less than 25%, power will be measured at the same relative loads.
If a participant's 1RM has increased by 25-49%, power will be measured at 50%, 60%, 70%, 80%, and 90% of the participant's initial 1RM (in this case, 90% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).
If a participant's 1RM has increased by 50% or greater, power will be measured at 60%, 70%, 80%, 90%, and 100% of the participant's initial 1RM (in this case, 100% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).
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From enrolment (Week 1) to the end of the exercise training phase (Week 12)
|
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Participant Satisfaction with the Exercise Program
Tidsram: At the end of the exercise training phase (Week 12)
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Participant satisfaction with the exercise program will be measured using a modified Intrinsic Motivation Inventory (subscales of "Interest/Enjoyment", "Percieved Competence", "Effort/Importance", and "Value/Usefullness").
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At the end of the exercise training phase (Week 12)
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Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Faktisk)
12 augusti 2026
Primärt slutförande (Beräknad)
1 juni 2027
Avslutad studie (Beräknad)
1 juni 2027
Studieregistreringsdatum
Först inskickad
7 augusti 2026
Först inskickad som uppfyllde QC-kriterierna
7 augusti 2026
Första postat (Faktisk)
12 augusti 2026
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
13 augusti 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
11 augusti 2026
Senast verifierad
1 augusti 2026
Mer information
Termer relaterade till denna studie
Nyckelord
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- H26-01331
Plan för individuella deltagardata (IPD)
Planerar du att dela individuella deltagardata (IPD)?
NEJ
IPD-planbeskrivning
The dataset will contain potentially identifying information (age, height, and weight) of people in a relatively small geographic area, so individual participant data will not be shared with other researchers.
Läkemedels- och apparatinformation, studiedokument
Studerar en amerikansk FDA-reglerad läkemedelsprodukt
Nej
Studerar en amerikansk FDA-reglerad produktprodukt
Nej
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