Study of Blood Samples From Patients With Malignant Melanoma, Metastatic Breast Cancer, Advanced Lung Cancer, Pancreatic Cancer, or Colorectal Cancer.
Collaborative Project on Potential Serum Markers for Malignant Melanoma, Metastatic Breast, Advanced Lung Pancreatic Carcinoma and Colorectal Cancer
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in peptides and proteins and identify biomarkers related to cancer.
PURPOSE: This research study is looking at blood samples from patients with malignant melanoma, metastatic breast cancer, advanced lung cancer, pancreatic cancer, or colorectal cancer.
研究概览
详细说明
OBJECTIVES:
Primary
- To assess which potential peptide and protein markers produced by human melanoma, lung, breast, pancreatic, and colorectal cell lines may be detectable in serum of patients from these five disease groups.
Secondary
- To conduct further extensive investigation with respect to identification of the protein/peptide involved, determination of specificity for each cancer, and development of more sensitive assays to look for such markers in a wider population of patients, including those undergoing therapy.
OUTLINE: This is a multicenter study.
Blood samples are collected before surgical intervention or treatment to assess peptide and protein markers.
研究类型
注册 (实际的)
联系人和位置
学习地点
-
-
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Cork、爱尔兰
- Cork University Hospital
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Cork、爱尔兰
- Mercy University Hospital
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Dublin、爱尔兰、9
- Beaumont Hospital
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Dublin、爱尔兰
- St Luke's Hospital
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Dublin、爱尔兰、7
- Mater Misericordiae University Hospital
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Dublin、爱尔兰、4
- St. Vincent's University Hospital
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Dublin、爱尔兰、24
- Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital
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Dublin、爱尔兰、8
- St. James's Hospital
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Dublin、爱尔兰
- Mater Private Hospital
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Galway、爱尔兰
- University College Hospital
-
Letterkenny、爱尔兰
- Letterkenny General Hospital
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Limerick、爱尔兰、0009
- Mid-Western Cancer Centre at Mid-Western Regional Hospital
-
Waterford、爱尔兰
- Waterford Regional Hospital
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-
参与标准
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
DISEASE CHARACTERISTICS:
Diagnosis of 1 of the following advanced metastatic malignancies:
- Malignant melanoma
- Lung cancer
- Breast cancer
- Pancreatic carcinoma
- Colorectal cancer
- Advanced and/or metastatic disease
- Hormone receptor status not specified
PATIENT CHARACTERISTICS:
- Menopausal status not specified
PRIOR CONCURRENT THERAPY:
- Not specified
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
|
黑色素瘤
|
|
Breast
|
|
Lung
|
|
Pancreatic
|
|
Colorectal
|
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
Detection of peptide and protein markers in serum
大体时间：Ongoing
|
Ongoing
|
次要结果测量
结果测量 |
大体时间 |
|---|---|
|
Identification of the protein/peptide involved
大体时间：Ongoing
|
Ongoing
|
合作者和调查者
调查人员
- 首席研究员：Martin Clynes、National Institute for Cellular Biotechnology at Dublin City University
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
其他相关的 MeSH 术语
其他研究编号
- CTRIAL-IE (ICORG) 07-12
- EU-20949
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