Persistent Pulmonary Artery Hypertension After Valve Replacement (SALT)
Persistence of Severe Pulmonary Artery Hypertension in Patients After vaLve replacemenT
Background: Persistent severe pulmonary hypertension (PH) after mechanical valve replacement is a frequent finding in patients with severe valve-diseases. The reasons to develop PH are multifactorial and the prevalence of severe PH significantly worsens the patients´ outcome.
Aims: (i) To define the prevalence of PH in patients after valve replacement and (ii) to identify factors predicting persistent PH.
Methods: All patients which underwent valve replacement at our institution between the years 2008 -2010 will be screened retrospectively. Those patients with pre- procedural proven PH by means of right-heart catheterization will receive prospective follow-up with echocardiography. Diagnosis of persistent PH will be confirmed with right heart catheterization.
研究概览
研究类型
注册 (预期的)
联系人和位置
学习地点
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Bonn、德国、53125
- Medizinische Klinik II, University of Bonn
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Proven pulmonary hypertension before valve replacement and informed consent for data acquisition
Exclusion Criteria:
- patients do not meet inclusion criteria
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
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Valve replacement
Patients undergoing valve replacement for severe valve disease will be screened for study entry
|
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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Persistence of pulmonary hypertension after valve replacement for treatment of severe valve disease
大体时间：> 6 months after valve therapy
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> 6 months after valve therapy
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次要结果测量
结果测量 |
大体时间 |
|---|---|
|
MACCE, all cause mortality during FU
大体时间：Within 24 months after valve therapy
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Within 24 months after valve therapy
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合作者和调查者
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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