Implementing Physical Activity Guidelines for Adults With MS
A Community-based Randomized Controlled Trial Testing Implementation of the New Canadian Physical Activity Guidelines for Adults With Multiple Sclerosis.
The proposed project will evaluate two methods of implementation of the new Physical Activity Guidelines (PAGs) for Adults with Multiple Sclerosis (MS) living in two Ontario communities. The investigators will also determine if following the PAGs will improve aspects of fitness, function, quality of life and risk for cardiometabolic disease in this population. The investigators hypothesize that adherence to the PAGs will be higher in people who have been referred directly to a community-based exercise program, and that this greater adherence to physical activity will be associated with greater improvements in fitness, function and quality of life.
This randomized controlled trial will provide important information on how best to implement physical activity recommendations within the community setting; this information will be translated to key stakeholders during the final stages of the project.
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Ontario
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Hamilton、Ontario、加拿大、L8S 4K1
- McMaster University, Physical Activity Centre for Excellence
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Kingston、Ontario、加拿大、K7L 3N6
- Queens University
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Diagnosis of MS with mild-moderate disability (EDSS 1-7)
- Aged 18-60
- Medical clearance to participate in physical activity
Exclusion Criteria:
- current participation in regular physical activity (at least twice-weekly)
- other serious medical condition that might impair ability to participate in strength or aerobic exercise
学习计划
研究是如何设计的？
设计细节
- 主要用途：其他
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Direct Referral to Physical Activity
The REF group will be referred to a centre-based community exercise program in their respective community (either the MacWheelers or Revved Up) by a clinical neurologist where they will be prescribed exercise based on the PAGs for adults with MS, and according to their individual capabilities.
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Participants randomized to the Direct Referral to Physical Activity Arm will be provided with a referral to a physical activity program in their community and will be closely monitored in this program for 16 wks.
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无干预：Control
The CON group will be provided with a print copy of the PAGs and a link to an online resource for physical activity information.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Adherence to the Physical Activity Guidelines
大体时间：3 years
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Adherence to the physical activity guidelines will be analyzed by having participants fill in a weekly physical activity log that will be sent to them by email.
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3 years
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Physical Fitness
大体时间：At baseline and after the 16 week intervention
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Peak oxygen uptake, maximum muscle strength, bodyweight
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At baseline and after the 16 week intervention
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Perceived Quality of Life
大体时间：At baseline and after the 16 week intervention
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Multiple Sclerosis Quality of Life (MSQoL) scale
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At baseline and after the 16 week intervention
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Fatigue
大体时间：At baseline and after the 16 week intervention
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Multiple Sclerosis Fatigue Impact Scale (MSFIS)
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At baseline and after the 16 week intervention
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Mobility
大体时间：At baseline and after the 16 week intervention
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25ft walk test
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At baseline and after the 16 week intervention
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Blood markers of cardiovascular disease risk
大体时间：At baseline and after the 16 week intervention
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blood lipid panel, HbA1c, fasting glucose
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At baseline and after the 16 week intervention
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合作者和调查者
调查人员
- 首席研究员：Audrey L Hicks, Ph.D.、McMaster University
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- MSProject2001
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